Long-term Effects of Pre-operative Testosterone and Dihydrotestosterone on Glans Width in Boys With Hypospadias

jpedsurg.org

Small glans width is a risk factor for urethroplasty complications. This study aimed to assess and compare short- and long-term effects of two pre-operative topical androgen treatment protocols on maximum glans width. Furthermore, to evaluate post-operative complications when surgery was delayed >3 months following hormonal treatment completion.

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Article · Jun 2024 · 1 min read

In brief

This study compares topical testosterone versus dihydrotestosterone for pre-operative glans augmentation in hypospadias repair, evaluating both immediate and sustained effects on glans width. It also examines surgical complication rates when urethroplasty is delayed beyond three months after completing hormonal treatment.

Small glans width increases risk of urethroplasty complications in hypospadias repair
Pre-operative topical androgens (testosterone/DHT) can increase glans width before surgery
Study compares short-term vs long-term effects of two different androgen protocols on glans dimensions
Surgical delay >3 months post-hormonal treatment may impact complication rates

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