If any physician has a patient with intestinal failure, we can consult at any point and provide support. But definitely, patients that are not making progress, that are on prolonged TPN have significant comorbidities, you wanna make sure you refer them sooner than later.
If any physician has a patient with intestinal failure, we can consult at any point and provide support. But definitely, patients that are not making progress, that are on prolonged TPN have significant comorbidities, you wanna make sure you refer them sooner than later.
If any physician has a patient with intestinal failure, we can consult at any point and provide support. But definitely, patients that are not making progress, that are on prolonged TPN have significant comorbidities, you wanna make sure you refer them sooner than later.
We don't have a clear-cut guideline because every patient is extremely unique, born in a different gestational age, had a different bowel resection, has a different anatomy, different set of comorbidities.
Advancements in Pediatric Intestinal Failure: Innovative Therapies and Improved Outcomes
▶Ep 28 · 0:26
clinicalIntestinal failure is defined as the reduction of functioning intestinal mass below that which can sustain life, resulting in dependence on supplemental parenteral support for a minimum of 60 days within a 74 consecutive day interval.↗
▶Ep 28 · 0:26
quoteThe reduction of functioning intestinal mass below that which can sustain life, resulting in dependence of supplemental parental support for a minimum of 60 days within a 74 consecutive day interval.↗
▶Ep 28 · 0:43
quoteMore than 50% of the cases that we see are related to short bowel syndrome, some mucosal enteropathies and some dysmotility disorders.↗
▶Ep 28 · 0:43
epidemiologicalMore than 50% of intestinal failure cases are related to short bowel syndrome, with additional cases from mucosal enteropathies and dysmotility disorders.↗
▶Ep 28 · 0:55
clinicalMost causes of short bowel syndrome in pediatrics occur during the neonatal period, including gastroschisis, necrotizing enterocolitis, bowel atresia, and intestinal volvulus.↗
▶Ep 28 · 1:18
quoteThe field is starting to focus on neurocognitive outcomes, quality of life, and caregiver burnout.↗
▶Ep 28 · 1:18
opinionThe field is now focusing on neurocognitive outcomes, quality of life, and caregiver burnout as more children survive intestinal failure.↗
▶Ep 28 · 1:37
clinicalThe cause of chronic intestinal inflammation in intestinal failure survivors is not known.↗
clinicalIntestinal rehabilitation treatment strategy lacks clear-cut guidelines because every patient is unique with different gestational age, bowel resection, anatomy, and comorbidities.↗
▶Ep 28 · 1:52
quoteWe don't have a clear-cut guideline because every patient is extremely unique, born in a different gestational age, had a different bowel resection, has a different anatomy, different set of comorbidities.↗
▶Ep 28 · 2:07
clinicalThe goal of intestinal rehabilitation is to optimize intestinal function and adaptation before the development of irreversible complications.↗
▶Ep 28 · 2:07
quoteThe goal is to optimize intestinal function and adaptation before the development of irreversible complications.↗
▶Ep 28 · 2:30
clinicalIntestinal adaptation is an active compensatory process that starts immediately after bowel resection.↗
▶Ep 28 · 2:30
quoteIntestinal adaptation is an active process, is a compensatory process that starts happening right after bowel resection.↗
▶Ep 28 · 2:42
clinicalFood, bacteria, and hormones in the gut are important factors that enhance intestinal adaptation.↗
▶Ep 28 · 2:42
quoteFood, bacteria and hormones in the gut is important.↗
▶Ep 28 · 2:45
quoteWe are trying to regain function of the bowel, so eventually the person doesn't need TPN anymore.↗
▶Ep 28 · 3:11
quoteInternal autonomy is getting off TPN, having all your nutrition going to your gut, either by mouth or by a feeding tube.↗
▶Ep 28 · 3:11
clinicalEnteral autonomy is defined as getting off TPN with all nutrition going to the gut, either by mouth or by feeding tube.↗
▶Ep 28 · 3:33
quoteFrom 2010 to 2015, that study was repeated with double the number of patients and still about 50% reached enter autonomy. But the number of transplants significantly decreased as well as death.↗
▶Ep 28 · 3:33
epidemiologicalFrom 2010 to 2015, a repeat study with double the number of patients showed approximately 50% still reached enteral autonomy, but the number of transplants and deaths significantly decreased.↗
▶Ep 28 · 3:46
clinicalThe establishment of multidisciplinary teams is one factor that changed outcomes in intestinal failure.↗
▶Ep 28 · 3:46
quoteOne of the things that changed the outcome is the establishment of multidisciplinary teams.↗
▶Ep 28 · 4:03
quoteThe residue is more about length, the more about, the better. Follow up on an institution that has an IR program and no-step procedure.↗
▶Ep 28 · 4:03
clinicalPredictors of reaching enteral autonomy include residual bowel length (more is better), follow-up at an institution with an intestinal rehabilitation program, and no STEP procedure.↗
▶Ep 28 · 4:19
guidelinePatients should be referred to intestinal rehabilitation programs when not making progress, on prolonged TPN, or have significant comorbidities, preferably sooner rather than later.↗
▶Ep 28 · 4:19
quoteIf any physician has a patient with intestinal failure, we can consult at any point and provide support. But definitely, patients that are not making progress, that are on prolonged TPN have significant comorbidities, you wanna make sure you refer them sooner than later.↗
▶Ep 28 · 4:39
quoteYou don't want to refer them when several complications already happened and now there's not a lot we can do other than transplant.↗
▶Ep 28 · 4:39
guidelinePatients should not be referred to intestinal rehabilitation when several irreversible complications have already occurred and transplant is the only remaining option.↗
▶Ep 28 · 4:49
clinicalIntestinal transplantation is considered when there are irreversible complications, though the number of transplants has significantly decreased over the last several decades.↗
▶Ep 28 · 4:49
quoteWe transplant when we have irreversible complications, or we have so many things to do to avoid that. The number of transplants has significantly decreased over the last several decades.↗
Advancements in Pediatric Intestinal Failure: Innovative Therapies and Improved Outcomes
▶Ep 108 · 0:26
clinicalIntestinal failure is defined as the reduction of functioning intestinal mass below that which can sustain life, resulting in dependence on supplemental parenteral support for a minimum of 60 days within a 74 consecutive day interval.↗
▶Ep 108 · 0:26
quoteThe reduction of functioning intestinal mass below that which can sustain life, resulting in dependence of supplemental parental support for a minimum of 60 days within a 74 consecutive day interval.↗
▶Ep 108 · 0:26
quoteThe reduction of functioning intestinal mass below that which can sustain life, resulting in dependence of supplemental parental support for a minimum of 60 days within a 74 consecutive day interval.↗
▶Ep 108 · 0:26
clinicalIntestinal failure is defined as the reduction of functioning intestinal mass below that which can sustain life, resulting in dependence on supplemental parenteral support for a minimum of 60 days within a 74 consecutive day interval.↗
▶Ep 108 · 0:43
quoteMore than 50% of the cases that we see are related to short bowel syndrome, some mucosal enteropathies and some dysmotility disorders.↗
▶Ep 108 · 0:43
epidemiologicalMore than 50% of intestinal failure cases are related to short bowel syndrome, with additional cases from mucosal enteropathies and dysmotility disorders.↗
▶Ep 108 · 0:43
epidemiologicalMore than 50% of intestinal failure cases are related to short bowel syndrome, with additional cases from mucosal enteropathies and dysmotility disorders.↗
▶Ep 108 · 0:43
quoteMore than 50% of the cases that we see are related to short bowel syndrome, some mucosal enteropathies and some dysmotility disorders.↗
▶Ep 108 · 0:55
clinicalMost causes of short bowel syndrome in pediatrics occur during the neonatal period, including gastroschisis, necrotizing enterocolitis, bowel atresia, and intestinal volvulus.↗
▶Ep 108 · 0:55
clinicalMost causes of short bowel syndrome in pediatrics occur during the neonatal period, including gastroschisis, necrotizing enterocolitis, bowel atresia, and intestinal volvulus.↗
▶Ep 108 · 1:18
opinionThe field is now focusing on neurocognitive outcomes, quality of life, and caregiver burnout as more children survive intestinal failure.↗
▶Ep 108 · 1:18
quoteThe field is starting to focus on neurocognitive outcomes, quality of life, and caregiver burnout.↗
▶Ep 108 · 1:18
quoteThe field is starting to focus on neurocognitive outcomes, quality of life, and caregiver burnout.↗
▶Ep 108 · 1:18
opinionThe field is now focusing on neurocognitive outcomes, quality of life, and caregiver burnout as more children survive intestinal failure.↗
clinicalIntestinal rehabilitation treatment strategy lacks clear-cut guidelines because every patient is unique with different gestational age, bowel resection, anatomy, and comorbidities.↗
▶Ep 108 · 1:48
clinicalIntestinal rehabilitation treatment strategy lacks clear-cut guidelines because every patient is unique with different gestational age, bowel resection, anatomy, and comorbidities.↗
▶Ep 108 · 1:52
quoteWe don't have a clear-cut guideline because every patient is extremely unique, born in a different gestational age, had a different bowel resection, has a different anatomy, different set of comorbidities.↗
▶Ep 108 · 1:52
quoteWe don't have a clear-cut guideline because every patient is extremely unique, born in a different gestational age, had a different bowel resection, has a different anatomy, different set of comorbidities.↗
▶Ep 108 · 2:07
quoteThe goal is to optimize intestinal function and adaptation before the development of irreversible complications.↗
▶Ep 108 · 2:07
clinicalThe goal of intestinal rehabilitation is to optimize intestinal function and adaptation before the development of irreversible complications.↗
▶Ep 108 · 2:07
quoteThe goal is to optimize intestinal function and adaptation before the development of irreversible complications.↗
▶Ep 108 · 2:07
clinicalThe goal of intestinal rehabilitation is to optimize intestinal function and adaptation before the development of irreversible complications.↗
▶Ep 108 · 2:30
clinicalIntestinal adaptation is an active compensatory process that starts immediately after bowel resection.↗
▶Ep 108 · 2:30
quoteIntestinal adaptation is an active process, is a compensatory process that starts happening right after bowel resection.↗
▶Ep 108 · 2:30
clinicalIntestinal adaptation is an active compensatory process that starts immediately after bowel resection.↗
▶Ep 108 · 2:30
quoteIntestinal adaptation is an active process, is a compensatory process that starts happening right after bowel resection.↗
▶Ep 108 · 2:42
quoteFood, bacteria and hormones in the gut is important.↗
▶Ep 108 · 2:42
clinicalFood, bacteria, and hormones in the gut are important factors that enhance intestinal adaptation.↗
▶Ep 108 · 2:42
clinicalFood, bacteria, and hormones in the gut are important factors that enhance intestinal adaptation.↗
▶Ep 108 · 2:42
quoteFood, bacteria and hormones in the gut is important.↗
▶Ep 108 · 2:45
quoteWe are trying to regain function of the bowel, so eventually the person doesn't need TPN anymore.↗
▶Ep 108 · 2:45
quoteWe are trying to regain function of the bowel, so eventually the person doesn't need TPN anymore.↗
▶Ep 108 · 3:11
clinicalEnteral autonomy is defined as getting off TPN with all nutrition going to the gut, either by mouth or by feeding tube.↗
▶Ep 108 · 3:11
quoteInternal autonomy is getting off TPN, having all your nutrition going to your gut, either by mouth or by a feeding tube.↗
▶Ep 108 · 3:11
quoteInternal autonomy is getting off TPN, having all your nutrition going to your gut, either by mouth or by a feeding tube.↗
▶Ep 108 · 3:11
clinicalEnteral autonomy is defined as getting off TPN with all nutrition going to the gut, either by mouth or by feeding tube.↗
▶Ep 108 · 3:33
epidemiologicalFrom 2010 to 2015, a repeat study with double the number of patients showed approximately 50% still reached enteral autonomy, but the number of transplants and deaths significantly decreased.↗
▶Ep 108 · 3:33
quoteFrom 2010 to 2015, that study was repeated with double the number of patients and still about 50% reached enter autonomy. But the number of transplants significantly decreased as well as death.↗
▶Ep 108 · 3:33
epidemiologicalFrom 2010 to 2015, a repeat study with double the number of patients showed approximately 50% still reached enteral autonomy, but the number of transplants and deaths significantly decreased.↗
▶Ep 108 · 3:33
quoteFrom 2010 to 2015, that study was repeated with double the number of patients and still about 50% reached enter autonomy. But the number of transplants significantly decreased as well as death.↗
▶Ep 108 · 3:46
quoteOne of the things that changed the outcome is the establishment of multidisciplinary teams.↗
▶Ep 108 · 3:46
clinicalThe establishment of multidisciplinary teams is one factor that changed outcomes in intestinal failure.↗
▶Ep 108 · 3:46
quoteOne of the things that changed the outcome is the establishment of multidisciplinary teams.↗
▶Ep 108 · 3:46
clinicalThe establishment of multidisciplinary teams is one factor that changed outcomes in intestinal failure.↗
▶Ep 108 · 4:03
clinicalPredictors of reaching enteral autonomy include residual bowel length (more is better), follow-up at an institution with an intestinal rehabilitation program, and no STEP procedure.↗
▶Ep 108 · 4:03
quoteThe residue is more about length, the more about, the better. Follow up on an institution that has an IR program and no-step procedure.↗
▶Ep 108 · 4:03
quoteThe residue is more about length, the more about, the better. Follow up on an institution that has an IR program and no-step procedure.↗
▶Ep 108 · 4:03
clinicalPredictors of reaching enteral autonomy include residual bowel length (more is better), follow-up at an institution with an intestinal rehabilitation program, and no STEP procedure.↗
▶Ep 108 · 4:19
guidelinePatients should be referred to intestinal rehabilitation programs when not making progress, on prolonged TPN, or have significant comorbidities, preferably sooner rather than later.↗
▶Ep 108 · 4:19
guidelinePatients should be referred to intestinal rehabilitation programs when not making progress, on prolonged TPN, or have significant comorbidities, preferably sooner rather than later.↗
▶Ep 108 · 4:19
quoteIf any physician has a patient with intestinal failure, we can consult at any point and provide support. But definitely, patients that are not making progress, that are on prolonged TPN have significant comorbidities, you wanna make sure you refer them sooner than later.↗
▶Ep 108 · 4:19
quoteIf any physician has a patient with intestinal failure, we can consult at any point and provide support. But definitely, patients that are not making progress, that are on prolonged TPN have significant comorbidities, you wanna make sure you refer them sooner than later.↗
▶Ep 108 · 4:39
quoteYou don't want to refer them when several complications already happened and now there's not a lot we can do other than transplant.↗
▶Ep 108 · 4:39
guidelinePatients should not be referred to intestinal rehabilitation when several irreversible complications have already occurred and transplant is the only remaining option.↗
▶Ep 108 · 4:39
quoteYou don't want to refer them when several complications already happened and now there's not a lot we can do other than transplant.↗
▶Ep 108 · 4:39
guidelinePatients should not be referred to intestinal rehabilitation when several irreversible complications have already occurred and transplant is the only remaining option.↗
▶Ep 108 · 4:49
clinicalIntestinal transplantation is considered when there are irreversible complications, though the number of transplants has significantly decreased over the last several decades.↗
▶Ep 108 · 4:49
quoteWe transplant when we have irreversible complications, or we have so many things to do to avoid that. The number of transplants has significantly decreased over the last several decades.↗
▶Ep 108 · 4:49
clinicalIntestinal transplantation is considered when there are irreversible complications, though the number of transplants has significantly decreased over the last several decades.↗
▶Ep 108 · 4:49
quoteWe transplant when we have irreversible complications, or we have so many things to do to avoid that. The number of transplants has significantly decreased over the last several decades.↗