Adolescent Bariatric Surgery: Pediatric Obesity 2017
Cardiovascular mortality begins to climb in the overweight range and increases definitively for adolescents at or above the 95th percentile BMI, leading to early cardiovascular death.
Host summaryThomas Inge summarizing a resource — not the host's own clinical position4:00
FAS-5 study achieved 81% participation (58 of 74 eligible) at 8-year follow-up, mostly with in-person research visits.
At 8-year mean follow-up, gastric bypass patients had a mean BMI decline of 29%.
Baseline BMI strongly correlates (R=0.75) with follow-up BMI: patients starting with BMI in the 60s end above 40, while those starting in the 40s reach near-normal BMI.
Remission rates at 8 years: 88% for diabetes, 64% for dyslipidemia, 75% for hypertension.
Among those without baseline comorbidities, incidence rates were 0% for diabetes, 50% for dyslipidemia (small denominator), and 3 of 29 developed hypertension.
Follow-up BMI predicts probability of hypertension, dyslipidemia, high CRP, high insulin, insulin resistance, and low HDL; higher residual BMI is metabolically harmful.
At 8 years, FAS-5 cohort showed low iron stores with anemia, elevated PTH, and low vitamin D in substantial numbers.
In AMOS study, non-surgical controls with severe obesity gained weight over 5 years (BMI 42→45).
Host summaryThomas Inge summarizing a resource — not the host's own clinical position25:00
AMOS gastric bypass patients had dramatic BMI reduction from 45 to 30, stable at 5 years, similar to adult controls and SOS cohort.
Host summaryThomas Inge summarizing a resource — not the host's own clinical position26:00
AMOS showed 83% dyslipidemia remission, 12 of 12 hypertension cases resolved, and 75% inflammation (CRP) resolved.
Host summaryThomas Inge summarizing a resource — not the host's own clinical position28:00
AMOS had high internal hernia rates due to unclosed mesenteric defects at laparoscopic gastric bypass; closing defects prevents this complication.
In AMOS, low vitamin D was found in >50% of gastric bypass patients and also in controls; low B12 and iron deficiency anemia were noted.
Host summaryThomas Inge summarizing a resource — not the host's own clinical position30:00
Teen Labs enrolled 242 adolescents (161 bypass, 67 sleeve, 14 band) at 5 centers; median age now 24, with 203 completing 5-year visits (72% in-clinic, 17% field).
Adding 33 sleeve gastrectomy patients to Teen Labs will provide 80% power to compare bypass vs. sleeve for outcomes including blood pressure, PTH, HDL, and BMI.
Severely obese patients have greater bone mineral density due to loading; rapid weight loss after bariatric surgery drops bone mass, raising the question of whether it stabilizes or continues to decline (bariatric bone disease).
Operating earlier after diagnosis of severe obesity may yield lower residual BMI and better long-term metabolic outcomes.
Expert opinionThomas Inge32:47
FAS-5 study had a residual mean BMI of 38 at 8 years, with many patients remaining severely obese; this residual obesity is metabolically harmful.
The 33 new sleeve patients can be enrolled within a year from consortium sites with ongoing clinical follow-up, enabling long-term comparisons.
Kanika Bowen-Jallow, MD and Faisal Qureshi, MD - 2024 Pediatric Bariatric Surgery Update Course
ERAS recommendations for bariatric surgery include carbohydrate drink the night before surgery and clear liquids up to 2 hours prior to surgery
Host summaryKanika Bowen-Jallow summarizing the discussion — not the host's own clinical position0:34
Sugar-free carbohydrate drinks should be used for diabetic patients
Host summaryKanika Bowen-Jallow summarizing the discussion — not the host's own clinical position1:30
Aprepitant is given 1-2 hours prior to surgery in pre-op and has become standard in patients with high risk for post-operative nausea
Pills given in pre-op area have never been observed in the stomach during intraoperative scoping in sleeve gastrectomy cases
DVT prophylaxis with Lovenox or subcutaneous heparin is administered at the start of the case, but there is no standard recommendation and practices vary greatly among surgeons
Host summaryKanika Bowen-Jallow summarizing the discussion — not the host's own clinical position3:00
ASMBS recommends using DVT prophylaxis intraoperatively and postoperatively before discharge, but most patients do not go home on DVT prophylaxis unless there is a specific indication such as family history
Host summaryKanika Bowen-Jallow summarizing the discussion — not the host's own clinical position3:30
Minimizing narcotics helps prevent postoperative nausea, achieved by running medications like propofol at low baseline during anesthesia
New literature demonstrates laparoscopic TAP block is not superior to local infiltration of incisions for pain control
Host summaryKanika Bowen-Jallow summarizing the discussion — not the host's own clinical position4:20
Aprepitant is given in preoperative holding before surgery, while Zofran is used in the OR prior to extubation, to achieve synergistic anti-emetic effect
The number one concern after sleeve gastrectomy is nausea, retching, and vomiting
Haldol is not used for anti-emetic purposes due to sedative effects that interfere with waking patients in the PACU