Characteristics and Clinical Outcomes of Children With Wilms’ Tumour: A 15-year Experience in a Single Centre in Nigeria

jpedsurg.org

Wilms' tumor (WT) is the most common paediatric renal tumor and is one of the most treatment-responsive solid tumours. Survival from Wilms tumour (WT) in sub-Saharan Africa remains dismal as a result of late presentation, treatment abandonment and infrastructure deficit. The purpose of this study was to analyze the clinical outcome of children with Wilms tumour managed in a Nigerian referral centre over a 15-year period.

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Article · Dec 2023 · 1 min read

In brief

This 15-year retrospective study from Nigeria examines clinical outcomes in pediatric Wilms tumor patients, addressing the persistent challenges of late presentation, treatment abandonment, and infrastructure limitations that contribute to poor survival rates in sub-Saharan Africa compared to high-income countries.

Wilms' tumor is highly treatment-responsive, yet survival in sub-Saharan Africa remains poor due to late presentation and resource limitations.
Treatment abandonment is a major barrier to successful outcomes in pediatric Wilms' tumor cases in Nigeria.
Infrastructure deficits significantly impact the clinical management and prognosis of children with Wilms' tumor in resource-limited settings.
Single-center data over 15 years provides insight into region-specific challenges in pediatric oncology care delivery.

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