Sarah Choi

63 statements · 3 topics

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The urine sodium to urine creatinine ratio offers a non-invasive measure, which accounts for variable urine flow and has shown to be strongly correlated with FINA, thus potentially acting as a more accurate marker of sodium status.
quote · Gastroschisis
Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits.
quote · Gastroschisis
Sodium depletion can go unrecognized, resulting in poor growth, refractory to increased caloric intake.
At BC Women's Hospital, urine sodium is used as a non-invasive marker to estimate total body sodium in infants with intestinal failure, with a value above 30 suggesting sodium sufficiency.
clinical · Intestinal Failure
The urine sodium to urine creatinine ratio offers a non-invasive measure which accounts for variable urine flow and has shown to be strongly correlated with fractional excretion of sodium.
clinical · Intestinal Rehab
Fractional excretion of sodium is the optimum measure of total body sodium but is inconvenient in the pediatric population as it requires a paired urine and blood sample.
clinical · Intestinal Rehab

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Sarah's statements about Gastroschisis 21 statements

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CAPS - The use of urine sodium to creatinine ratio as a marker of total body sodium in infants with intestinal failure - Sara Choi

Statement Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits. Open
Quotation Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits. Open
Quotation Sodium depletion can go unrecognized, resulting in poor growth, refractory to increased caloric intake. Open
Statement Sodium depletion can go unrecognized, resulting in poor growth refractory to increased caloric intake. Open
Statement Sodium supplementation has been shown to be associated with weight gain and overall growth in infants with intestinal failure. Open
Statement Serum sodium does not reflect total sodium stores. Open
Quotation It is difficult to determine how much sodium should be supplemented as serum sodium does not reflect total sodium stores. Open
Statement Fractional excretion of sodium is the optimum measure of total body sodium but is inconvenient in the pediatric population as it requires a paired urine and blood sample. Open
Statement At BC Women's Hospital, urine sodium is used as a non-invasive marker to estimate total body sodium in infants with intestinal failure, with a value above 30 suggesting sodium sufficiency. Open
Statement Urine sodium doesn't account for volume status, therefore can result in oversupplementation or under supplementation with sodium. Open
Quotation The urine sodium to urine creatinine ratio offers a non-invasive measure, which accounts for variable urine flow and has shown to be strongly correlated with FINA, thus potentially acting as a more accurate marker of sodium status. Open
Statement The urine sodium to urine creatinine ratio offers a non-invasive measure which accounts for variable urine flow and has shown to be strongly correlated with fractional excretion of sodium. Open
Statement The use of the urine sodium to creatinine ratio has not yet been validated in the intestinal failure population. Open
Statement In the study cohort of 22 infants, median gestational age was 31 weeks, median birth weight was 1.9 kg, and median age of enrollment was 8 days. Open
Statement Gastroschisis was the most common etiology of intestinal failure in the study cohort. Open
Statement There was no significant correlation between either urine sodium or the ratio with daily weight gain when evaluating the entire data set. Open
Statement The ratio was more strongly associated with sodium intake when compared to urine sodium alone. Open
Statement Urine sodium values above 29 and ratio values above 35 best predicted adequate weight gain. Open
Statement The urine sodium threshold of 29 is similar to previous studies, as it is generally accepted that urine sodium values above 30 is suggestive of sodium sufficiency. Open
Statement In the majority of urine sodium and ratio values, both markers were concordant, meaning that if urine sodium value met the threshold, then the ratio also met the threshold. Open
Statement In 19% of the time, the urine sodium and ratio values were discordant. Open
Sarah's statements about Intestinal Failure 21 statements

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CAPS - The use of urine sodium to creatinine ratio as a marker of total body sodium in infants with intestinal failure - Sara Choi

Quotation Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits. Open
Statement Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits. Open
Statement Sodium depletion can go unrecognized, resulting in poor growth refractory to increased caloric intake. Open
Quotation Sodium depletion can go unrecognized, resulting in poor growth, refractory to increased caloric intake. Open
Statement Sodium supplementation has been shown to be associated with weight gain and overall growth in infants with intestinal failure. Open
Quotation It is difficult to determine how much sodium should be supplemented as serum sodium does not reflect total sodium stores. Open
Statement Serum sodium does not reflect total sodium stores. Open
Statement Fractional excretion of sodium is the optimum measure of total body sodium but is inconvenient in the pediatric population as it requires a paired urine and blood sample. Open
Statement At BC Women's Hospital, urine sodium is used as a non-invasive marker to estimate total body sodium in infants with intestinal failure, with a value above 30 suggesting sodium sufficiency. Open
Statement Urine sodium doesn't account for volume status, therefore can result in oversupplementation or under supplementation with sodium. Open
Statement The urine sodium to urine creatinine ratio offers a non-invasive measure which accounts for variable urine flow and has shown to be strongly correlated with fractional excretion of sodium. Open
Quotation The urine sodium to urine creatinine ratio offers a non-invasive measure, which accounts for variable urine flow and has shown to be strongly correlated with FINA, thus potentially acting as a more accurate marker of sodium status. Open
Statement The use of the urine sodium to creatinine ratio has not yet been validated in the intestinal failure population. Open
Statement In the study cohort of 22 infants, median gestational age was 31 weeks, median birth weight was 1.9 kg, and median age of enrollment was 8 days. Open
Statement Gastroschisis was the most common etiology of intestinal failure in the study cohort. Open
Statement There was no significant correlation between either urine sodium or the ratio with daily weight gain when evaluating the entire data set. Open
Statement The ratio was more strongly associated with sodium intake when compared to urine sodium alone. Open
Statement Urine sodium values above 29 and ratio values above 35 best predicted adequate weight gain. Open
Statement The urine sodium threshold of 29 is similar to previous studies, as it is generally accepted that urine sodium values above 30 is suggestive of sodium sufficiency. Open
Statement In the majority of urine sodium and ratio values, both markers were concordant, meaning that if urine sodium value met the threshold, then the ratio also met the threshold. Open
Statement In 19% of the time, the urine sodium and ratio values were discordant. Open
Sarah's statements about Intestinal Rehab 21 statements

Open the Intestinal Rehab collection →

CAPS - The use of urine sodium to creatinine ratio as a marker of total body sodium in infants with intestinal failure - Sara Choi

Quotation Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits. Open
Statement Infants with intestinal failure have compromised intestinal function, putting them at increased risk of malabsorption and electrolyte and fluid deficits. Open
Statement Sodium depletion can go unrecognized, resulting in poor growth refractory to increased caloric intake. Open
Quotation Sodium depletion can go unrecognized, resulting in poor growth, refractory to increased caloric intake. Open
Statement Sodium supplementation has been shown to be associated with weight gain and overall growth in infants with intestinal failure. Open
Statement Serum sodium does not reflect total sodium stores. Open
Quotation It is difficult to determine how much sodium should be supplemented as serum sodium does not reflect total sodium stores. Open
Statement Fractional excretion of sodium is the optimum measure of total body sodium but is inconvenient in the pediatric population as it requires a paired urine and blood sample. Open
Statement At BC Women's Hospital, urine sodium is used as a non-invasive marker to estimate total body sodium in infants with intestinal failure, with a value above 30 suggesting sodium sufficiency. Open
Statement Urine sodium doesn't account for volume status, therefore can result in oversupplementation or under supplementation with sodium. Open
Quotation The urine sodium to urine creatinine ratio offers a non-invasive measure, which accounts for variable urine flow and has shown to be strongly correlated with FINA, thus potentially acting as a more accurate marker of sodium status. Open
Statement The urine sodium to urine creatinine ratio offers a non-invasive measure which accounts for variable urine flow and has shown to be strongly correlated with fractional excretion of sodium. Open
Statement The use of the urine sodium to creatinine ratio has not yet been validated in the intestinal failure population. Open
Statement In the study cohort of 22 infants, median gestational age was 31 weeks, median birth weight was 1.9 kg, and median age of enrollment was 8 days. Open
Statement Gastroschisis was the most common etiology of intestinal failure in the study cohort. Open
Statement There was no significant correlation between either urine sodium or the ratio with daily weight gain when evaluating the entire data set. Open
Statement The ratio was more strongly associated with sodium intake when compared to urine sodium alone. Open
Statement Urine sodium values above 29 and ratio values above 35 best predicted adequate weight gain. Open
Statement The urine sodium threshold of 29 is similar to previous studies, as it is generally accepted that urine sodium values above 30 is suggestive of sodium sufficiency. Open
Statement In the majority of urine sodium and ratio values, both markers were concordant, meaning that if urine sodium value met the threshold, then the ratio also met the threshold. Open
Statement In 19% of the time, the urine sodium and ratio values were discordant. Open