Anfleur von Hall

32 statements · 2 topics

Featured statements

stricture formation remains the most frequent post-operative complication in more than half of the cases.
quote · Esophageal Atresia
Stricture formation remains the most frequent post-operative complication in more than half of the cases of esophageal atresia.
epidemiological · Esophageal Atresia
Steroids inhibit the formation of collagen, enhance its breakdown, and decrease fibrotic healing in esophageal strictures.
clinical · Esophageal Stricture
The standard treatment for esophageal stricture is endoscopic dilatation either by bouginage or by balloon dilatation.
clinical · Esophageal Stricture

Nothing matches these filters — clear the search or widen the filters.

Anfleur's statements about Esophageal Atresia 16 statements

Open the Esophageal Atresia collection →

STEPS-EA trial: Esophageal Atresia

Quotation Hello, my name is Anfleur von Hall, and I'm one of the coordinating investigators of the SECA trial. Open
Quotation The SEP CA trial stands for intralesional steroid injections to prevent refractory strictures in patients with esophageal atresia and is an international multi-center randomized control trial. Open
Statement The standard treatment for esophageal atresia is surgery with an end to end anastomosis to restore continuity. Open
Statement Stricture formation remains the most frequent post-operative complication in more than half of the cases of esophageal atresia. Open
Quotation stricture formation remains the most frequent post-operative complication in more than half of the cases. Open
Statement The standard treatment for esophageal stricture is endoscopic dilatation either by bouginage or by balloon dilatation. Open
Statement Worldwide, the balloon is most frequently used for esophageal stricture dilatation. Open
Statement Intralesional steroid injections use triamcinolone (Kenalog) as the most common agent. Open
Quotation It is thought that these steroids inhibit the formation of collagen, enhances its breakdown, and decreases the fibrotic healing. Open
Statement Steroids inhibit the formation of collagen, enhance its breakdown, and decrease fibrotic healing in esophageal strictures. Open
Statement Each of the four quadrants of the esophageal stricture is injected with steroid in the STEPS-EA protocol. Open
Statement 110 children born with esophageal atresia are needed to prove the effectiveness of the steroid injection. Open
Statement Study Group A will be injected with triamcinolone and then undergo balloon dilatation, while Study Group B will only undergo balloon dilatation. Open
Statement A second esophagram will be performed to objectify the effectiveness of the intervention on the length and diameter of the stricture. Open
Statement Physical length and weight will be measured at 4 time points throughout the 6 month study period to investigate possible systemic side effects of steroid injection. Open
Statement A hair sample will be collected at the end of the follow-up period to measure cortisol levels to investigate possible systemic effects of intralesional steroid injection. Open
Anfleur's statements about Esophageal Stricture 16 statements

Open the Esophageal Stricture collection →

STEPS-EA trial: Esophageal Atresia

Quotation Hello, my name is Anfleur von Hall, and I'm one of the coordinating investigators of the SECA trial. Open
Quotation The SEP CA trial stands for intralesional steroid injections to prevent refractory strictures in patients with esophageal atresia and is an international multi-center randomized control trial. Open
Statement The standard treatment for esophageal atresia is surgery with an end to end anastomosis to restore continuity. Open
Statement Stricture formation remains the most frequent post-operative complication in more than half of the cases of esophageal atresia. Open
Quotation stricture formation remains the most frequent post-operative complication in more than half of the cases. Open
Statement The standard treatment for esophageal stricture is endoscopic dilatation either by bouginage or by balloon dilatation. Open
Statement Worldwide, the balloon is most frequently used for esophageal stricture dilatation. Open
Statement Intralesional steroid injections use triamcinolone (Kenalog) as the most common agent. Open
Statement Steroids inhibit the formation of collagen, enhance its breakdown, and decrease fibrotic healing in esophageal strictures. Open
Quotation It is thought that these steroids inhibit the formation of collagen, enhances its breakdown, and decreases the fibrotic healing. Open
Statement Each of the four quadrants of the esophageal stricture is injected with steroid in the STEPS-EA protocol. Open
Statement 110 children born with esophageal atresia are needed to prove the effectiveness of the steroid injection. Open
Statement Study Group A will be injected with triamcinolone and then undergo balloon dilatation, while Study Group B will only undergo balloon dilatation. Open
Statement A second esophagram will be performed to objectify the effectiveness of the intervention on the length and diameter of the stricture. Open
Statement Physical length and weight will be measured at 4 time points throughout the 6 month study period to investigate possible systemic side effects of steroid injection. Open
Statement A hair sample will be collected at the end of the follow-up period to measure cortisol levels to investigate possible systemic effects of intralesional steroid injection. Open