StayCurrentMD · Abdominal Wall Defects
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Video37 min·Published Nov 2018Older

Abdominal Wall Defects

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What the experts said37 expert statements · 3 host summaries
Most damage to the intestine in gastroschisis occurs in the last few weeks of pregnancy, supported by animal and clinical studies.
Clinical
Delivering gastroschisis at 37 weeks results in better neonatal outcomes compared to waiting for spontaneous labor.
Clinical
The age at spontaneous onset of labor for gastroschisis pregnancy is 3 weeks earlier than the general population.
Epidemiological
About half of gastroschisis pregnancies go into labor spontaneously before 37 weeks.
Epidemiological
No perinatal center in Canada performs routine cesarean sections for gastroschisis.
Epidemiological
Routine cesarean section for gastroschisis was standard of care 15-20 years ago but has gone out of favor.
Guideline
Using forceps and retractors for bedside reduction can harm the bowel in some cases.
Clinical
A pre-formed silo allows gentle reduction of gastroschisis contents without harming the bowel, and in about one-third of cases the bowel can be reduced immediately and the silo removed.
Clinical
Waiting for the neonate to lose 10% of body weight reduces bowel edema and makes reduction easier.
Clinical
Leaving a silo on for more than one day causes the fascial defect to enlarge significantly.
Clinical
A larger fascial defect after silo removal takes longer to contract and heal if not surgically closed.
Clinical
Rafensberger's group closed 80% of gastroschisis cases primarily; current practice has decreased to one-third to one-half primary closures.
Epidemiological
Plastic closure (non-surgical closure with dressing) produces extremely good results for gastroschisis, often with a small umbilical hernia that closes by age 2 in the vast majority of cases.
Clinical
Plastic closure avoids the need for operating room and general anesthesia in successful bedside reductions.
Clinical
Primary repair of atresia in gastroschisis is appropriate when the bowel does not look damaged.
Clinical
If the bowel looks nasty or matted, the atresia should be managed by reduction and delayed repair at 6 weeks.
Clinical
There are two types of intestinal atresia in gastroschisis: early-developing atresia not always associated with bowel thickening, and late atresia due to very small abdominal wall defect.
Clinical
Bringing an ostomy out through the umbilicus avoids a lateral scar and makes appliance placement easier.
Clinical
Gord Cameron first described umbilical ostomies in the 1980s.
Epidemiological
A mechanical stricture causing feeding intolerance after gastroschisis repair, when fixed surgically, can result in full feeds within 1-2 weeks.
Clinical
At 4 weeks post-gastroschisis repair with feeding intolerance, waiting longer is reasonable; at 8 weeks, exploration is warranted.
Opinion
Removing the omphalocele sac and attempting closure can lead to inability to achieve closure and need for prosthetic patch.
Clinical
A partially ruptured omphalocele sac can be closed and painted, functioning as an autogenous silo.
Clinical
Schuster-type repair uses mesh sutured to fascia with gradual closure over the intact sac, eventually allowing primary repair.
Clinical
For large omphalocele in a full-term baby with no other problems, staged closure with patch and skin coverage is preferable to paint-and-wait, which takes months.
Opinion
Lateral component separation can facilitate bringing fascial edges together in omphalocele closure.
Clinical
Keeping the omphalocele sac supple with antibiotic ointment, applying stacked 4x4s, and wrapping with Ace wrap can facilitate gradual reduction.
Clinical
Aquacel applied to omphalocele sac is not recommended as it does not come off easily.
Opinion
Pharmacy may restrict silver sulfadiazine use in the first month due to sulfa interaction concerns.
Guideline
Ventilatory parameters are the most reliable measure of safe abdominal closure tension.
Opinion
Bladder pressure measurement is standard practice at Cincinnati Children's for 24 hours post-closure, though its reliability is questioned.
Clinical
Intragastric pressure via NG tube is easy to measure intraoperatively and provides a useful guide, with 20 mmHg as a suggested threshold.
Clinical
Intragastric pressure of 12 mmHg with a stable baby provides reassurance that closure is safe; pressure of 35-40 mmHg raises concern even if the baby appears stable.
Clinical
Omphaloceles with a big opening and much content externalized often reduce spontaneously over 6-12 months with paint-and-wait, making eventual closure straightforward.
Clinical
Omphaloceles with a narrow opening require staged enlargement of the defect to allow gradual reduction over 2-3 stages without need for patch or component separation.
Clinical
In older children with giant omphalocele, rapid reduction can cause abdominal compartment syndrome and death; time must be allowed for abdominal domain expansion.
Clinical
When enlarging the fascial defect in a giant omphalocele with liver externalized, the inferior direction is safer to avoid hepatic veins superiorly.
Clinical
Wrapping Duoderm around an omphalocele and tightening daily can achieve gradual reduction without sutures.
Host summary
Botox has been used successfully in adult ventral hernia repair to relax muscle and facilitate closure.
Host summary
Silver sulfadiazine is commonly used to paint omphaloceles, though some use Betadine initially or Xerform.
Host summary