The number one prognostic factor for patients with pancreatoblastoma is complete surgical excision, whether that is at the initial presentation or following neoadjuvant chemotherapy.
The number one prognostic factor for patients with pancreatoblastoma is complete surgical excision, whether that is at the initial presentation or following neoadjuvant chemotherapy.
please we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.
please we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.
please we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.
please we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.
quotewe're not force feeding the kids. Exactly. We're not pushing feeds in the face of ongoing emesis.↗
▶Ep 1 · 39:07
quoteyou really, you can very much be opening a can of worms if you're starting to stick things into the pancreas.↗
▶Ep 1 · 39:16
opinionSticking needles or drains into the pancreas risks introducing infection into sterile necrosis; intervention should be avoided unless there is true significant clinical deterioration.↗
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 4 · 3:38
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 4 · 3:38
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 4 · 3:38
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 4 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 4 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 4 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 4 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 4 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 4 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 4 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 4 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 4 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 4 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 4 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 4 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 4 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 4 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 4 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
▶Ep 4 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
Acute Pancreatitis
▶Ep 6 · 16:41
quotewe're not force feeding the kids. We're not pushing feeds in the face of ongoing emesis.↗
▶Ep 6 · 38:49
clinicalAspiration of pancreatic necrosis to rule out infection carries risk of introducing infection into a sterile collection; empiric antibiotics may be started if fever is present, but aspiration is rarely performed (Cincinnati has needed one necrosectomy in 10 years).↗
▶Ep 6 · 39:03
quoteyou really, you can very much be opening a can of worms if you're starting to stick things into the pancreas.↗
▶Ep 6 · 39:41
quotein the absence of true significant clinical deterioration, we, we really avoid, avoid sticking needles in the pancreas, sticking drains.↗
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 4 · 3:38
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 4 · 3:38
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 4 · 3:38
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 4 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 4 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 4 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 4 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 4 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 4 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 4 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 4 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 4 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 4 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 4 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 4 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 4 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 4 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 4 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
▶Ep 4 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
Acute Pancreatitis
▶Ep 7 · 16:41
quotewe're not force feeding the kids. We're not pushing feeds in the face of ongoing emesis.↗
▶Ep 7 · 38:49
clinicalAspiration of pancreatic necrosis to rule out infection carries risk of introducing infection into a sterile collection; empiric antibiotics may be started if fever is present, but aspiration is rarely performed (Cincinnati has needed one necrosectomy in 10 years).↗
▶Ep 7 · 39:03
quoteyou really, you can very much be opening a can of worms if you're starting to stick things into the pancreas.↗
▶Ep 7 · 39:41
quotein the absence of true significant clinical deterioration, we, we really avoid, avoid sticking needles in the pancreas, sticking drains.↗
quotewe're not force feeding the kids. Exactly. We're not pushing feeds in the face of ongoing emesis.↗
▶Ep 12 · 39:07
quoteyou really, you can very much be opening a can of worms if you're starting to stick things into the pancreas.↗
▶Ep 12 · 39:16
opinionSticking needles or drains into the pancreas risks introducing infection into sterile necrosis; intervention should be avoided unless there is true significant clinical deterioration.↗
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 1 · 3:38
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 1 · 3:38
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 1 · 3:38
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 1 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 1 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 1 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 1 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 1 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 1 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 1 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 1 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 1 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 1 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 1 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 1 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 1 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 1 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 1 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
▶Ep 1 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
clinicalElevated lipase and elevated bilirubin suggest obstruction in the pancreatic head, which can be caused by neoplasms or more commonly in pediatrics by non-neoplastic findings such as autoimmune pancreatitis or complications of pancreatitis.↗
▶Ep 1 · 1:21
clinicalElevated lipase and elevated bilirubin suggest obstruction in the pancreatic head, which can be caused by neoplasms or more commonly in pediatrics by non-neoplastic findings such as autoimmune pancreatitis or complications of pancreatitis.↗
▶Ep 1 · 5:14
epidemiologicalPancreatoblastoma is the most common malignant pancreatic tumor in children, typically presenting in patients less than 10 years of age.↗
▶Ep 1 · 5:14
epidemiologicalPancreatoblastoma is the most common malignant pancreatic tumor in children, typically presenting in patients less than 10 years of age.↗
▶Ep 1 · 5:40
clinicalIn pancreatoblastoma, alpha-fetoprotein is elevated in up to 80% of cases.↗
▶Ep 1 · 5:40
clinicalIn pancreatoblastoma, alpha-fetoprotein is elevated in up to 80% of cases.↗
▶Ep 1 · 5:50
epidemiologicalUp to 45-50% of pancreatoblastoma cases present with metastases.↗
▶Ep 1 · 5:50
epidemiologicalUp to 45-50% of pancreatoblastoma cases present with metastases.↗
▶Ep 1 · 6:00
clinicalPancreatoblastomas respond well to chemotherapy with a cisplatin and doxorubicin-based regimen.↗
▶Ep 1 · 6:00
clinicalPancreatoblastomas respond well to chemotherapy with a cisplatin and doxorubicin-based regimen.↗
▶Ep 1 · 6:10
quoteThe number one prognostic factor for patients with pancreatoblastoma is complete surgical excision, whether that is at the initial presentation or following neoadjuvant chemotherapy.↗
▶Ep 1 · 6:10
clinicalThe number one prognostic factor for pancreatoblastoma is complete surgical excision, whether at initial presentation or following neoadjuvant chemotherapy.↗
▶Ep 1 · 6:10
quoteThe number one prognostic factor for patients with pancreatoblastoma is complete surgical excision, whether that is at the initial presentation or following neoadjuvant chemotherapy.↗
▶Ep 1 · 6:10
clinicalThe number one prognostic factor for pancreatoblastoma is complete surgical excision, whether at initial presentation or following neoadjuvant chemotherapy.↗
▶Ep 1 · 6:25
epidemiologicalSolid pseudopapillary neoplasms are more common in young female patients, typically in their second or third decade of life.↗
▶Ep 1 · 6:25
epidemiologicalSolid pseudopapillary neoplasms are more common in young female patients, typically in their second or third decade of life.↗
▶Ep 1 · 6:40
clinicalSolid pseudopapillary tumors are indolent and slow-growing, often presenting with very large masses in the body and tail of the pancreas.↗
▶Ep 1 · 6:40
clinicalSolid pseudopapillary tumors are indolent and slow-growing, often presenting with very large masses in the body and tail of the pancreas.↗
▶Ep 1 · 6:50
quoteYou really actually want to avoid enucleation or simply biopsy of these lesions. There tends to be a high recurrence rate if you're simply trying to enucleate these lesions.↗
▶Ep 1 · 6:50
quoteYou really actually want to avoid enucleation or simply biopsy of these lesions. There tends to be a high recurrence rate if you're simply trying to enucleate these lesions.↗
▶Ep 1 · 6:55
clinicalEnucleation or simple biopsy of solid pseudopapillary neoplasms should be avoided due to high recurrence rates; complete surgical resection is required.↗
▶Ep 1 · 6:55
clinicalEnucleation or simple biopsy of solid pseudopapillary neoplasms should be avoided due to high recurrence rates; complete surgical resection is required.↗
▶Ep 1 · 7:04
epidemiologicalSolid pseudopapillary neoplasms have a recurrence rate of up to 10% but excellent long-term survival with 95% 10-year survival.↗
▶Ep 1 · 7:04
epidemiologicalSolid pseudopapillary neoplasms have a recurrence rate of up to 10% but excellent long-term survival with 95% 10-year survival.↗
▶Ep 1 · 9:30
epidemiologicalNeuroendocrine tumors make up about 1-2% of all pancreatic tumors and can be either benign adenomas or malignant carcinomas.↗
▶Ep 1 · 9:30
epidemiologicalNeuroendocrine tumors make up about 1-2% of all pancreatic tumors and can be either benign adenomas or malignant carcinomas.↗
▶Ep 1 · 9:45
epidemiologicalNeuroendocrine tumors tend to present in children over 10 years of age, though they are more common in middle-aged patients.↗
▶Ep 1 · 9:45
epidemiologicalNeuroendocrine tumors tend to present in children over 10 years of age, though they are more common in middle-aged patients.↗
▶Ep 1 · 9:55
clinicalIn 10% of patients, neuroendocrine tumors may present in the setting of multiple endocrine neoplasia type 1, von Hippel-Lindau, or tuberous sclerosis.↗
▶Ep 1 · 9:55
clinicalIn 10% of patients, neuroendocrine tumors may present in the setting of multiple endocrine neoplasia type 1, von Hippel-Lindau, or tuberous sclerosis.↗
▶Ep 1 · 10:10
epidemiologicalInsulinoma is the most common neuroendocrine tumor, accounting for almost 50% of pancreatic neuroendocrine tumors, followed by gastrinomas at 30%.↗
▶Ep 1 · 10:10
epidemiologicalInsulinoma is the most common neuroendocrine tumor, accounting for almost 50% of pancreatic neuroendocrine tumors, followed by gastrinomas at 30%.↗
▶Ep 1 · 10:25
epidemiologicalInsulinomas are typically benign; 6% can be malignant. 90% are solitary, 10% are associated with MEN1.↗
▶Ep 1 · 10:25
epidemiologicalInsulinomas are typically benign; 6% can be malignant. 90% are solitary, 10% are associated with MEN1.↗
▶Ep 1 · 10:40
clinicalInsulinomas present with Whipple's triad: symptoms of hypoglycemia, low fasting blood glucose, and symptom resolution with glucose administration.↗
▶Ep 1 · 10:40
clinicalInsulinomas present with Whipple's triad: symptoms of hypoglycemia, low fasting blood glucose, and symptom resolution with glucose administration.↗
▶Ep 1 · 12:00
clinicalOn imaging, a solid lesion in the pancreas is more worrisome than a cystic lesion when found incidentally.↗
▶Ep 1 · 12:00
clinicalOn imaging, a solid lesion in the pancreas is more worrisome than a cystic lesion when found incidentally.↗
▶Ep 1 · 13:40
clinicalUltrasound is low cost and easily accessible but the pancreas is often suboptimally visualized and characterization of pancreatic masses is poor.↗
▶Ep 1 · 13:40
clinicalUltrasound is low cost and easily accessible but the pancreas is often suboptimally visualized and characterization of pancreatic masses is poor.↗
▶Ep 1 · 14:00
clinicalCT scan is rapidly acquired with good resolution but has downsides of radiation and need for contrast; it is often used for solid tumor staging.↗
▶Ep 1 · 14:00
clinicalCT scan is rapidly acquired with good resolution but has downsides of radiation and need for contrast; it is often used for solid tumor staging.↗
▶Ep 1 · 14:20
clinicalMRI provides better differentiation between solid and cystic or fluid components and can better characterize components of a pancreatic mass.↗
▶Ep 1 · 14:20
clinicalMRI provides better differentiation between solid and cystic or fluid components and can better characterize components of a pancreatic mass.↗
▶Ep 1 · 15:03
quoteWe can really never confidently differentiate a benign versus a malignant lesion of the pancreas simply with cross-sectional imaging, whether it be CT scan or MRI.↗
▶Ep 1 · 15:03
quoteWe can really never confidently differentiate a benign versus a malignant lesion of the pancreas simply with cross-sectional imaging, whether it be CT scan or MRI.↗
▶Ep 1 · 15:03
clinicalCross-sectional imaging (CT or MRI) cannot confidently differentiate a benign versus malignant pancreatic lesion.↗
▶Ep 1 · 15:03
clinicalCross-sectional imaging (CT or MRI) cannot confidently differentiate a benign versus malignant pancreatic lesion.↗
▶Ep 1 · 15:25
clinicalA completely cystic pancreatic lesion is less concerning for malignancy, but if the mass has solid components, it becomes more concerning for neoplasm.↗
▶Ep 1 · 15:25
clinicalA completely cystic pancreatic lesion is less concerning for malignancy, but if the mass has solid components, it becomes more concerning for neoplasm.↗
▶Ep 1 · 17:20
clinicalPediatric EUS is not practical in many institutions because there are not many practitioners in the pediatric GI community comfortable with pediatric EUS.↗
▶Ep 1 · 17:20
clinicalPediatric EUS is not practical in many institutions because there are not many practitioners in the pediatric GI community comfortable with pediatric EUS.↗
▶Ep 1 · 18:24
epidemiologicalIn the pediatric realm, autoimmune pancreatitis is more common than pancreatic neoplasm.↗
▶Ep 1 · 18:24
epidemiologicalIn the pediatric realm, autoimmune pancreatitis is more common than pancreatic neoplasm.↗
▶Ep 1 · 18:35
clinicalWith negative biliary cytology and after biliary and pancreatic duct stenting, a four-week steroid trial with taper can be initiated for presumed autoimmune pancreatitis, even if IgG4 findings are normal.↗
▶Ep 1 · 18:35
clinicalWith negative biliary cytology and after biliary and pancreatic duct stenting, a four-week steroid trial with taper can be initiated for presumed autoimmune pancreatitis, even if IgG4 findings are normal.↗
▶Ep 1 · 19:05
clinicalType 1 autoimmune pancreatitis is IgG4-mediated; type 2 autoimmune pancreatitis is IgG4-negative.↗
▶Ep 1 · 19:05
clinicalType 1 autoimmune pancreatitis is IgG4-mediated; type 2 autoimmune pancreatitis is IgG4-negative.↗
▶Ep 1 · 20:03
clinicalAutoimmune pancreatitis with a pancreatic head mass is typically very steroid responsive, with rapid resolution of the mass in most cases.↗
▶Ep 1 · 20:03
clinicalAutoimmune pancreatitis with a pancreatic head mass is typically very steroid responsive, with rapid resolution of the mass in most cases.↗
▶Ep 1 · 22:40
clinicalFor malignant pancreatic head lesions, a radical resection (Whipple pancreaticoduodenectomy) is required; for benign or borderline benign lesions, duodenum-preserving pancreatic head resections (Beger or Berne procedures) may be considered.↗
▶Ep 1 · 22:40
clinicalFor malignant pancreatic head lesions, a radical resection (Whipple pancreaticoduodenectomy) is required; for benign or borderline benign lesions, duodenum-preserving pancreatic head resections (Beger or Berne procedures) may be considered.↗
▶Ep 1 · 23:00
quoteWe really have to consider degree of resection whenever we're considering removing a portion of the pancreas because we have to think about endocrine and exocrine needs long-term.↗
▶Ep 1 · 23:00
quoteWe really have to consider degree of resection whenever we're considering removing a portion of the pancreas because we have to think about endocrine and exocrine needs long-term.↗
▶Ep 1 · 23:20
epidemiologicalStudies report up to about a 10% risk of diabetes (endocrine impairment) after just a distal pancreatectomy in the setting of otherwise normal pancreas.↗
▶Ep 1 · 23:20
epidemiologicalStudies report up to about a 10% risk of diabetes (endocrine impairment) after just a distal pancreatectomy in the setting of otherwise normal pancreas.↗
▶Ep 1 · 24:50
clinicalEnucleation may be appropriate for pancreatic neuroendocrine tumors but should be used sparingly; it is not recommended for solid pseudopapillary neoplasms due to higher recurrence risk.↗
▶Ep 1 · 24:50
clinicalEnucleation may be appropriate for pancreatic neuroendocrine tumors but should be used sparingly; it is not recommended for solid pseudopapillary neoplasms due to higher recurrence risk.↗
▶Ep 1 · 27:20
quoteThe literature is actually replete with cases of these masquerades and mimicking.↗
▶Ep 1 · 27:20
quoteThe literature is actually replete with cases of these masquerades and mimicking.↗
▶Ep 1 · 28:53
clinicalType 1 autoimmune pancreatitis is IgG4-related systemic disease involving multiple organs (sialoadenitis, sclerosing cholangitis, retroperitoneal fibrosis) and responds quickly to steroids; IgG4 levels are elevated in 90% of patients.↗
▶Ep 1 · 28:53
clinicalType 1 autoimmune pancreatitis is IgG4-related systemic disease involving multiple organs (sialoadenitis, sclerosing cholangitis, retroperitoneal fibrosis) and responds quickly to steroids; IgG4 levels are elevated in 90% of patients.↗
▶Ep 1 · 29:40
clinicalType 2 autoimmune pancreatitis is pancreas-specific with normal IgG4 levels; 30% of patients also have IBD. Histology shows idiopathic duct-centric pancreatitis.↗
▶Ep 1 · 29:40
clinicalType 2 autoimmune pancreatitis is pancreas-specific with normal IgG4 levels; 30% of patients also have IBD. Histology shows idiopathic duct-centric pancreatitis.↗
▶Ep 1 · 30:10
epidemiologicalOver 90% of children with autoimmune pancreatitis present with abdominal pain; about 40% present with obstructive jaundice.↗
▶Ep 1 · 30:10
epidemiologicalOver 90% of children with autoimmune pancreatitis present with abdominal pain; about 40% present with obstructive jaundice.↗
▶Ep 1 · 30:30
epidemiologicalPositive serologies for IgG4 are described in only 22% of children with autoimmune pancreatitis in one study.↗
▶Ep 1 · 30:30
epidemiologicalPositive serologies for IgG4 are described in only 22% of children with autoimmune pancreatitis in one study.↗
▶Ep 1 · 30:45
epidemiologicalIn pediatric autoimmune pancreatitis, focal enlargement in the pancreatic head occurs in about 50% of patients; global pancreatic enlargement in 30%; main pancreatic duct irregularity in two-thirds; common bile duct strictures in 55%; and the capsule-like rim sign in only 16%.↗
▶Ep 1 · 30:45
epidemiologicalIn pediatric autoimmune pancreatitis, focal enlargement in the pancreatic head occurs in about 50% of patients; global pancreatic enlargement in 30%; main pancreatic duct irregularity in two-thirds; common bile duct strictures in 55%; and the capsule-like rim sign in only 16%.↗
▶Ep 1 · 31:30
epidemiological93% of pediatric patients with autoimmune pancreatitis respond to steroids, indicating very steroid-responsive disease.↗
▶Ep 1 · 31:30
epidemiological93% of pediatric patients with autoimmune pancreatitis respond to steroids, indicating very steroid-responsive disease.↗
▶Ep 1 · 32:30
epidemiologicalAutoimmune pancreatitis in children more commonly follows a type 2 presentation rather than type 1 or IgG4-related presentation, based on data from the INSPIRE consortium and European pancreatic consortium.↗
▶Ep 1 · 32:30
epidemiologicalAutoimmune pancreatitis in children more commonly follows a type 2 presentation rather than type 1 or IgG4-related presentation, based on data from the INSPIRE consortium and European pancreatic consortium.↗
▶Ep 1 · 33:20
clinicalIdeally, a tissue diagnosis should be obtained before initiating therapy for autoimmune pancreatitis, but barriers in pediatrics (limited EUS-skilled endoscopists and pathologists, inadequate biopsies) often cannot be overcome.↗
▶Ep 1 · 33:20
clinicalIdeally, a tissue diagnosis should be obtained before initiating therapy for autoimmune pancreatitis, but barriers in pediatrics (limited EUS-skilled endoscopists and pathologists, inadequate biopsies) often cannot be overcome.↗
▶Ep 1 · 33:50
guidelineThe diagnosis of autoimmune pancreatitis in children can be made with a combination of clinical and imaging findings because the risk of pediatric neoplasm is lower than autoimmune pancreatitis.↗
▶Ep 1 · 33:50
guidelineThe diagnosis of autoimmune pancreatitis in children can be made with a combination of clinical and imaging findings because the risk of pediatric neoplasm is lower than autoimmune pancreatitis.↗
▶Ep 1 · 34:30
clinicalClinical response to corticosteroid therapy for autoimmune pancreatitis should be seen within a few weeks; imaging response should be anticipated after about three months.↗
▶Ep 1 · 34:30
clinicalClinical response to corticosteroid therapy for autoimmune pancreatitis should be seen within a few weeks; imaging response should be anticipated after about three months.↗
▶Ep 1 · 34:45
quoteYou don't want to keep treating something that ends up being a pancreatic neoplasm with steroids.↗
▶Ep 1 · 34:45
quoteYou don't want to keep treating something that ends up being a pancreatic neoplasm with steroids.↗
quotewe're not force feeding the kids. Exactly. We're not pushing feeds in the face of ongoing emesis.↗
▶Ep 2 · 39:07
quoteyou really, you can very much be opening a can of worms if you're starting to stick things into the pancreas.↗
▶Ep 2 · 39:16
opinionSticking needles or drains into the pancreas risks introducing infection into sterile necrosis; intervention should be avoided unless there is true significant clinical deterioration.↗
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 8 · 3:38
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 8 · 3:38
quoteAnything you wanted to know about the pancreas, uh, and we'll spend the next 4 hours talking about surgical approaches.↗
▶Ep 8 · 3:38
clinicalThe day's sessions will cover surgical approaches, interventional endoscopic approaches, and medical management of acute, acute recurrent, and chronic pancreatitis↗
▶Ep 8 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 8 · 4:05
clinicalDr. Joe Palermo is a pediatric gastroenterologist and medical lead of the total pancreatectomy and islet auto transplantation program↗
▶Ep 8 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 8 · 4:23
clinicalKen Goldschneider is director of pain management at Cincinnati Children's, professor of clinical pediatrics and anesthesia, and plays a central role in pain management for patients with pancreatic diseases↗
▶Ep 8 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 8 · 4:40
clinicalDr. Maisam Abu El-Haija is a gastroenterologist, co-director of the course, and medical director of the Pancreas Care Center↗
▶Ep 8 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 8 · 4:54
clinicalTom Lynn is a gastroenterologist who manages the vast majority or all endoscopic needs for children with pancreatic disorders, director of endoscopy for the Pancreas Care Center, and co-director of endoscopy for the division of gastroenterology↗
▶Ep 8 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 8 · 5:17
clinicalAndrew Trout is the lead radiologist for the Pancreas Care Center, assistant professor of radiology, and dual certified in pediatric radiology and nuclear medicine↗
▶Ep 8 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 8 · 5:33
clinicalDr. Deb Elder is the endocrine director for the Pancreas Care Center and will join later in the event↗
▶Ep 8 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 8 · 5:47
clinicalDr. Milton Smith is medical director of therapeutic ERCP at University of Cincinnati and will join later in the event↗
▶Ep 8 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
▶Ep 8 · 5:53
quoteplease we'd like to keep this, uh, uh, highly interactive, so, um, bring us your questions, bring us your comments, and, uh, we hope to be able to answer them.↗
Acute Pancreatitis
▶Ep 12 · 16:41
quotewe're not force feeding the kids. We're not pushing feeds in the face of ongoing emesis.↗
▶Ep 12 · 38:49
clinicalAspiration of pancreatic necrosis to rule out infection carries risk of introducing infection into a sterile collection; empiric antibiotics may be started if fever is present, but aspiration is rarely performed (Cincinnati has needed one necrosectomy in 10 years).↗
▶Ep 12 · 39:03
quoteyou really, you can very much be opening a can of worms if you're starting to stick things into the pancreas.↗
▶Ep 12 · 39:41
quotein the absence of true significant clinical deterioration, we, we really avoid, avoid sticking needles in the pancreas, sticking drains.↗
