StayCurrentMD · Gastoesophageal Reflux: Update Course 2015
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Video30 min·Published Nov 2018Older

Gastoesophageal Reflux: Update Course 2015

With Dr. Mac Harmon & Dr. Whitt Holcomb & Dr. Dan von Almen · hosted by Dr. Todd Ponsky · StayCurrentMD
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What the experts said15 expert statements · 13 host summaries
Children who wretch preoperatively have high likelihood of wretching postoperatively after fundoplication
Clinical
There is a 95% chance fundoplication will be done successfully without need for another operation
ClinicalWhit Holcomb
Fundoplication is clinically 95% successful, though literature reports much higher failure rates depending on how recurrence is assessed
Clinical
Immediate morbidity and mortality of laparoscopic fundoplication, even in infants, is very low and it is a safe operation
ClinicalDaniel von Allmen
EE is less likely in infants given how early in the feeding process they are, but has been seen in very young children
ClinicalGreg
Unrecognized motility disorders can be exacerbated by fundoplication, creating a functional obstruction that makes the situation more difficult
ClinicalGreg
Eosinophilic esophagitis is becoming an issue across the board as the frequency of food allergies is skyrocketing in the pediatric population
EpidemiologicalGreg
PPIs do not stop vomiting; they make refluxed material less acidic
ClinicalDaniel von Allmen
Long-term complications of laparotomy including bowel obstruction several years after open Nissen are underreported, with morbidity and even mortality from bowel obstruction related to laparotomy
Clinical
The laparoscopic fundoplication should be the same operation done openly, just performed laparoscopically, so results should be the same
Opinion
Whichever fundoplication technique (complete or partial) a surgeon does best, they should perform that technique
OpinionWhit Holcomb
Transmigration was 90% of the reasons for needing to redo fundoplications in Birmingham and Kansas City practices
ClinicalMac Harmon
Trial of bolus NG tube feeding predicts whether infant needs fundoplication: if they do well with NG tube, perform G-tube alone; if they don't, perform Nissen
ClinicalDaniel von Allmen
Bolus gastric feeding trial is the most helpful functional test for determining need for fundoplication, more informative than pH impedance probes
ClinicalWhit Holcomb
There is probably a 10-15% incidence of patients needing fundoplication after initial G-tube placement
ClinicalWhit Holcomb
Gastroesophageal reflux occurs in more than two-thirds of otherwise healthy infants and is discussed at 25% of all 6-month pediatric visits
Host summaryMac Harmon · not cited in answers
2009 NASPGHAN and ESPGHAN guidelines state surgical approaches should be reserved for children with intractable symptoms unresponsive to medical therapy and those at risk for life-threatening complications of reflux disease
Host summaryMac Harmon · not cited in answers
In adult literature, after about 15 years almost all fundoplications are undone
Host summaryDaniel von Allmen · not cited in answers
AAP guidelines note H2 antagonists or PPIs may have risk factors for pneumonia, gastroenteritis, candidemia, and NEC in preterm infants
Host summaryMac Harmon · not cited in answers
Meta-analysis of 400 fundoplications versus 125 gastrojejunostomy tubes showed no difference in pneumonia rate or mortality, but 29% major complications in fundo group versus lower rate in GJ group, and 70% minor complications in GJ group
Host summaryMac Harmon · not cited in answers
RCT of 44 laparoscopic versus 43 open fundoplications showed recurrence of reflux was 37% in laparoscopic group and only 7% in open group, with 5.2% higher risk of recurrence in laparoscopic group
Host summaryMac Harmon · not cited in answers
RCT of laparoscopic versus open fundoplication in children under age 2 (21 open, 18 laparoscopic over 7 years) showed no difference in length of stay, time to full feeds, or analgesic requirements, but laparoscopic had longer operative time and higher surgical charges
Host summaryMac Harmon · not cited in answers
Neurologically impaired patients do worse than neurologically normal patients after fundoplication according to historical data
Host summaryDaniel von Allmen · not cited in answers
Meta-analysis showed improved outcomes following complete fundoplication compared to partial wrap, though the difference was barely significant
Host summaryMac Harmon · not cited in answers
Kansas City/Birmingham prospective RCT showed aggressive esophageal mobilization had 23% to 37% incidence of transmigration over 6.5 years, while minimal mobilization increased from 3% to 12%
Host summaryWhit Holcomb · not cited in answers
Time to diagnosis of hiatal hernia was significantly longer in minimal mobilization group compared to maximum mobilization group
Host summaryWhit Holcomb · not cited in answers
There was no significant difference in reflux symptoms or medication use between minimal and maximal mobilization groups at 6.5 years
Host summaryWhit Holcomb · not cited in answers
Study showed 4% incidence of changes on upper GI prior to G-tube placement, with 80% of that 4% due to malrotation
Host summaryMac Harmon · not cited in answers