Andrew Trout

237 timestamped statements across 5 collections — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Pancreatitis · guest expert

Featured diaries

Ep 5 · 27:42
I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 27:42
I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 27:42
I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 27:42
I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 6 · 27:42
I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
quote · Pancreatitis
Ep 6 · 27:42
I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
quote · Pancreatitis

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Acute Pancreatitis 27 entries

Acute Pancreatitis

Ep 1 · 2:09
clinical Ultrasound is the initial imaging modality for suspected uncomplicated acute pancreatitis in children because it is radiation-free and gives a reasonably good look at the pancreas.
Ep 1 · 25:33
clinical The pancreas can be difficult to visualize on ultrasound in larger patients, in patients who are not NPO (stomach full of gas), or when there is ileus from inflammation; bowel gas affects ultrasound wave penetration.
Ep 1 · 25:35
quote the pancreas can be a little bit difficult to see sometimes. Especially in larger patients
Ep 1 · 28:19
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients as the goal is to identify complications (venous thrombosis, necrosis, fluid collections), not masses.
Ep 1 · 28:41
clinical Oral contrast is helpful in CT of pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but a sick patient who cannot tolerate oral contrast can still have an informative CT without it.
Ep 1 · 29:51
clinical On contrast-enhanced CT, absent enhancement in pancreatic tissue is highly concerning for necrosis.
Ep 1 · 34:03
clinical In MRI of the pancreas after acute attacks have resolved, a prominent pancreatic duct (visible as a white stripe) and some atrophy/irregularity of contour may be seen, but these findings alone are not diagnostic of chronic pancreatitis.
Ep 1 · 42:34
clinical Evidence for secretin-enhanced MRCP in pediatric pancreatitis is limited; even adult literature shows iffy data on added value, though it may improve visualization of ductal anomalies in some cases.
Ep 1 · 42:49
quote when you have it's. Often in the chronic pancreatitic patients or the acute recurrence that we're doing these MR exams and they've had enough attacks that generally the ducts dilated and you can see it without secretin

Acute and Acute Recurrent Pancreatitis: Pancreatic Disease

Ep 5 · 3:43
clinical Ultrasound should be the initial imaging modality for suspected uncomplicated acute pancreatitis because it is radiation-free and provides a reasonably good look at the pancreas.
Ep 5 · 3:43
clinical Ultrasound should be the initial imaging modality for suspected uncomplicated acute pancreatitis because it is radiation-free and provides a reasonably good look at the pancreas.
Ep 5 · 27:42
quote I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 27:42
quote I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 33:31
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients unless evaluating for masses.
Ep 5 · 33:31
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients unless evaluating for masses.
Ep 5 · 33:50
clinical Oral contrast is helpful in CT for pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but the exam can provide substantial information without it if the patient cannot tolerate oral contrast.
Ep 5 · 33:50
clinical Oral contrast is helpful in CT for pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but the exam can provide substantial information without it if the patient cannot tolerate oral contrast.
Ep 5 · 45:01
opinion The added value of secretin-enhanced MRCP in pediatric pancreatitis is not well established; even adult literature shows limited evidence, though it may improve visualization of ductal anomalies in select cases.
Ep 5 · 45:01
opinion The added value of secretin-enhanced MRCP in pediatric pancreatitis is not well established; even adult literature shows limited evidence, though it may improve visualization of ductal anomalies in select cases.

Chronic Pancreatitis, Function Tests, & Pain Management: Pancreatic Disease

Ep 3 · 29:53
guideline MR pancreatic function testing acquires identical imaging both prior to and following secretin administration, with about 15 minutes between pre and post imaging
Ep 3 · 32:00
clinical MR sequences can be thresholded to quantify the volume of fluid secreted in response to secretin by subtracting pre from post measurements
Ep 3 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, it is unclear whether secretin is needed to increase conspicuity of the duct

Acute Pancreatitis

Ep 6 · 2:09
clinical Ultrasound is the initial imaging modality for suspected uncomplicated acute pancreatitis; it is radiation-free and gives a reasonably good look at the pancreas, but is limited for evaluating complications.
Ep 6 · 28:19
clinical For pediatric pancreatitis CT, a portal venous phase is sufficient (no multi-phase needed); oral contrast helps separate fluid-filled bowel from pancreatic fluid collections but is not a deal-breaker if patient cannot tolerate it.
Ep 6 · 29:51
quote when we see absent enhancement like that, that's highly concerning for necrosis within the. Pancreas.
Ep 6 · 29:51
clinical Absent enhancement on contrast-enhanced CT is highly concerning for pancreatic necrosis.
Ep 6 · 42:34
opinion Secretin-enhanced MRCP has unclear added value in pediatric pancreatitis; adult literature data is 'iffy.' In acute recurrent or chronic pancreatitis patients, ducts are often dilated enough to visualize without secretin.

Acute and Acute Recurrent Pancreatitis: Pancreatic Disease

Ep 5 · 3:43
clinical Ultrasound should be the initial imaging modality for suspected uncomplicated acute pancreatitis because it is radiation-free and provides a reasonably good look at the pancreas.
Ep 5 · 3:43
clinical Ultrasound should be the initial imaging modality for suspected uncomplicated acute pancreatitis because it is radiation-free and provides a reasonably good look at the pancreas.
Ep 5 · 27:42
quote I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 27:42
quote I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 5 · 33:31
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients unless evaluating for masses.
Ep 5 · 33:31
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients unless evaluating for masses.
Ep 5 · 33:50
clinical Oral contrast is helpful in CT for pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but the exam can provide substantial information without it if the patient cannot tolerate oral contrast.
Ep 5 · 33:50
clinical Oral contrast is helpful in CT for pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but the exam can provide substantial information without it if the patient cannot tolerate oral contrast.
Ep 5 · 45:01
opinion The added value of secretin-enhanced MRCP in pediatric pancreatitis is not well established; even adult literature shows limited evidence, though it may improve visualization of ductal anomalies in select cases.
Ep 5 · 45:01
opinion The added value of secretin-enhanced MRCP in pediatric pancreatitis is not well established; even adult literature shows limited evidence, though it may improve visualization of ductal anomalies in select cases.

Function Tests & Pain Management: Pancreatic Disease

Ep 3 · 5:07
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing is to non-invasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 3 · 5:18
clinical MR pancreatic function testing acquires identical imaging pre- and post-secretin to quantify the volume of fluid secreted into the gastrointestinal tract.
Ep 3 · 6:27
clinical The delay between pre- and post-secretin MR imaging is about 15 minutes to allow fluid accumulation.
Ep 3 · 7:38
clinical MR-PFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin from post-secretin fluid volume.
Ep 3 · 8:13
clinical Phantom studies have proven that MR can accurately quantitate fluid volume.
Ep 3 · 8:13
quote We've proven that we can accurately quantitate fluid by measuring phantoms, so you can put phantoms in the MR scanner and you can prove that you can actually quantitate the fluid.
Ep 3 · 8:28
clinical Preliminary data in about 35 patients are examining correlation between MR-PFT and endoscopic pancreatic function testing.
Ep 3 · 8:49
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt, and so it may be that there's a size dependency, a weight dependency.
Ep 3 · 8:49
opinion Qualitative MR exocrine assessment appears different between pediatric and adult patients, suggesting possible size or weight dependency.
Ep 3 · 9:41
opinion In chronic or acute recurrent pancreatitis patients with ductal changes, the pancreatic duct is often dilated and abnormal at baseline, so secretin may not be needed to visualize the duct.

Chronic Pancreatitis, Function Tests, & Pain Management: Pancreatic Disease

Ep 6 · 29:42
clinical MR pancreatic function testing (MRPFT) acquires identical fluid-sensitive imaging pre- and post-secretin, then quantifies the volume of fluid secreted into the gastrointestinal tract.
Ep 6 · 29:42
clinical MR pancreatic function testing (MRPFT) acquires identical fluid-sensitive imaging pre- and post-secretin, then quantifies the volume of fluid secreted into the gastrointestinal tract.
Ep 6 · 29:42
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing, is to noninvasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 6 · 29:42
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing, is to noninvasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 6 · 29:53
quote We acquire identical imaging both prior to and following administration of secretin. So there's a question earlier about use of secretin and MRCP. This is our primary means of using Secretin or the main reason that we use Secretin for MRCP.
Ep 6 · 29:53
quote We acquire identical imaging both prior to and following administration of secretin. So there's a question earlier about use of secretin and MRCP. This is our primary means of using Secretin or the main reason that we use Secretin for MRCP.
Ep 6 · 31:02
clinical In the MRPFT protocol, there is about a 15-minute delay between pre- and post-secretin imaging to allow fluid accumulation.
Ep 6 · 31:02
quote The way our protocol is set up, it's about 15 minutes between pre and post. You give the amount, about 15 minutes for that fluid to accumulate.
Ep 6 · 31:02
clinical In the MRPFT protocol, there is about a 15-minute delay between pre- and post-secretin imaging to allow fluid accumulation.
Ep 6 · 31:02
quote The way our protocol is set up, it's about 15 minutes between pre and post. You give the amount, about 15 minutes for that fluid to accumulate.
Ep 6 · 32:13
clinical MRPFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin fluid from post-secretin fluid.
Ep 6 · 32:13
quote You take your pre-image, you quantify your fluid on there, you take your post image, quantify your fluid there, subtract pre from post, and you have your secreted fluid volume in response to secretin.
Ep 6 · 32:13
clinical MRPFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin fluid from post-secretin fluid.
Ep 6 · 32:13
quote You take your pre-image, you quantify your fluid on there, you take your post image, quantify your fluid there, subtract pre from post, and you have your secreted fluid volume in response to secretin.
Ep 6 · 32:43
quote We are looking at that right now. That's, that's the big question. So we've done several steps to get ourselves on the way here. We've proven that we can accurately quantitate fluid.
Ep 6 · 32:43
clinical Correlation between MRPFT volumetric analysis and endoscopic pancreatic function testing is under study in about 35 patients.
Ep 6 · 32:43
clinical Correlation between MRPFT volumetric analysis and endoscopic pancreatic function testing is under study in about 35 patients.
Ep 6 · 32:43
quote We are looking at that right now. That's, that's the big question. So we've done several steps to get ourselves on the way here. We've proven that we can accurately quantitate fluid.
Ep 6 · 33:03
quote We have some preliminary data in about 35 patients where we have been looking at the correlation between the secretin function, the endoscopic pancreatic function testing.
Ep 6 · 33:03
quote We have some preliminary data in about 35 patients where we have been looking at the correlation between the secretin function, the endoscopic pancreatic function testing.
Ep 6 · 33:24
opinion Qualitative assessment of exocrine function by MRPFT may differ between pediatric and adult patients, possibly due to size or weight dependency.
Ep 6 · 33:24
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt. And so it may be that there's a size dependency, a weight dependency, and so we're still figuring those sorts of things out.
Ep 6 · 33:24
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt. And so it may be that there's a size dependency, a weight dependency, and so we're still figuring those sorts of things out.
Ep 6 · 33:24
opinion Qualitative assessment of exocrine function by MRPFT may differ between pediatric and adult patients, possibly due to size or weight dependency.
Ep 6 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, secretin may not add diagnostic value for duct visualization, though it is used primarily for exocrine assessment.
Ep 6 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, secretin may not add diagnostic value for duct visualization, though it is used primarily for exocrine assessment.
Ep 6 · 34:46
quote In a patient with an abnormal duct, does that dilation add anything? I get it. I think there is a subset of patients where it probably does and there's a subset of patients where it probably doesn't, and that still needs to be teased and figured out.
Ep 6 · 34:46
quote In a patient with an abnormal duct, does that dilation add anything? I get it. I think there is a subset of patients where it probably does and there's a subset of patients where it probably doesn't, and that still needs to be teased and figured out.

Acute Pancreatitis

Ep 7 · 2:09
clinical Ultrasound is the initial imaging modality for suspected uncomplicated acute pancreatitis; it is radiation-free and gives a reasonably good look at the pancreas, but is limited for evaluating complications.
Ep 7 · 28:19
clinical For pediatric pancreatitis CT, a portal venous phase is sufficient (no multi-phase needed); oral contrast helps separate fluid-filled bowel from pancreatic fluid collections but is not a deal-breaker if patient cannot tolerate it.
Ep 7 · 29:51
clinical Absent enhancement on contrast-enhanced CT is highly concerning for pancreatic necrosis.
Ep 7 · 29:51
quote when we see absent enhancement like that, that's highly concerning for necrosis within the. Pancreas.
Ep 7 · 42:34
opinion Secretin-enhanced MRCP has unclear added value in pediatric pancreatitis; adult literature data is 'iffy.' In acute recurrent or chronic pancreatitis patients, ducts are often dilated enough to visualize without secretin.

Function Tests & Pain Management: Pancreatic Disease

Ep 1 · 5:07
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing is to non-invasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 1 · 5:18
clinical MR pancreatic function testing acquires identical imaging pre- and post-secretin to quantify the volume of fluid secreted into the gastrointestinal tract.
Ep 1 · 6:27
clinical The delay between pre- and post-secretin MR imaging is about 15 minutes to allow fluid accumulation.
Ep 1 · 7:38
clinical MR-PFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin from post-secretin fluid volume.
Ep 1 · 8:13
quote We've proven that we can accurately quantitate fluid by measuring phantoms, so you can put phantoms in the MR scanner and you can prove that you can actually quantitate the fluid.
Ep 1 · 8:13
clinical Phantom studies have proven that MR can accurately quantitate fluid volume.
Ep 1 · 8:28
clinical Preliminary data in about 35 patients are examining correlation between MR-PFT and endoscopic pancreatic function testing.
Ep 1 · 8:49
opinion Qualitative MR exocrine assessment appears different between pediatric and adult patients, suggesting possible size or weight dependency.
Ep 1 · 8:49
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt, and so it may be that there's a size dependency, a weight dependency.
Ep 1 · 9:41
opinion In chronic or acute recurrent pancreatitis patients with ductal changes, the pancreatic duct is often dilated and abnormal at baseline, so secretin may not be needed to visualize the duct.

Chronic Pancreatitis, Function Tests, & Pain Management: Pancreatic Disease

Ep 2 · 29:42
clinical MR pancreatic function testing (MRPFT) acquires identical fluid-sensitive imaging pre- and post-secretin, then quantifies the volume of fluid secreted into the gastrointestinal tract.
Ep 2 · 29:42
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing, is to noninvasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 2 · 29:42
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing, is to noninvasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 2 · 29:42
clinical MR pancreatic function testing (MRPFT) acquires identical fluid-sensitive imaging pre- and post-secretin, then quantifies the volume of fluid secreted into the gastrointestinal tract.
Ep 2 · 29:53
quote We acquire identical imaging both prior to and following administration of secretin. So there's a question earlier about use of secretin and MRCP. This is our primary means of using Secretin or the main reason that we use Secretin for MRCP.
Ep 2 · 29:53
quote We acquire identical imaging both prior to and following administration of secretin. So there's a question earlier about use of secretin and MRCP. This is our primary means of using Secretin or the main reason that we use Secretin for MRCP.
Ep 2 · 31:02
quote The way our protocol is set up, it's about 15 minutes between pre and post. You give the amount, about 15 minutes for that fluid to accumulate.
Ep 2 · 31:02
clinical In the MRPFT protocol, there is about a 15-minute delay between pre- and post-secretin imaging to allow fluid accumulation.
Ep 2 · 31:02
clinical In the MRPFT protocol, there is about a 15-minute delay between pre- and post-secretin imaging to allow fluid accumulation.
Ep 2 · 31:02
quote The way our protocol is set up, it's about 15 minutes between pre and post. You give the amount, about 15 minutes for that fluid to accumulate.
Ep 2 · 32:13
clinical MRPFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin fluid from post-secretin fluid.
Ep 2 · 32:13
quote You take your pre-image, you quantify your fluid on there, you take your post image, quantify your fluid there, subtract pre from post, and you have your secreted fluid volume in response to secretin.
Ep 2 · 32:13
quote You take your pre-image, you quantify your fluid on there, you take your post image, quantify your fluid there, subtract pre from post, and you have your secreted fluid volume in response to secretin.
Ep 2 · 32:13
clinical MRPFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin fluid from post-secretin fluid.
Ep 2 · 32:43
clinical Correlation between MRPFT volumetric analysis and endoscopic pancreatic function testing is under study in about 35 patients.
Ep 2 · 32:43
clinical Correlation between MRPFT volumetric analysis and endoscopic pancreatic function testing is under study in about 35 patients.
Ep 2 · 32:43
quote We are looking at that right now. That's, that's the big question. So we've done several steps to get ourselves on the way here. We've proven that we can accurately quantitate fluid.
Ep 2 · 32:43
quote We are looking at that right now. That's, that's the big question. So we've done several steps to get ourselves on the way here. We've proven that we can accurately quantitate fluid.
Ep 2 · 33:03
quote We have some preliminary data in about 35 patients where we have been looking at the correlation between the secretin function, the endoscopic pancreatic function testing.
Ep 2 · 33:03
quote We have some preliminary data in about 35 patients where we have been looking at the correlation between the secretin function, the endoscopic pancreatic function testing.
Ep 2 · 33:24
opinion Qualitative assessment of exocrine function by MRPFT may differ between pediatric and adult patients, possibly due to size or weight dependency.
Ep 2 · 33:24
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt. And so it may be that there's a size dependency, a weight dependency, and so we're still figuring those sorts of things out.
Ep 2 · 33:24
opinion Qualitative assessment of exocrine function by MRPFT may differ between pediatric and adult patients, possibly due to size or weight dependency.
Ep 2 · 33:24
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt. And so it may be that there's a size dependency, a weight dependency, and so we're still figuring those sorts of things out.
Ep 2 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, secretin may not add diagnostic value for duct visualization, though it is used primarily for exocrine assessment.
Ep 2 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, secretin may not add diagnostic value for duct visualization, though it is used primarily for exocrine assessment.
Ep 2 · 34:46
quote In a patient with an abnormal duct, does that dilation add anything? I get it. I think there is a subset of patients where it probably does and there's a subset of patients where it probably doesn't, and that still needs to be teased and figured out.
Ep 2 · 34:46
quote In a patient with an abnormal duct, does that dilation add anything? I get it. I think there is a subset of patients where it probably does and there's a subset of patients where it probably doesn't, and that still needs to be teased and figured out.

Chronic Pancreatitis - Pancreatic Pathologies by Cincinnati Children's Pancreas Care Center

Ep 7 · 2:15
clinical For CT imaging of chronic pancreatitis, a single phase with portal venous contrast is adequate.
Ep 7 · 2:19
quote MRI has advantages over CT in terms of the soft tissue contrast that you get with the multiple different MRI sequences, and Going to provide you the best visualization of both parenchymal and duct changes that we see with chronic pancreatitis.
Ep 7 · 2:19
clinical MRI has advantages over CT in terms of soft tissue contrast from multiple different MRI sequences, providing the best visualization of both parenchymal and duct changes in chronic pancreatitis.
Ep 7 · 2:50
quote And non-contrast CT is essentially never needed in a child with pancreatitis.
Ep 7 · 2:50
clinical Non-contrast CT is essentially never needed in a child with pancreatitis because calcifications can be seen on post-contrast phases of imaging.
Ep 7 · 3:13
clinical The key MRI sequences for chronic pancreatitis are the 3D MRCP sequence to characterize the duct and its relationship to the bile duct, and a T1 weighted sequence to understand parenchymal health.

Acute Pancreatitis

Ep 12 · 2:09
clinical Ultrasound is the initial imaging modality for suspected uncomplicated acute pancreatitis in children because it is radiation-free and gives a reasonably good look at the pancreas.
Ep 12 · 25:33
clinical The pancreas can be difficult to visualize on ultrasound in larger patients, in patients who are not NPO (stomach full of gas), or when there is ileus from inflammation; bowel gas affects ultrasound wave penetration.
Ep 12 · 25:35
quote the pancreas can be a little bit difficult to see sometimes. Especially in larger patients
Ep 12 · 28:19
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients as the goal is to identify complications (venous thrombosis, necrosis, fluid collections), not masses.
Ep 12 · 28:41
clinical Oral contrast is helpful in CT of pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but a sick patient who cannot tolerate oral contrast can still have an informative CT without it.
Ep 12 · 29:51
clinical On contrast-enhanced CT, absent enhancement in pancreatic tissue is highly concerning for necrosis.
Ep 12 · 34:03
clinical In MRI of the pancreas after acute attacks have resolved, a prominent pancreatic duct (visible as a white stripe) and some atrophy/irregularity of contour may be seen, but these findings alone are not diagnostic of chronic pancreatitis.
Ep 12 · 42:34
clinical Evidence for secretin-enhanced MRCP in pediatric pancreatitis is limited; even adult literature shows iffy data on added value, though it may improve visualization of ductal anomalies in some cases.
Ep 12 · 42:49
quote when you have it's. Often in the chronic pancreatitic patients or the acute recurrence that we're doing these MR exams and they've had enough attacks that generally the ducts dilated and you can see it without secretin

Function Tests & Pain Management: Pancreatic Disease

Ep 15 · 5:07
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing is to non-invasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 15 · 5:07
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing is to non-invasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 15 · 5:18
clinical MR pancreatic function testing acquires identical imaging pre- and post-secretin to quantify the volume of fluid secreted into the gastrointestinal tract.
Ep 15 · 5:18
clinical MR pancreatic function testing acquires identical imaging pre- and post-secretin to quantify the volume of fluid secreted into the gastrointestinal tract.
Ep 15 · 6:27
clinical The delay between pre- and post-secretin MR imaging is about 15 minutes to allow fluid accumulation.
Ep 15 · 6:27
clinical The delay between pre- and post-secretin MR imaging is about 15 minutes to allow fluid accumulation.
Ep 15 · 7:38
clinical MR-PFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin from post-secretin fluid volume.
Ep 15 · 7:38
clinical MR-PFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin from post-secretin fluid volume.
Ep 15 · 8:13
clinical Phantom studies have proven that MR can accurately quantitate fluid volume.
Ep 15 · 8:13
quote We've proven that we can accurately quantitate fluid by measuring phantoms, so you can put phantoms in the MR scanner and you can prove that you can actually quantitate the fluid.
Ep 15 · 8:13
quote We've proven that we can accurately quantitate fluid by measuring phantoms, so you can put phantoms in the MR scanner and you can prove that you can actually quantitate the fluid.
Ep 15 · 8:13
clinical Phantom studies have proven that MR can accurately quantitate fluid volume.
Ep 15 · 8:28
clinical Preliminary data in about 35 patients are examining correlation between MR-PFT and endoscopic pancreatic function testing.
Ep 15 · 8:28
clinical Preliminary data in about 35 patients are examining correlation between MR-PFT and endoscopic pancreatic function testing.
Ep 15 · 8:49
opinion Qualitative MR exocrine assessment appears different between pediatric and adult patients, suggesting possible size or weight dependency.
Ep 15 · 8:49
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt, and so it may be that there's a size dependency, a weight dependency.
Ep 15 · 8:49
opinion Qualitative MR exocrine assessment appears different between pediatric and adult patients, suggesting possible size or weight dependency.
Ep 15 · 8:49
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt, and so it may be that there's a size dependency, a weight dependency.
Ep 15 · 9:41
opinion In chronic or acute recurrent pancreatitis patients with ductal changes, the pancreatic duct is often dilated and abnormal at baseline, so secretin may not be needed to visualize the duct.
Ep 15 · 9:41
opinion In chronic or acute recurrent pancreatitis patients with ductal changes, the pancreatic duct is often dilated and abnormal at baseline, so secretin may not be needed to visualize the duct.
Pancreatitis 84 entries

Acute Pancreatitis

Ep 2 · 2:09
clinical Ultrasound is the initial imaging modality for suspected uncomplicated acute pancreatitis in children because it is radiation-free and gives a reasonably good look at the pancreas.
Ep 2 · 25:33
clinical The pancreas can be difficult to visualize on ultrasound in larger patients, in patients who are not NPO (stomach full of gas), or when there is ileus from inflammation; bowel gas affects ultrasound wave penetration.
Ep 2 · 25:35
quote the pancreas can be a little bit difficult to see sometimes. Especially in larger patients
Ep 2 · 28:19
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients as the goal is to identify complications (venous thrombosis, necrosis, fluid collections), not masses.
Ep 2 · 28:41
clinical Oral contrast is helpful in CT of pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but a sick patient who cannot tolerate oral contrast can still have an informative CT without it.
Ep 2 · 29:51
clinical On contrast-enhanced CT, absent enhancement in pancreatic tissue is highly concerning for necrosis.
Ep 2 · 34:03
clinical In MRI of the pancreas after acute attacks have resolved, a prominent pancreatic duct (visible as a white stripe) and some atrophy/irregularity of contour may be seen, but these findings alone are not diagnostic of chronic pancreatitis.
Ep 2 · 42:34
clinical Evidence for secretin-enhanced MRCP in pediatric pancreatitis is limited; even adult literature shows iffy data on added value, though it may improve visualization of ductal anomalies in some cases.
Ep 2 · 42:49
quote when you have it's. Often in the chronic pancreatitic patients or the acute recurrence that we're doing these MR exams and they've had enough attacks that generally the ducts dilated and you can see it without secretin

Acute and Acute Recurrent Pancreatitis: Pancreatic Disease

Ep 6 · 3:43
clinical Ultrasound should be the initial imaging modality for suspected uncomplicated acute pancreatitis because it is radiation-free and provides a reasonably good look at the pancreas.
Ep 6 · 3:43
clinical Ultrasound should be the initial imaging modality for suspected uncomplicated acute pancreatitis because it is radiation-free and provides a reasonably good look at the pancreas.
Ep 6 · 27:42
quote I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 6 · 27:42
quote I mean unfortunately the pancreas can be a little bit difficult to see sometimes. Especially in larger patients and as you say, in patients that are NPO, if you've got a stomach full of gas or if you have an ileus because there's a real inflammatory process going on, all that bowel gas can really affect the penetration of the ultrasound waves and make the pancreas non-visible.
Ep 6 · 33:31
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients unless evaluating for masses.
Ep 6 · 33:31
clinical For CT imaging of acute pancreatitis, a single portal venous phase is sufficient; multi-phase imaging is not needed in pediatric patients unless evaluating for masses.
Ep 6 · 33:50
clinical Oral contrast is helpful in CT for pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but the exam can provide substantial information without it if the patient cannot tolerate oral contrast.
Ep 6 · 33:50
clinical Oral contrast is helpful in CT for pancreatitis to separate fluid-filled bowel loops from pancreatic fluid collections, but the exam can provide substantial information without it if the patient cannot tolerate oral contrast.
Ep 6 · 45:01
opinion The added value of secretin-enhanced MRCP in pediatric pancreatitis is not well established; even adult literature shows limited evidence, though it may improve visualization of ductal anomalies in select cases.
Ep 6 · 45:01
opinion The added value of secretin-enhanced MRCP in pediatric pancreatitis is not well established; even adult literature shows limited evidence, though it may improve visualization of ductal anomalies in select cases.

Function Tests & Pain Management: Pancreatic Disease

Ep 3 · 5:07
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing is to non-invasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 3 · 5:07
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing is to non-invasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 3 · 5:18
clinical MR pancreatic function testing acquires identical imaging pre- and post-secretin to quantify the volume of fluid secreted into the gastrointestinal tract.
Ep 3 · 5:18
clinical MR pancreatic function testing acquires identical imaging pre- and post-secretin to quantify the volume of fluid secreted into the gastrointestinal tract.
Ep 3 · 6:27
clinical The delay between pre- and post-secretin MR imaging is about 15 minutes to allow fluid accumulation.
Ep 3 · 6:27
clinical The delay between pre- and post-secretin MR imaging is about 15 minutes to allow fluid accumulation.
Ep 3 · 7:38
clinical MR-PFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin from post-secretin fluid volume.
Ep 3 · 7:38
clinical MR-PFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin from post-secretin fluid volume.
Ep 3 · 8:13
clinical Phantom studies have proven that MR can accurately quantitate fluid volume.
Ep 3 · 8:13
quote We've proven that we can accurately quantitate fluid by measuring phantoms, so you can put phantoms in the MR scanner and you can prove that you can actually quantitate the fluid.
Ep 3 · 8:13
clinical Phantom studies have proven that MR can accurately quantitate fluid volume.
Ep 3 · 8:13
quote We've proven that we can accurately quantitate fluid by measuring phantoms, so you can put phantoms in the MR scanner and you can prove that you can actually quantitate the fluid.
Ep 3 · 8:28
clinical Preliminary data in about 35 patients are examining correlation between MR-PFT and endoscopic pancreatic function testing.
Ep 3 · 8:28
clinical Preliminary data in about 35 patients are examining correlation between MR-PFT and endoscopic pancreatic function testing.
Ep 3 · 8:49
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt, and so it may be that there's a size dependency, a weight dependency.
Ep 3 · 8:49
opinion Qualitative MR exocrine assessment appears different between pediatric and adult patients, suggesting possible size or weight dependency.
Ep 3 · 8:49
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt, and so it may be that there's a size dependency, a weight dependency.
Ep 3 · 8:49
opinion Qualitative MR exocrine assessment appears different between pediatric and adult patients, suggesting possible size or weight dependency.
Ep 3 · 9:41
opinion In chronic or acute recurrent pancreatitis patients with ductal changes, the pancreatic duct is often dilated and abnormal at baseline, so secretin may not be needed to visualize the duct.
Ep 3 · 9:41
opinion In chronic or acute recurrent pancreatitis patients with ductal changes, the pancreatic duct is often dilated and abnormal at baseline, so secretin may not be needed to visualize the duct.

Chronic Pancreatitis, Function Tests, & Pain Management: Pancreatic Disease

Ep 4 · 29:42
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing, is to noninvasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 4 · 29:42
clinical MR pancreatic function testing (MRPFT) acquires identical fluid-sensitive imaging pre- and post-secretin, then quantifies the volume of fluid secreted into the gastrointestinal tract.
Ep 4 · 29:42
quote What we're trying to do here at Cincinnati Children's with the MRPFTs or MR pancreatic function testing, is to noninvasively accomplish or at least simulate what's going on with the endoscopic pancreatic function testing.
Ep 4 · 29:42
clinical MR pancreatic function testing (MRPFT) acquires identical fluid-sensitive imaging pre- and post-secretin, then quantifies the volume of fluid secreted into the gastrointestinal tract.
Ep 4 · 29:53
quote We acquire identical imaging both prior to and following administration of secretin. So there's a question earlier about use of secretin and MRCP. This is our primary means of using Secretin or the main reason that we use Secretin for MRCP.
Ep 4 · 29:53
quote We acquire identical imaging both prior to and following administration of secretin. So there's a question earlier about use of secretin and MRCP. This is our primary means of using Secretin or the main reason that we use Secretin for MRCP.
Ep 4 · 31:02
clinical In the MRPFT protocol, there is about a 15-minute delay between pre- and post-secretin imaging to allow fluid accumulation.
Ep 4 · 31:02
quote The way our protocol is set up, it's about 15 minutes between pre and post. You give the amount, about 15 minutes for that fluid to accumulate.
Ep 4 · 31:02
clinical In the MRPFT protocol, there is about a 15-minute delay between pre- and post-secretin imaging to allow fluid accumulation.
Ep 4 · 31:02
quote The way our protocol is set up, it's about 15 minutes between pre and post. You give the amount, about 15 minutes for that fluid to accumulate.
Ep 4 · 32:13
clinical MRPFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin fluid from post-secretin fluid.
Ep 4 · 32:13
clinical MRPFT can threshold images and quantify secreted fluid volume by subtracting pre-secretin fluid from post-secretin fluid.
Ep 4 · 32:13
quote You take your pre-image, you quantify your fluid on there, you take your post image, quantify your fluid there, subtract pre from post, and you have your secreted fluid volume in response to secretin.
Ep 4 · 32:13
quote You take your pre-image, you quantify your fluid on there, you take your post image, quantify your fluid there, subtract pre from post, and you have your secreted fluid volume in response to secretin.
Ep 4 · 32:43
quote We are looking at that right now. That's, that's the big question. So we've done several steps to get ourselves on the way here. We've proven that we can accurately quantitate fluid.
Ep 4 · 32:43
quote We are looking at that right now. That's, that's the big question. So we've done several steps to get ourselves on the way here. We've proven that we can accurately quantitate fluid.
Ep 4 · 32:43
clinical Correlation between MRPFT volumetric analysis and endoscopic pancreatic function testing is under study in about 35 patients.
Ep 4 · 32:43
clinical Correlation between MRPFT volumetric analysis and endoscopic pancreatic function testing is under study in about 35 patients.
Ep 4 · 33:03
quote We have some preliminary data in about 35 patients where we have been looking at the correlation between the secretin function, the endoscopic pancreatic function testing.
Ep 4 · 33:03
quote We have some preliminary data in about 35 patients where we have been looking at the correlation between the secretin function, the endoscopic pancreatic function testing.
Ep 4 · 33:24
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt. And so it may be that there's a size dependency, a weight dependency, and so we're still figuring those sorts of things out.
Ep 4 · 33:24
opinion Qualitative assessment of exocrine function by MRPFT may differ between pediatric and adult patients, possibly due to size or weight dependency.
Ep 4 · 33:24
quote The qualitative assessment seems to be different between pediatric and adult patients, at least in my gestalt. And so it may be that there's a size dependency, a weight dependency, and so we're still figuring those sorts of things out.
Ep 4 · 33:24
opinion Qualitative assessment of exocrine function by MRPFT may differ between pediatric and adult patients, possibly due to size or weight dependency.
Ep 4 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, secretin may not add diagnostic value for duct visualization, though it is used primarily for exocrine assessment.
Ep 4 · 34:15
opinion In chronic pancreatitis patients with dilated and abnormal ducts at baseline, secretin may not add diagnostic value for duct visualization, though it is used primarily for exocrine assessment.
Ep 4 · 34:46
quote In a patient with an abnormal duct, does that dilation add anything? I get it. I think there is a subset of patients where it probably does and there's a subset of patients where it probably doesn't, and that still needs to be teased and figured out.
Ep 4 · 34:46
quote In a patient with an abnormal duct, does that dilation add anything? I get it. I think there is a subset of patients where it probably does and there's a subset of patients where it probably doesn't, and that still needs to be teased and figured out.

Acute Pancreatitis

Ep 12 · 2:09
clinical Ultrasound is the initial imaging modality for suspected uncomplicated acute pancreatitis; it is radiation-free and gives a reasonably good look at the pancreas, but is limited for evaluating complications.
Ep 12 · 28:19
clinical For pediatric pancreatitis CT, a portal venous phase is sufficient (no multi-phase needed); oral contrast helps separate fluid-filled bowel from pancreatic fluid collections but is not a deal-breaker if patient cannot tolerate it.
Ep 12 · 29:51
quote when we see absent enhancement like that, that's highly concerning for necrosis within the. Pancreas.
Ep 12 · 29:51
clinical Absent enhancement on contrast-enhanced CT is highly concerning for pancreatic necrosis.
Ep 12 · 42:34
opinion Secretin-enhanced MRCP has unclear added value in pediatric pancreatitis; adult literature data is 'iffy.' In acute recurrent or chronic pancreatitis patients, ducts are often dilated enough to visualize without secretin.

Chronic Pancreatitis - Pancreatic Pathologies by Cincinnati Children's Pancreas Care Center

Ep 20 · 2:15
clinical For CT imaging of chronic pancreatitis, a single phase with portal venous contrast is adequate.
Ep 20 · 2:15
clinical For CT imaging of chronic pancreatitis, a single phase with portal venous contrast is adequate.
Ep 20 · 2:19
clinical MRI has advantages over CT in terms of soft tissue contrast from multiple different MRI sequences, providing the best visualization of both parenchymal and duct changes in chronic pancreatitis.
Ep 20 · 2:19
clinical MRI has advantages over CT in terms of soft tissue contrast from multiple different MRI sequences, providing the best visualization of both parenchymal and duct changes in chronic pancreatitis.
Ep 20 · 2:19
quote MRI has advantages over CT in terms of the soft tissue contrast that you get with the multiple different MRI sequences, and Going to provide you the best visualization of both parenchymal and duct changes that we see with chronic pancreatitis.
Ep 20 · 2:19
quote MRI has advantages over CT in terms of the soft tissue contrast that you get with the multiple different MRI sequences, and Going to provide you the best visualization of both parenchymal and duct changes that we see with chronic pancreatitis.
Ep 20 · 2:50
quote And non-contrast CT is essentially never needed in a child with pancreatitis.
Ep 20 · 2:50
quote And non-contrast CT is essentially never needed in a child with pancreatitis.
Ep 20 · 2:50
clinical Non-contrast CT is essentially never needed in a child with pancreatitis because calcifications can be seen on post-contrast phases of imaging.
Ep 20 · 2:50
clinical Non-contrast CT is essentially never needed in a child with pancreatitis because calcifications can be seen on post-contrast phases of imaging.
Ep 20 · 3:13
clinical The key MRI sequences for chronic pancreatitis are the 3D MRCP sequence to characterize the duct and its relationship to the bile duct, and a T1 weighted sequence to understand parenchymal health.
Ep 20 · 3:13
clinical The key MRI sequences for chronic pancreatitis are the 3D MRCP sequence to characterize the duct and its relationship to the bile duct, and a T1 weighted sequence to understand parenchymal health.