StayCurrentMD · Introduction and Panel Discussion: EA & TEF
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Video36 min·Published Dec 2012Older

Introduction and Panel Discussion: EA & TEF

With Dr. Todd Ponsky · hosted by Dr. Todd Ponsky

Chapter 1 of 4 · Surgical Management

Bronchoscopy debate

Surgical approach and preoperative bronchoscopy debate

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What the experts said34 expert statements · 8 host summaries
Cameron Haight's first successful EA repair in 1941 used a left chest approach with rib resection and extrapleural dissection due to lack of antibiotics.
Clinical
Transpleural versus retropleural approach makes no difference in modern practice with antibiotics.
Opinion
Placing a stitch through the tip of the upper pouch and the replogle tube allows traction on the tube rather than the esophagus, helping visualize the plane between membranous trachea and upper pouch.
Clinical
When uncertain of the plane between trachea and esophagus, err on the side of cutting a little esophageal muscle rather than risking tracheal injury.
Clinical
Complete dissection of the upper pouch all the way into the neck is necessary to detect a proximal fistula if present.
ClinicalJack
Water-soluble contrast study of the upper pouch can detect proximal fistula by showing dye entering the trachea or by revealing a narrower-than-expected upper pouch.
Clinical
Proximal fistulas are more common than realized, and some cases labeled as pure long-gap EA actually have an upper pouch fistula.
Clinical
The most urgent part of EA/TEF surgery is gaining control of the distal fistula before the baby decompensates.
OpinionSteve
Incidence of proximal fistula in the speaker's 20-year experience is one case.
EpidemiologicalSteve
During dissection between upper pouch and membranous trachea, a proximal fistula can be pushed out of the way and missed, especially since they sit at the cervicothoracic junction.
ClinicalMiguel
At least three patients referred for 'recurrent' TEF actually had missed upper pouch fistulas, which are easier to repair than true recurrences.
ClinicalTodd Ponsky
If the incidence of additional upper fistula is 5–8%, then 95% of bronchoscopies are performed without benefit.
EpidemiologicalSteve
Contrast studies carry risk of aspiration and contrast spillover if not performed carefully by an experienced operator.
ClinicalHolger
If performing a contrast study, the surgeon must do it personally under fluoroscopy, using maximum 1.5 cc of contrast and immediately evacuating it.
Clinical
Preoperative tracheobronchoscopy assesses vocal cord motility and measures the gap, which is important because more than 50% of long gaps occur in type C EA.
Clinical
In standard type C EA with distal fistula, the incidence of upper pouch fistula is 1–2%, whereas in EA without distal fistula (no gas in stomach), the incidence is 13–15%.
EpidemiologicalLouis
Bronchoscopy is mandatory in EA without distal fistula due to higher proximal fistula incidence, but selective in routine type C cases.
OpinionLouis
In type C EA, the distal fistula must be ligated regardless, allowing direct intraoperative evaluation of the upper pouch and gap, making preoperative bronchoscopy less critical.
OpinionSteve
Meta-analyses of long-gap EA are difficult to interpret because studies use inconsistent definitions of 'long gap'; some papers label 2.5 cm gaps as long gap, which most surgeons would not.
ClinicalTodd Ponsky
The primary goal in EA repair is minimizing tension on the anastomosis to prevent leaks; 70% of recurrent TEFs in one series had a previous anastomotic leak.
Clinical
Distal pouch should be dissected as extensively as the upper pouch, even down to the crura if necessary, to reduce anastomotic tension.
Clinical
The belief that blood supply to the lower pouch comes directly from aortic branches is a myth; extensive dissection rarely causes significant bleeding.
ClinicalLouis
During distal pouch dissection, significant bleeding from vessels is rarely observed.
Clinical
The main branches of the vagus nerve can be preserved during distal pouch mobilization, especially with thoracoscopic magnification.
ClinicalSteve
The esophagus in EA is not normally innervated even before repair; expecting normal motility after anastomosis is unrealistic regardless of vagal branch preservation.
OpinionSteve
Patients with uncomplicated type C EA repairs still exhibit dysmotility and can present with food impaction despite having no stricture.
ClinicalSteve
Surgical outcome and esophageal peristalsis vary widely among patients despite identical surgical technique, suggesting intrinsic esophageal factors rather than surgical dissection determine motility.
OpinionMiguel
Thoracoscopic dissection of the distal pouch reveals in magnified view that no significant vessels enter the distal pouch.
ClinicalSteve
The primary clinical problems post-EA repair are short esophagus with reflux and stricture formation, not inability to eat.
ClinicalSteve
Current knowledge of esophageal innervation in EA is insufficient to categorically state that vagal branches must be preserved.
Opinion
Dissecting the esophagus for other (non-EA) conditions does not typically result in postoperative dysmotility.
Clinical
Anastomoses performed under extreme tension with elective paralysis and ventilation for 5 days resulted in zero leaks in one series over 20 years.
ClinicalLouis
During 5–7 days of paralysis and intubation, the esophagus under tension grows substantially, reducing tension rather than simply preserving the anastomosis.
ClinicalJack
About two-thirds of esophageal peristaltic function is conducted through the muscle layers; fibrous healing at the anastomosis interrupts this wave, leaving sporadic contractions that are usually sufficient for esophageal emptying.
ClinicalJack
Most surgeons use a muscle-sparing incision for open TEF repair.
Host summaryThe host summarizing the discussion · not cited in answers
Extrapleural approach may provide easier exposure because a single retractor can hold all three lung lobes out of the way.
Host summaryTodd Ponsky summarizing the discussion · not cited in answers
In thoracoscopic repair, lung collapse eliminates the need for retraction, making the transpleural approach a non-issue.
Host summaryTodd Ponsky summarizing the discussion · not cited in answers
Bronchoscopy before surgery is important to determine if a proximal fistula is present.
Host summaryTodd Ponsky summarizing the discussion · not cited in answers
A shorter upper pouch increases the likelihood of a proximal fistula.
Host summarySteve summarizing the discussion · not cited in answers
Bronchoscopy helps identify where the fistula inserts into the trachea, which is useful for surgical planning and fellow training.
Host summaryTodd Ponsky summarizing the discussion · not cited in answers
A Japanese study using manometry pre-repair found normal peristalsis in both proximal and distal pouches (accessed via gastrostomy), which was disrupted post-repair.
Host summaryJack summarizing the discussion · not cited in answers
Anastomotic strength is weakest at 5–7 days postoperatively, which coincides with typical extubation timing.
Host summaryTodd Ponsky summarizing the discussion · not cited in answers