Notable Clinical Differences Between Neonatal and Post-Neonatal Intestinal Malrotation: A Multicenter Review in Southern Japan

In brief

This multicenter study compares clinical presentations of intestinal malrotation in neonates versus older infants and children. Neonatal cases typically present with acute bilious vomiting from midgut volvulus, while post-neonatal presentations show more variable symptoms, creating diagnostic challenges for clinicians in daily practice.

• Neonatal malrotation typically presents with bilious vomiting from midgut volvulus, requiring urgent recognition.
• Post-neonatal malrotation has variable presentation, making diagnosis more challenging in older infants and children.
• Age at presentation significantly influences clinical features and diagnostic approach for intestinal malrotation.
• Clinicians should maintain high index of suspicion for malrotation beyond the neonatal period despite atypical symptoms.

Written by the GCMD Library team from the article.