Prevalence of Gastroesophageal Reflux Disease in Congenital Diaphragmatic Hernia Survivors From Infancy to Adulthood

jpedsurg.org

Gastroesophageal reflux disease (GERD) is a common comorbidity associated with congenital diaphragmatic hernia (CDH), with reported cases of Barrett's esophagus (BE) and esophageal adenocarcinoma before the age of 25. The prevalence and natural course of GERD in CDH survivors remain uncertain due to variations in diagnostic methods. We aimed to analyse the GERD prevalence from infancy through young adulthood.

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Article · Jun 2024 · 1 min read

In brief

This study examines the prevalence of gastroesophageal reflux disease across the lifespan of CDH survivors, from infancy to young adulthood. Given the serious complications including Barrett's esophagus and early-onset esophageal cancer, understanding GERD's natural course in this population is critical for surveillance protocols.

GERD is a common comorbidity in CDH survivors, with cases of Barrett's esophagus and esophageal adenocarcinoma reported before age 25.
The true prevalence and natural progression of GERD in CDH patients remain unclear due to inconsistent diagnostic approaches.
Long-term surveillance for GERD complications is warranted in CDH survivors from infancy through young adulthood.

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