StayCurrentMD · Update Course Rewind: Perforated Appendicitis 2019
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Podcast12 min·Published Apr 2021Older

Update Course Rewind: Perforated Appendicitis 2019

With Dr. Whit Holcomb & Dr. Matt Carbon & Dr. Alex Gibbons · hosted by Dr. Rod Gerardo

Chapter 1 of 5 · Fundamentals

Introduction

Introduction and Clinical Context

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What the experts said3 expert statements · 9 host summaries
Both groups in the irrigation trial had abscess rates of 18% and 19%, which are higher than some other studies
ClinicalMatt Carbon
The higher abscess rates in the irrigation trial may be due to the specific definition of perforation used at that institution
OpinionWhit Holcomb
The best quality study on irrigation showed no difference in outcomes, while a more recent but less well-designed study showed a difference favoring standardized large-volume irrigation
OpinionWhit Holcomb
CT scan reviewers (6 surgeons including 2 fellows and 2 radiologists) were only 72% accurate in distinguishing perforated from non-perforated appendicitis when reviewing 200 CT scans
Host summaryRod Gerardo summarizing the discussion · not cited in answers
Among 62 attending surgeons (adult and pediatric, from university, community, and children's hospitals), agreement in defining intraoperative laparoscopic images as perforated or non-perforated appendicitis was 27%
Host summaryRod Gerardo summarizing the discussion · not cited in answers
Inter and intra-observer variability in assessing perforation from intraoperative images was close to chance alone, with surgeons not agreeing with themselves when shown the same image flipped and rotated
Host summaryWhit Holcomb summarizing the discussion · not cited in answers
A standardized definition of perforated appendicitis as a hole in the appendix or a fecalith in the abdomen was implemented at one hospital
Host summaryRod Gerardo summarizing the discussion · not cited in answers
Patients without a hole in the appendix or fecalith in the abdomen had an incidence of postoperative abscess less than 5%
Host summaryRod Gerardo summarizing the discussion · not cited in answers
After implementing a standardized definition for perforated appendicitis, the non-perforation abscess rate decreased and the perforation abscess rate increased, suggesting previous misclassification
Host summaryRod Gerardo summarizing the discussion · not cited in answers
In a randomized trial with 110 patients per arm, irrigation with minimum 500cc (average 850cc) showed no difference in postoperative abscess rate, length of stay, hospital cost, or operative time compared to no irrigation
Host summaryRod Gerardo summarizing the discussion · not cited in answers
A study comparing standardized large-volume irrigation (3-12L in small focused aliquots) to surgeon preference showed 0% abscess rate with standardized irrigation versus 19% with surgeon discretion
Host summaryWhit Holcomb summarizing the discussion · not cited in answers
A 2018 meta-analysis comparing suction alone versus irrigation in children and adults found no difference in postoperative abscess rates
Host summaryWhit Holcomb summarizing the discussion · not cited in answers