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Mortality and surgery-related complications in very low and extreme low birth weight infants treated for esophageal atresia: a multi-center cohort study.
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Read the article on jpedsurg.org ↗Article · Aug 2025 · 1 min read
In brief
In brief
This multi-center cohort study examines mortality and surgical complication rates in very low and extremely low birth weight infants undergoing esophageal atresia repair. The research addresses a critical knowledge gap in managing this high-risk patient population and aims to inform treatment strategies and parental counseling.
- VLBW/ELBW infants with EA face elevated perioperative complication risk after surgical repair compared to normal birth weight infants.
- Current evidence on outcomes for VLBW/ELBW EA patients is limited, creating gaps in optimal treatment strategy identification.
- Multi-center cohort data is needed to establish mortality and complication benchmarks for this high-risk population.
- Better outcome data would improve parental counseling when EA is diagnosed in extremely premature or growth-restricted infants.
- Surgical EA repair in VLBW/ELBW infants requires specialized perioperative management due to compounded physiologic vulnerabilities.
Written by the GCMD Library team from the article.
Surgical esophageal atresia (EA) repair is a complex operation with high risk of perioperative complications. Infants born with very low or extreme low birth weight (VLBW or ELBW) might be even at higher risk for developing perioperative complications. However, studies about this specific patient group are scarce, resulting in a knowledge gap on the outcomes of these infants. This hampers identifying the optimal treatment strategy, but also good counselling of parents. The aim of this study was to evaluate the mortality and surgery-related complication rates of VLBW and ELBW infants with EA after surgical esophageal repair in a multi-center cohort.
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