the risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.
the risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.
the risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.
the risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.
the risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.
the risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.
epidemiological5–15% of patients who have catheters removed require some additional intervention (enlarging incision, venotomy, or interventional radiology).↗
▶Ep 1 · 0:32
epidemiological0.2–2% of catheter removals result in at least part of the catheter being left behind.↗
▶Ep 1 · 0:32
quotein a couple case the looking retrospectively at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 1 · 0:32
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 1 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 1 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infusion through the line, indwelling duration longer than about 1.5 years, and polyurethane catheter material compared with silicone.↗
▶Ep 1 · 1:31
opinionFor long-term chemotherapy access, a silastic line should be considered instead of a polyurethane line.↗
▶Ep 1 · 2:04
quotein an interventional radiology case series, when they tried to go and endovascularly remove the catheters, there was a risk of the line completely breaking and embolizing distally or of thrombosis occurring during the procedure.↗
▶Ep 1 · 2:04
quoteIf you surgically, if you're gonna go in for an immunotomy, tug at the catheter, you run into a risk of bleeding.↗
▶Ep 1 · 2:04
clinicalSurgical venotomy to retrieve a retained catheter carries a risk of bleeding.↗
▶Ep 1 · 2:04
clinicalEndovascular retrieval by interventional radiology carries risks of the line completely breaking and embolizing distally or of thrombosis occurring during the procedure.↗
Retained Central Venous Catheters
▶Ep 2 · 0:32
epidemiological5 to 15% of patients who have catheters removed require some sort of additional intervention to remove the catheter.↗
▶Ep 2 · 0:32
quotein a couple case the looking retrospectively at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 2 · 0:32
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 2 · 0:32
epidemiologicalThe actual number of catheters or catheter fragments that get left behind is 0.2 to 2%.↗
▶Ep 2 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 2 · 1:12
clinicalRisk factors for catheter retention include catheters that are indwelling for longer than about a year and a half.↗
▶Ep 2 · 1:12
clinicalThere is an association between polyurethane catheter material and catheter retention when compared with silicone catheters.↗
▶Ep 2 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infused through the lines.↗
▶Ep 2 · 1:31
opinionFor long-term chemotherapy, a silastic line should be considered instead of a polyurethane line.↗
▶Ep 2 · 1:42
quoteWe should be considering maybe a silastic line instead of a polyurethane line.↗
▶Ep 2 · 2:04
clinicalIf you surgically go in for a venotomy and tug at the catheter, you run a risk of bleeding.↗
▶Ep 2 · 2:04
clinicalIn interventional radiology retrieval, there is a risk of the line completely breaking and embolizing distally or of thrombosis occurring during the procedure.↗
▶Ep 2 · 2:04
quoteIf you surgically, if you're gonna go in for an immunotomy, tug at the catheter, you run into a risk of bleeding.↗
Management of Retained Central Venous Catheters
▶Ep 3 · 0:32
quotein a couple case series looking retrospectively uh at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 3 · 0:32
epidemiological5 to 15% of patients who have catheters removed require some sort of additional intervention to remove the catheter.↗
▶Ep 3 · 0:57
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 3 · 0:57
epidemiologicalThe actual number of catheters or catheter fragments that get left behind is 0.2 to 2%.↗
▶Ep 3 · 1:12
clinicalRisk factors for catheter retention include catheters that are indwelling for longer than about a year and a half.↗
▶Ep 3 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 3 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infusion through the line.↗
▶Ep 3 · 1:25
clinicalThere is an association between polyurethane catheter material and catheter retention when compared with silicone catheters.↗
▶Ep 3 · 1:46
guidelineThe recommendation would be to go with silastic catheters for long-term chemotherapy cases.↗
▶Ep 3 · 2:10
clinicalSurgical venotomy to retrieve a retained catheter carries a risk of bleeding.↗
▶Ep 3 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of the line completely breaking and embolizing distally.↗
▶Ep 3 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of thrombosis occurring during the procedure.↗
▶Ep 3 · 2:31
quotewhenever multiple studies which have looked at patients who actually had retained catheter fragments in follow-up periods from months to the order of 5 years, there weren't any complications. So, no thrombosis associated with the line. Fragments and no infections.↗
▶Ep 3 · 2:31
epidemiologicalMultiple studies of patients with retained catheter fragments, with follow-up periods from months to the order of 5 years, found no complications.↗
▶Ep 3 · 2:42
epidemiologicalNo thrombosis was associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
▶Ep 3 · 2:42
epidemiologicalNo infections were associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 1 · 0:32
quotein a couple case the looking retrospectively at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 1 · 0:32
epidemiological5–15% of patients who have catheters removed require some additional intervention (enlarging incision, venotomy, or interventional radiology).↗
▶Ep 1 · 0:32
epidemiological0.2–2% of catheter removals result in at least part of the catheter being left behind.↗
▶Ep 1 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 1 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infusion through the line, indwelling duration longer than about 1.5 years, and polyurethane catheter material compared with silicone.↗
▶Ep 1 · 1:31
opinionFor long-term chemotherapy access, a silastic line should be considered instead of a polyurethane line.↗
▶Ep 1 · 2:04
clinicalEndovascular retrieval by interventional radiology carries risks of the line completely breaking and embolizing distally or of thrombosis occurring during the procedure.↗
▶Ep 1 · 2:04
clinicalSurgical venotomy to retrieve a retained catheter carries a risk of bleeding.↗
▶Ep 1 · 2:04
quotein an interventional radiology case series, when they tried to go and endovascularly remove the catheters, there was a risk of the line completely breaking and embolizing distally or of thrombosis occurring during the procedure.↗
▶Ep 1 · 2:04
quoteIf you surgically, if you're gonna go in for an immunotomy, tug at the catheter, you run into a risk of bleeding.↗
Retained Central Venous Catheters
▶Ep 2 · 0:32
epidemiological5 to 15% of patients who have catheters removed require some sort of additional intervention to remove the catheter.↗
▶Ep 2 · 0:32
epidemiologicalThe actual number of catheters or catheter fragments that get left behind is 0.2 to 2%.↗
▶Ep 2 · 0:32
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 2 · 0:32
quotein a couple case the looking retrospectively at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 2 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 2 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infused through the lines.↗
▶Ep 2 · 1:12
clinicalThere is an association between polyurethane catheter material and catheter retention when compared with silicone catheters.↗
▶Ep 2 · 1:12
clinicalRisk factors for catheter retention include catheters that are indwelling for longer than about a year and a half.↗
▶Ep 2 · 1:31
opinionFor long-term chemotherapy, a silastic line should be considered instead of a polyurethane line.↗
▶Ep 2 · 1:42
quoteWe should be considering maybe a silastic line instead of a polyurethane line.↗
▶Ep 2 · 2:04
quoteIf you surgically, if you're gonna go in for an immunotomy, tug at the catheter, you run into a risk of bleeding.↗
▶Ep 2 · 2:04
clinicalIf you surgically go in for a venotomy and tug at the catheter, you run a risk of bleeding.↗
▶Ep 2 · 2:04
clinicalIn interventional radiology retrieval, there is a risk of the line completely breaking and embolizing distally or of thrombosis occurring during the procedure.↗
Management of Retained Central Venous Catheters
▶Ep 3 · 0:32
epidemiological5 to 15% of patients who have catheters removed require some sort of additional intervention to remove the catheter.↗
▶Ep 3 · 0:32
quotein a couple case series looking retrospectively uh at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 3 · 0:57
epidemiologicalThe actual number of catheters or catheter fragments that get left behind is 0.2 to 2%.↗
▶Ep 3 · 0:57
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 3 · 1:12
clinicalRisk factors for catheter retention include catheters that are indwelling for longer than about a year and a half.↗
▶Ep 3 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 3 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infusion through the line.↗
▶Ep 3 · 1:25
clinicalThere is an association between polyurethane catheter material and catheter retention when compared with silicone catheters.↗
▶Ep 3 · 1:46
guidelineThe recommendation would be to go with silastic catheters for long-term chemotherapy cases.↗
▶Ep 3 · 2:10
clinicalSurgical venotomy to retrieve a retained catheter carries a risk of bleeding.↗
▶Ep 3 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of thrombosis occurring during the procedure.↗
▶Ep 3 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of the line completely breaking and embolizing distally.↗
▶Ep 3 · 2:31
epidemiologicalMultiple studies of patients with retained catheter fragments, with follow-up periods from months to the order of 5 years, found no complications.↗
▶Ep 3 · 2:31
quotewhenever multiple studies which have looked at patients who actually had retained catheter fragments in follow-up periods from months to the order of 5 years, there weren't any complications. So, no thrombosis associated with the line. Fragments and no infections.↗
▶Ep 3 · 2:42
epidemiologicalNo infections were associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
▶Ep 3 · 2:42
epidemiologicalNo thrombosis was associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
Esophagogastric Dissociation for GERD in Severe Neurodisability
▶Ep 4 · 1:01
quotePrimary outcome was operative failure, which they defined as either recurrence of their preoperative reflux symptoms or a requirement of an additional uh anti-reflux surgery.↗
▶Ep 4 · 1:01
host_summaryIn the study, operative failure was defined as either recurrence of preoperative reflux symptoms or requirement of additional anti-reflux surgery.↗
▶Ep 4 · 1:13
host_summaryThe esophagogastric dissociation group had a 4% operative failure rate.↗
▶Ep 4 · 1:13
quotethere was a 4% failure rate in the esophagogastric dissociation group, there was a 21% failure rate in the Nissen group. However, that wasn't statistically significant.↗
▶Ep 4 · 1:13
host_summaryThe Nissen fundoplication group had a 21% operative failure rate.↗
▶Ep 4 · 1:21
host_summaryThe difference in operative failure rates between esophagogastric dissociation and Nissen fundoplication was not statistically significant.↗
▶Ep 4 · 1:23
host_summary17% of patients in the esophagogastric dissociation group continued to require anti-reflux medications after surgery.↗
▶Ep 4 · 1:23
host_summary54% of patients in the Nissen fundoplication group continued to require anti-reflux medications after surgery.↗
▶Ep 4 · 1:23
host_summaryThe difference in continued requirement for anti-reflux medications between groups was statistically significant.↗
▶Ep 4 · 1:29
quote17% of the patients in the esophagogastric dissociation group continued to require them, whereas 54% required it in the Nissan group, um, and that was statistically significant.↗
▶Ep 4 · 1:39
host_summaryCaregiver-evaluated quality of life and symptom scores were the same between the esophagogastric dissociation and Nissen groups.↗
▶Ep 4 · 2:03
host_summaryThe lack of statistical significance in operative failure rates could represent a type 2 error where the sample size was too small to detect an actual difference.↗
▶Ep 4 · 2:03
quotethis could potentially be a type 2 error where there was actually a difference between the two groups and the sample size was just a little bit too small to detect that.↗
▶Ep 4 · 2:26
host_summaryThe study examined perioperative factors including OR time, length of hospital stay, need for ICU stay, and time to full feeds, finding statistically significant differences following expected trends.↗
▶Ep 4 · 2:39
host_summaryThe study did not report on leaks, strictures, or long-term requirement for additional surgeries other than anti-reflux operations.↗
Esophagogastric Dissociation for GERD in Severe Neurodisability
▶Ep 6 · 0:48
host_summaryThe study compared patients with severe GERD and neurologic disability, half undergoing esophagogastric dissociation and half undergoing laparoscopic Nissen.↗
▶Ep 6 · 1:01
quotePrimary outcome was operative failure, which they defined as either recurrence of their preoperative reflux symptoms or a requirement of an additional uh anti-reflux surgery.↗
▶Ep 6 · 1:01
host_summaryPrimary outcome was operative failure, defined as either recurrence of preoperative reflux symptoms or requirement of additional anti-reflux surgery.↗
▶Ep 6 · 1:13
host_summaryThere was a 4% failure rate in the esophagogastric dissociation group and a 21% failure rate in the Nissen group.↗
▶Ep 6 · 1:21
host_summaryThe difference in failure rates between esophagogastric dissociation (4%) and Nissen (21%) was not statistically significant.↗
▶Ep 6 · 1:23
host_summary17% of patients in the esophagogastric dissociation group continued to require anti-reflux medications after surgery, compared to 54% in the Nissen group.↗
▶Ep 6 · 1:29
host_summaryThe difference in continued requirement for anti-reflux medications (17% vs 54%) was statistically significant.↗
▶Ep 6 · 1:39
host_summaryCaregiver-evaluated quality of life and symptom scores were the same between the two groups with no statistically significant difference.↗
▶Ep 6 · 1:46
quoteSo there's no statistically significant difference there.↗
▶Ep 6 · 2:03
quoteAnd the authors brought up that this could potentially be a type 2 error where there was actually a difference between the two groups and the sample size was just a little bit too small to detect that.↗
▶Ep 6 · 2:03
host_summaryThe lack of statistical significance in failure rates could potentially be a type 2 error where there was actually a difference but the sample size was too small to detect it.↗
▶Ep 6 · 2:24
clinicalEsophagogastric dissociation is a much bigger surgery than Nissen fundoplication.↗
▶Ep 6 · 2:24
quoteYeah, it's definitely a much bigger surgery.↗
▶Ep 6 · 2:26
host_summaryThe study examined perioperative factors including time in the OR, length of hospital stay, need for ICU stay, and time to full feeds, with statistically significant differences following expected trends.↗
▶Ep 6 · 2:39
host_summaryThe study did not report on leaks, strictures, or long-term requirement for additional surgeries other than anti-reflux operations.↗
quoteThis paper is about patients who have tracheomalacia and specifically it's called Posterior tracheopexy for severe tracheomalacia.↗
▶Ep 1 · 0:16
host_summaryThe paper by first author Hester Sche and last author Russell Jennings examined 98 patients who had severe tracheomalacia with posterior membranous intrusion.↗
▶Ep 1 · 0:35
host_summaryAll patients received bronchoscopy showing the trachea tended to collapse inward from the posterior aspect.↗
▶Ep 1 · 0:44
host_summaryThe authors distinguished between anterior compression (from the aortic arch) and posterior compression (collapse).↗
▶Ep 1 · 0:54
host_summaryPosterior tracheopexy involves taking pledgeted sutures and sewing the posterior wall of the trachea to the anterior longitudinal ligament of the spine.↗
▶Ep 1 · 1:05
host_summary88% of the 98 patients had esophageal atresia with or without TEF.↗
▶Ep 1 · 1:05
host_summaryPatients were followed anywhere from 1 week to 36 months.↗
▶Ep 1 · 1:15
host_summaryClinical symptoms including cough, barking cough, noisy breathing, and infections improved across the board.↗
▶Ep 1 · 1:25
host_summaryPatients improved on bronchoscopic evaluation.↗
▶Ep 1 · 1:30
host_summaryExercise tolerance did not improve statistically but showed a trend towards improvement.↗
▶Ep 1 · 1:35
host_summaryTracheomalacia is not a homogeneous disease.↗
▶Ep 1 · 1:35
quoteI think the important thing this paper showed us was that tracheomalacia isn't just one homogeneous disease.↗
▶Ep 1 · 1:41
host_summaryThe paper emphasized the importance of systematic bronchoscopic evaluation.↗
▶Ep 1 · 1:45
host_summarySome patients benefit from posterior tracheopexy, some from aortopexy or anterior approach, and some need both.↗
▶Ep 1 · 1:54
host_summaryApproximately 20% of patients in the study required both posterior tracheopexy and aortopexy.↗
▶Ep 1 · 1:58
opinionThere is a need for standardization in the approach to tracheomalacia.↗
Posterior Tracheopexy For Severe Tracheomalacia
▶Ep 2 · 0:16
quoteThis paper is about patients who have tracheomalacia and specifically it's called Posterior tracheopexy for severe tracheomalacia.↗
▶Ep 2 · 0:24
quoteThe first author is Hester She and the last author is Russell Jennings.↗
▶Ep 2 · 0:28
host_summaryThe paper examined 98 patients who had severe tracheomalacia with posterior membranous intrusion.↗
▶Ep 2 · 0:35
host_summaryAll patients received bronchoscopy showing the trachea tended to collapse inward from the posterior aspect.↗
▶Ep 2 · 0:44
host_summaryThe study distinguished between anterior compression (from the aortic arch) and posterior compression (collapse).↗
▶Ep 2 · 0:54
host_summaryPosterior tracheopexy involves taking pledgeted sutures and sewing the posterior wall of the trachea to the anterior longitudinal ligament of the spine.↗
▶Ep 2 · 1:05
host_summaryPatients were followed anywhere from 1 week to 36 months.↗
▶Ep 2 · 1:05
host_summary88% of the 98 patients had esophageal atresia with or without TEF.↗
▶Ep 2 · 1:15
host_summaryClinical symptoms improved pretty much across the board, including cough, barking cough, noisy breathing, and infections.↗
▶Ep 2 · 1:25
host_summaryPatients improved on bronchoscopic evaluation.↗
▶Ep 2 · 1:30
host_summaryExercise tolerance did not improve statistically but showed a trend towards improvement.↗
▶Ep 2 · 1:35
quoteI think the important thing this paper showed us was that tracheomalacia isn't just one homogeneous disease.↗
▶Ep 2 · 1:35
host_summaryTracheomalacia is not one homogeneous disease.↗
▶Ep 2 · 1:41
host_summaryThe paper emphasized the importance of systematic bronchoscopic evaluation.↗
▶Ep 2 · 1:45
host_summarySome patients benefit from posterior tracheopexy, some from aortopexy or anterior approach, and some need both.↗
▶Ep 2 · 1:54
host_summaryAlmost 20% of patients in the study required both posterior tracheopexy and aortopexy.↗
▶Ep 2 · 1:58
opinionThere is a need for standardization in the treatment of tracheomalacia.↗
Esophagogastric Dissociation for GERD in Severe Neurodisability
▶Ep 3 · 1:01
clinicalIn the study, operative failure was defined as either recurrence of preoperative reflux symptoms or requirement of additional anti-reflux surgery.↗
▶Ep 3 · 1:01
quotePrimary outcome was operative failure, which they defined as either recurrence of their preoperative reflux symptoms or a requirement of an additional uh anti-reflux surgery.↗
▶Ep 3 · 1:01
host_summaryIn the study, operative failure was defined as either recurrence of preoperative reflux symptoms or requirement of additional anti-reflux surgery.↗
▶Ep 3 · 1:01
quotePrimary outcome was operative failure, which they defined as either recurrence of their preoperative reflux symptoms or a requirement of an additional uh anti-reflux surgery.↗
▶Ep 3 · 1:13
clinicalThe esophagogastric dissociation group had a 4% operative failure rate.↗
▶Ep 3 · 1:13
host_summaryThe Nissen fundoplication group had a 21% operative failure rate.↗
▶Ep 3 · 1:13
quotethere was a 4% failure rate in the esophagogastric dissociation group, there was a 21% failure rate in the Nissen group. However, that wasn't statistically significant.↗
▶Ep 3 · 1:13
host_summaryThe esophagogastric dissociation group had a 4% operative failure rate.↗
▶Ep 3 · 1:13
clinicalThe Nissen fundoplication group had a 21% operative failure rate.↗
▶Ep 3 · 1:13
quotethere was a 4% failure rate in the esophagogastric dissociation group, there was a 21% failure rate in the Nissen group. However, that wasn't statistically significant.↗
▶Ep 3 · 1:21
clinicalThe difference in operative failure rates between esophagogastric dissociation and Nissen fundoplication was not statistically significant.↗
▶Ep 3 · 1:21
host_summaryThe difference in operative failure rates between esophagogastric dissociation and Nissen fundoplication was not statistically significant.↗
▶Ep 3 · 1:23
host_summary54% of patients in the Nissen fundoplication group continued to require anti-reflux medications after surgery.↗
▶Ep 3 · 1:23
clinical54% of patients in the Nissen fundoplication group continued to require anti-reflux medications after surgery.↗
▶Ep 3 · 1:23
clinicalThe difference in continued requirement for anti-reflux medications between groups was statistically significant.↗
▶Ep 3 · 1:23
host_summaryThe difference in continued requirement for anti-reflux medications between groups was statistically significant.↗
▶Ep 3 · 1:23
host_summary17% of patients in the esophagogastric dissociation group continued to require anti-reflux medications after surgery.↗
▶Ep 3 · 1:23
clinical17% of patients in the esophagogastric dissociation group continued to require anti-reflux medications after surgery.↗
▶Ep 3 · 1:29
quote17% of the patients in the esophagogastric dissociation group continued to require them, whereas 54% required it in the Nissan group, um, and that was statistically significant.↗
▶Ep 3 · 1:29
quote17% of the patients in the esophagogastric dissociation group continued to require them, whereas 54% required it in the Nissan group, um, and that was statistically significant.↗
▶Ep 3 · 1:39
clinicalCaregiver-evaluated quality of life and symptom scores were the same between the esophagogastric dissociation and Nissen groups.↗
▶Ep 3 · 1:39
host_summaryCaregiver-evaluated quality of life and symptom scores were the same between the esophagogastric dissociation and Nissen groups.↗
▶Ep 3 · 2:03
quotethis could potentially be a type 2 error where there was actually a difference between the two groups and the sample size was just a little bit too small to detect that.↗
▶Ep 3 · 2:03
opinionThe lack of statistical significance in operative failure rates could represent a type 2 error where the sample size was too small to detect an actual difference.↗
▶Ep 3 · 2:03
quotethis could potentially be a type 2 error where there was actually a difference between the two groups and the sample size was just a little bit too small to detect that.↗
▶Ep 3 · 2:03
host_summaryThe lack of statistical significance in operative failure rates could represent a type 2 error where the sample size was too small to detect an actual difference.↗
▶Ep 3 · 2:26
host_summaryThe study examined perioperative factors including OR time, length of hospital stay, need for ICU stay, and time to full feeds, finding statistically significant differences following expected trends.↗
▶Ep 3 · 2:26
clinicalThe study examined perioperative factors including OR time, length of hospital stay, need for ICU stay, and time to full feeds, finding statistically significant differences following expected trends.↗
▶Ep 3 · 2:39
clinicalThe study did not report on leaks, strictures, or long-term requirement for additional surgeries other than anti-reflux operations.↗
▶Ep 3 · 2:39
host_summaryThe study did not report on leaks, strictures, or long-term requirement for additional surgeries other than anti-reflux operations.↗
host_summaryThe Karydakis flap is superior to excision alone for pilonidal disease and comparable to the modified Limberg flap; the modified elliptical rotation flap has comparable short-term results.↗
Esophagogastric Dissociation for GERD in Severe Neurodisability
▶Ep 23 · 0:48
clinicalThe study compared patients with severe GERD and neurologic disability, half undergoing esophagogastric dissociation and half undergoing laparoscopic Nissen.↗
▶Ep 23 · 1:01
clinicalPrimary outcome was operative failure, defined as either recurrence of preoperative reflux symptoms or requirement of additional anti-reflux surgery.↗
▶Ep 23 · 1:01
quotePrimary outcome was operative failure, which they defined as either recurrence of their preoperative reflux symptoms or a requirement of an additional uh anti-reflux surgery.↗
▶Ep 23 · 1:13
clinicalThere was a 4% failure rate in the esophagogastric dissociation group and a 21% failure rate in the Nissen group.↗
▶Ep 23 · 1:21
clinicalThe difference in failure rates between esophagogastric dissociation (4%) and Nissen (21%) was not statistically significant.↗
▶Ep 23 · 1:23
clinical17% of patients in the esophagogastric dissociation group continued to require anti-reflux medications after surgery, compared to 54% in the Nissen group.↗
▶Ep 23 · 1:29
clinicalThe difference in continued requirement for anti-reflux medications (17% vs 54%) was statistically significant.↗
▶Ep 23 · 1:39
clinicalCaregiver-evaluated quality of life and symptom scores were the same between the two groups with no statistically significant difference.↗
▶Ep 23 · 1:46
quoteSo there's no statistically significant difference there.↗
▶Ep 23 · 2:03
opinionThe lack of statistical significance in failure rates could potentially be a type 2 error where there was actually a difference but the sample size was too small to detect it.↗
▶Ep 23 · 2:03
quoteAnd the authors brought up that this could potentially be a type 2 error where there was actually a difference between the two groups and the sample size was just a little bit too small to detect that.↗
▶Ep 23 · 2:24
clinicalEsophagogastric dissociation is a much bigger surgery than Nissen fundoplication.↗
▶Ep 23 · 2:24
quoteYeah, it's definitely a much bigger surgery.↗
▶Ep 23 · 2:26
clinicalThe study examined perioperative factors including time in the OR, length of hospital stay, need for ICU stay, and time to full feeds, with statistically significant differences following expected trends.↗
▶Ep 23 · 2:39
clinicalThe study did not report on leaks, strictures, or long-term requirement for additional surgeries other than anti-reflux operations.↗
Management of Retained Central Venous Catheters
▶Ep 25 · 0:32
epidemiological5 to 15% of patients who have catheters removed require some sort of additional intervention to remove the catheter.↗
▶Ep 25 · 0:32
epidemiological5 to 15% of patients who have catheters removed require some sort of additional intervention to remove the catheter.↗
▶Ep 25 · 0:32
quotein a couple case series looking retrospectively uh at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 25 · 0:32
quotein a couple case series looking retrospectively uh at patients who had catheters removed, anywhere from 5 to 15% of patients are going to require some sort of. Additional intervention to remove the catheter.↗
▶Ep 25 · 0:57
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 25 · 0:57
quoteThe actual number of catheters or catheter fragments that get left behind is gonna be from 0.2 to 2%.↗
▶Ep 25 · 0:57
epidemiologicalThe actual number of catheters or catheter fragments that get left behind is 0.2 to 2%.↗
▶Ep 25 · 0:57
epidemiologicalThe actual number of catheters or catheter fragments that get left behind is 0.2 to 2%.↗
▶Ep 25 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 25 · 1:12
quotethe risk factors for catheter retention seem to be patients who have chemotherapy infused through their lines, patients who have catheters that are indwelling for longer than about a year and a half. And then there seems to be an association with polyurethane catheter material when compared with silicone catheters.↗
▶Ep 25 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infusion through the line.↗
▶Ep 25 · 1:12
clinicalRisk factors for catheter retention include catheters that are indwelling for longer than about a year and a half.↗
▶Ep 25 · 1:12
clinicalRisk factors for catheter retention include chemotherapy infusion through the line.↗
▶Ep 25 · 1:12
clinicalRisk factors for catheter retention include catheters that are indwelling for longer than about a year and a half.↗
▶Ep 25 · 1:25
clinicalThere is an association between polyurethane catheter material and catheter retention when compared with silicone catheters.↗
▶Ep 25 · 1:25
clinicalThere is an association between polyurethane catheter material and catheter retention when compared with silicone catheters.↗
▶Ep 25 · 1:46
guidelineThe recommendation would be to go with silastic catheters for long-term chemotherapy cases.↗
▶Ep 25 · 1:46
guidelineThe recommendation would be to go with silastic catheters for long-term chemotherapy cases.↗
▶Ep 25 · 2:10
clinicalSurgical venotomy to retrieve a retained catheter carries a risk of bleeding.↗
▶Ep 25 · 2:10
clinicalSurgical venotomy to retrieve a retained catheter carries a risk of bleeding.↗
▶Ep 25 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of thrombosis occurring during the procedure.↗
▶Ep 25 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of the line completely breaking and embolizing distally.↗
▶Ep 25 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of the line completely breaking and embolizing distally.↗
▶Ep 25 · 2:16
clinicalIn interventional radiology case series attempting endovascular catheter removal, there was a risk of thrombosis occurring during the procedure.↗
▶Ep 25 · 2:31
epidemiologicalMultiple studies of patients with retained catheter fragments, with follow-up periods from months to the order of 5 years, found no complications.↗
▶Ep 25 · 2:31
quotewhenever multiple studies which have looked at patients who actually had retained catheter fragments in follow-up periods from months to the order of 5 years, there weren't any complications. So, no thrombosis associated with the line. Fragments and no infections.↗
▶Ep 25 · 2:31
epidemiologicalMultiple studies of patients with retained catheter fragments, with follow-up periods from months to the order of 5 years, found no complications.↗
▶Ep 25 · 2:31
quotewhenever multiple studies which have looked at patients who actually had retained catheter fragments in follow-up periods from months to the order of 5 years, there weren't any complications. So, no thrombosis associated with the line. Fragments and no infections.↗
▶Ep 25 · 2:42
epidemiologicalNo thrombosis was associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
▶Ep 25 · 2:42
epidemiologicalNo infections were associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
▶Ep 25 · 2:42
epidemiologicalNo infections were associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
▶Ep 25 · 2:42
epidemiologicalNo thrombosis was associated with retained catheter fragments in studies with follow-up from months to 5 years.↗
Do we need Bowel Prep
▶Ep 26 · 0:35
clinicalAdult prospective randomized trials show mechanical bowel prep alone does no good or probably harms patients↗
▶Ep 26 · 0:35
quoteMechanical bowel prep alone in adults is doing them no good or probably harming them, and oral antibiotics that aren't absorbed are probably a good idea.↗
▶Ep 26 · 0:41
clinicalOral antibiotics that are not absorbed are probably beneficial in adult colorectal surgery↗
▶Ep 26 · 0:51
clinicalOne pediatric study showed mechanical bowel prep by itself led to longer hospital stays in children↗
▶Ep 26 · 0:51
clinicalIn one pediatric study, addition of antibiotics to mechanical bowel prep did not make any difference in outcomes↗
▶Ep 26 · 0:51
quoteOne study showed that mechanical bowel prep by itself led to a higher rate of infection and longer hospital stays in kids, and addition of antibiotics didn't make any difference.↗
▶Ep 26 · 0:51
clinicalOne pediatric study showed mechanical bowel prep by itself led to higher infection rates in children↗
▶Ep 26 · 1:01
clinicalAnother pediatric study showed mechanical bowel prep with oral antibiotics made no difference compared to no prep↗
▶Ep 26 · 1:07
opinionFor pediatric colostomy takedown, it is reasonable to omit both mechanical bowel prep and oral antibiotics↗
▶Ep 26 · 1:07
quoteI think for your patient, it probably makes sense to not do either one.↗
quoteThis paper is about patients who have tracheomalacia and specifically it's called Posterior tracheopexy for severe tracheomalacia.↗
▶Ep 1 · 0:16
host_summaryThe paper by first author Hester Sche and last author Russell Jennings examined 98 patients who had severe tracheomalacia with posterior membranous intrusion.↗
▶Ep 1 · 0:35
host_summaryAll patients received bronchoscopy showing the trachea tended to collapse inward from the posterior aspect.↗
▶Ep 1 · 0:44
host_summaryThe authors distinguished between anterior compression (from the aortic arch) and posterior compression (collapse).↗
▶Ep 1 · 0:54
host_summaryPosterior tracheopexy involves taking pledgeted sutures and sewing the posterior wall of the trachea to the anterior longitudinal ligament of the spine.↗
▶Ep 1 · 1:05
host_summary88% of the 98 patients had esophageal atresia with or without TEF.↗
▶Ep 1 · 1:05
host_summaryPatients were followed anywhere from 1 week to 36 months.↗
▶Ep 1 · 1:15
host_summaryClinical symptoms including cough, barking cough, noisy breathing, and infections improved across the board.↗
▶Ep 1 · 1:25
host_summaryPatients improved on bronchoscopic evaluation.↗
▶Ep 1 · 1:30
host_summaryExercise tolerance did not improve statistically but showed a trend towards improvement.↗
▶Ep 1 · 1:35
quoteI think the important thing this paper showed us was that tracheomalacia isn't just one homogeneous disease.↗
▶Ep 1 · 1:35
host_summaryTracheomalacia is not a homogeneous disease.↗
▶Ep 1 · 1:41
host_summaryThe paper emphasized the importance of systematic bronchoscopic evaluation.↗
▶Ep 1 · 1:45
host_summarySome patients benefit from posterior tracheopexy, some from aortopexy or anterior approach, and some need both.↗
▶Ep 1 · 1:54
host_summaryApproximately 20% of patients in the study required both posterior tracheopexy and aortopexy.↗
▶Ep 1 · 1:58
opinionThere is a need for standardization in the approach to tracheomalacia.↗
Posterior Tracheopexy For Severe Tracheomalacia
▶Ep 2 · 0:16
quoteThis paper is about patients who have tracheomalacia and specifically it's called Posterior tracheopexy for severe tracheomalacia.↗
▶Ep 2 · 0:24
quoteThe first author is Hester She and the last author is Russell Jennings.↗
▶Ep 2 · 0:28
host_summaryThe paper examined 98 patients who had severe tracheomalacia with posterior membranous intrusion.↗
▶Ep 2 · 0:35
host_summaryAll patients received bronchoscopy showing the trachea tended to collapse inward from the posterior aspect.↗
▶Ep 2 · 0:44
host_summaryThe study distinguished between anterior compression (from the aortic arch) and posterior compression (collapse).↗
▶Ep 2 · 0:54
host_summaryPosterior tracheopexy involves taking pledgeted sutures and sewing the posterior wall of the trachea to the anterior longitudinal ligament of the spine.↗
▶Ep 2 · 1:05
host_summary88% of the 98 patients had esophageal atresia with or without TEF.↗
▶Ep 2 · 1:05
host_summaryPatients were followed anywhere from 1 week to 36 months.↗
▶Ep 2 · 1:15
host_summaryClinical symptoms improved pretty much across the board, including cough, barking cough, noisy breathing, and infections.↗
▶Ep 2 · 1:25
host_summaryPatients improved on bronchoscopic evaluation.↗
▶Ep 2 · 1:30
host_summaryExercise tolerance did not improve statistically but showed a trend towards improvement.↗
▶Ep 2 · 1:35
quoteI think the important thing this paper showed us was that tracheomalacia isn't just one homogeneous disease.↗
▶Ep 2 · 1:35
host_summaryTracheomalacia is not one homogeneous disease.↗
▶Ep 2 · 1:41
host_summaryThe paper emphasized the importance of systematic bronchoscopic evaluation.↗
▶Ep 2 · 1:45
host_summarySome patients benefit from posterior tracheopexy, some from aortopexy or anterior approach, and some need both.↗
▶Ep 2 · 1:54
host_summaryAlmost 20% of patients in the study required both posterior tracheopexy and aortopexy.↗
▶Ep 2 · 1:58
opinionThere is a need for standardization in the treatment of tracheomalacia.↗