Erin Keena
31 statements · 1 topic
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when cases develop new intraoperative neurological deficits, 90% of these are occurring during the subcortical dissection
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Craniopharyngioma
children are not just miniature adults
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Craniopharyngioma
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Erin's statements about Craniopharyngioma 31 statements
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Minimally Disruptive Subcortical Neurosurgery in Children - Concepts of the...
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The immature pediatric brain is still undergoing myelination, and while cells may be more vulnerable to injury, there is ongoing neuroplasticity, synaptogenesis, and synaptic pruning allowing for unique recovery from surgery.
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Over 80% of pediatric brain tumors are curable, including both benign and malignant tumors.
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the most inspiring thing about pediatric brain tumors is that over 80% of them are curable
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Modern WHO guidelines now include genomic and molecular analysis requirements for multiple tumor types, necessitating adequate tissue preservation.
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All brain tissue is relevant; there is not just eloquent and non-eloquent cortex, and all fiber tracts en route to lesions must be preserved regardless of corridor.
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all tissue is relevant, that there's not just eloquent cortex and non-eloquent cortex
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From awake craniotomy data, 90% of new intraoperative neurological deficits occur during subcortical dissection.
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when cases develop new intraoperative neurological deficits, 90% of these are occurring during the subcortical dissection
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A parafascicular trajectory minimizes shear forces applied to white matter tracts by running parallel to the main white matter tracts.
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A trans-sulcal route with parafascicular trajectory reduces the amount of brain traversed en route to reach lesions.
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Using a tubular retractor distributes forces radially, thereby protecting displaced tissue rather than simply retracting with malleable retractors.
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Traditional craniotomies can cause brain collapse in children with large ventricles after corpus callosotomy, leading to CSF egress into subdural space, pseudomeningocele development, and prolonged recoveries.
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Pure endoscopic resection is limited by inability to achieve simultaneous hemostasis, restriction to one-handed technique, poor retraction capability, and requirement to remove tumor in very small pieces or morsellate with devices.
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BrainPath approach requires a small craniotomy 2.5 to 3 centimeters in diameter and has a slightly restrictive field requiring extra-long keyhole instruments.
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The port cannot be moved around significantly once in place or it will disrupt fiber tracts.
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Ideal BrainPath cases are lesions less than 4 centimeters that can be accessed down the long axis through a parafascicular corridor, including subcortical, deep, or metastatic lesions.
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Removing choroid plexus tumors en bloc with BrainPath preserves the architecture for pathologists to make critical diagnoses, unlike morsellation into small pieces.
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In Dr. Keena's personal series, mean operative time was 3 hours and 11 minutes with median length of stay of 48 hours.
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In Dr. Keena's personal series, extent of resection matched intended resection in every case.
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In Dr. Keena's personal series, all patients were neurologically intact with the exception of one pre-existing visual field deficit.
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the way I removed tumors 5 years ago will not be how I remove one in the next 5 years
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BrainPath resection is safe and efficacious with similar or improved outcomes and shorter lengths of stay compared to traditional approaches.
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The broader BrainPath series includes over 200 cases used throughout the brain, predominantly for supratentorial indications including primary tumors and metastases.
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The exoscope provides more options for patient head positioning and approach angle compared to the microscope, which requires careful positioning so the port is as superior as possible for ergonomic downward viewing.
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The Nico Myriad preserves tissue architecture by morsellating tissue and provides the smallest obstruction in the surgical view due to its streamlined handpiece.
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For trans-sulcal BrainPath passage, the arachnoid is opened up to about 2 centimeters (though only 15mm is needed), then the patient is placed under Valsalva without mannitol or CSF pressure relief, the opening is widened with bipolar tips, and the blunt trocar is passed under navigation.
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it's really important not to give these patients any manitol, not to relieve the CSF pressure first
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I haven't hit any major vessels, and I think it is because it's a blunt tip and it radially, it, it allows the vessel to roll off of it
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The blunt tip of the BrainPath trocar allows vessels to roll off radially, and Dr. Keena has not ruptured any veins or arteries using this technique.
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