Alex Halpern

206 statements · 21 topics · summaries given as host listed separately

Featured statements

They found that children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group, showing that standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery.
So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
So it seems like both of these options have their pros and cons with the intercostal nerve co ablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
So, it seems like same day discharge for pediatric patients after elective laparoscopic gastrostomy is safe, but not commonly done.
So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients.
Studies agreed that transitional care should start early in adolescence

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Alex's statements about Abdominal Wall Defects 5 statements

Open the Abdominal Wall Defects collection →

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Quotation Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis? Open
Quotation Does this information change your practice at all? Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Quotation What is the optimal initial management of an infant with gastroschisis? Open
Quotation Does this information change your practice at all? Open

Quick Literature Updates Ep 22

Quotation Does this information change your practice at all? Open
Alex's statements about Anorectal Malformation 8 statements

Open the Anorectal Malformation collection →

Transition From Pediatric to Adult Healthcare for Colorectal Conditions: A Systematic Review

Statement Patients with anorectal malformations and Hirschsprung's disease need transfer from pediatric to adult providers to manage their colorectal conditions Open
Statement A team from Melbourne, Australia performed a systematic review and meta-analysis on transition of care for these conditions Open
Statement Eight studies were found on the topic of transition care for anorectal malformations and Hirschsprung's disease Open
Statement Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion Open
Statement Studies agreed that transitional care should start early in adolescence Open
Statement No models of transition care were identified in the systematic review Open
Statement More work is needed to ensure children with anorectal malformations and Hirschsprung's disease continue to receive optimal care as they grow older Open
Quotation Does this information change your practice at all? Open
Alex's statements about Cancer 10 statements

Open the Cancer collection →

Female Fertility Cryopreservation Outcomes in Childhood Cancer: A Systematic Review

Quotation What does the current literature say about outcomes of female fertility cryopreservation in children with cancer? Open
Statement Gillippelli et al. performed a systematic retrospective review of female fertility cryopreservation outcomes in children with cancer Open
Statement The review initially examined 104 abstracts and 34 full text articles Open
Statement 12 studies were included in the final systematic review Open
Statement Ovarian tissue cryopreservation was performed in 501 patients across the included studies Open
Statement 5.9% of patients who underwent ovarian tissue cryopreservation later received ovarian tissue transplantation Open
Statement 33% of patients who underwent ovarian tissue transplantation were able to become pregnant Open
Quotation So, it seems like ovarian tissue cryopreservation has great advantages for pediatric cancer patients, but needs to be studied further. Open
Statement Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further Open
Quotation Does this information change your practice at all? Open
Alex's statements about Choledocholithiasis 9 statements

Open the Choledocholithiasis collection →

Multi-Institutional Analysis of Choledocholithiasis in Pediatric vs Adult Patients

Quotation Can a surgery first approach be used for the management of cholodocholithiasis in children? Open
Statement Dantes et al. performed a multi-center retrospective review of pediatric and adult patients treated for choledocholithiasis between 2018 and 2024 Open
Statement 724 patients were included in the study Open
Statement Surgery first approach with upfront laparoscopic cholecystectomy with intraoperative cholangiogram was performed in 201 pediatric patients and 169 adult patients Open
Statement Laparoscopic common bile duct exploration was attempted in 84 children and 140 adults in the surgery first group Open
Statement Common bile duct exploration success was higher in pediatric than adult patients Open
Statement Complication rates were similar between pediatric and adult patients in the surgery first approach Open
Statement A surgery first approach can be a safe and effective tool for managing choledocholithiasis in pediatric patients Open
Quotation Does this information change your practice? Open
Alex's statements about Colorectal / ARM & Hirschsprung 38 statements

Open the Colorectal / ARM & Hirschsprung collection →

Standardized perioperative care reduces colorectal surgical site infection in children

Statement Surgical site infections are a major cause of perioperative morbidity in children undergoing colorectal surgery Open
Quotation Surgical site infections are a major cause of perioperative morbidity in children undergoing colorectal surgery. Open
Statement The Western Pediatric Surgery Research Consortium conducted a prospective cohort study on children undergoing colorectal surgery across 10 hospitals in the US Open
Statement The study utilized an 8-part perioperative care bundle Open
Statement Children were split into either a high or low compliance group based on adherence to the care bundle Open
Statement Children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group Open
Statement Standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery Open
Quotation They found that children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group, showing that standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery. Open

Quick Literature Updates Episode 14

Statement Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum. Open
Quotation Now, what are the benefits of each? Open
Statement Dr. Tsai and his team from Penn State conducted a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020, comparing outcomes and costs of intercostal nerve cryoablation and epidural. Open
Statement The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural. Open
Statement The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural. Open
Statement The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural. Open
Statement The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural. Open
Statement The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural. Open
Quotation So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost. Open
Statement Both intercostal nerve cryoablation and thoracic epidural have pros and cons, with cryoablation showing decreased total opioid use and decreased length of stay but increased operating room times and increased total cost. Open

Transition From Pediatric to Adult Healthcare for Colorectal Conditions: A Systematic Review

Statement Patients with anorectal malformations and Hirschsprung's disease need transfer from pediatric to adult providers to manage their colorectal conditions Open
Statement A team from Melbourne, Australia performed a systematic review and meta-analysis on transition of care for these conditions Open
Statement Eight studies were found on the topic of transition care for anorectal malformations and Hirschsprung's disease Open
Statement Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion Open
Statement Studies agreed that transitional care should start early in adolescence Open
Statement No models of transition care were identified in the systematic review Open
Statement More work is needed to ensure children with anorectal malformations and Hirschsprung's disease continue to receive optimal care as they grow older Open
Quotation Does this information change your practice at all? Open

Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Quotation Does delayed diagnosis of Hirschrung disease affect postoperative and functional outcomes? Open
Statement The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes. Open
Statement The study included 679 patients with Hirschsprung disease from 14 different sites. Open
Statement Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. Open
Statement Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. Open
Statement No association was found between age at diagnosis and 30-day complication rate after initial pull-through. Open
Statement No association was found between age at diagnosis and need for pull-through revision. Open
Statement Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients. Open
Quotation Does this information change your practice at all? Open

Quick Literature Updates Episode 17

Statement Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients. Open
Quotation So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients. Open

Quick Literature Updates Ep 22

Quotation Does this information change your practice at all? Open
Alex's statements about Congenital Pulmonary Airway Malformation 4 statements

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Quick Literature Updates Episode 18

Statement Eight studies were found examining transition from pediatric to adult healthcare for colorectal conditions Open
Statement Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion Open
Statement Studies agreed that transitional care should start early in adolescence Open
Statement No models of transition care were identified for patients with anorectal malformations and Hirschsprung's disease Open
Alex's statements about Constipation 9 statements

Open the Constipation collection →

Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Quotation Does delayed diagnosis of Hirschrung disease affect postoperative and functional outcomes? Open
Statement The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes. Open
Statement The study included 679 patients with Hirschsprung disease from 14 different sites. Open
Statement Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. Open
Statement Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. Open
Statement No association was found between age at diagnosis and need for pull-through revision. Open
Statement No association was found between age at diagnosis and 30-day complication rate after initial pull-through. Open
Statement Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients. Open
Quotation Does this information change your practice at all? Open
Alex's statements about Esophageal Atresia 2 statements

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Quick Literature Updates Episode 17

Statement Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients. Open
Quotation So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients. Open
Alex's statements about Etiologies (Gastroschisis/NEC/Atresia/Volvulus) 7 statements

Open the Etiologies (Gastroschisis/NEC/Atresia/Volvulus) collection →

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Quotation Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis? Open
Quotation Does this information change your practice at all? Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Quotation What is the optimal initial management of an infant with gastroschisis? Open
Quotation Does this information change your practice at all? Open

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Quotation How big of a problem are intestinal strictures after conservative management of necrotizing enterocolitis? Open
Quotation Does this information change your practice at all? Open

Quick Literature Updates Ep 22

Quotation Does this information change your practice at all? Open
Alex's statements about Gastroschisis 3 statements

Open the Gastroschisis collection →

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Quotation What is the optimal initial management of an infant with gastroschisis? Open
Quotation Does this information change your practice at all? Open

Quick Literature Updates Ep 22

Quotation Does this information change your practice at all? Open
Alex's statements about Giant Omphalocele 6 statements

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Quick Literature Updates Episode 20

Statement Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric). Open
Statement Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device. Open
Statement Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device. Open
Statement No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric. Open
Statement No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric. Open
Quotation So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients. Open
Alex's statements about Hirschsprung disease 20 statements

Open the Hirschsprung disease collection →

Transition From Pediatric to Adult Healthcare for Colorectal Conditions: A Systematic Review

Statement Patients with anorectal malformations and Hirschsprung's disease need transfer from pediatric to adult providers to manage their colorectal conditions Open
Statement A team from Melbourne, Australia performed a systematic review and meta-analysis on transition of care for these conditions Open
Statement Eight studies were found on the topic of transition care for anorectal malformations and Hirschsprung's disease Open
Statement Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion Open
Statement Studies agreed that transitional care should start early in adolescence Open
Statement No models of transition care were identified in the systematic review Open
Statement More work is needed to ensure children with anorectal malformations and Hirschsprung's disease continue to receive optimal care as they grow older Open
Quotation Does this information change your practice at all? Open

Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Quotation Does delayed diagnosis of Hirschrung disease affect postoperative and functional outcomes? Open
Statement The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes. Open
Statement The study included 679 patients with Hirschsprung disease from 14 different sites. Open
Statement Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. Open
Statement Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. Open
Statement No association was found between age at diagnosis and need for pull-through revision. Open
Statement No association was found between age at diagnosis and 30-day complication rate after initial pull-through. Open
Statement Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients. Open
Quotation Does this information change your practice at all? Open

Quick Literature Updates Episode 17

Statement Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients. Open
Quotation So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients. Open

Quick Literature Updates Ep 22

Quotation Does this information change your practice at all? Open
Alex's statements about Intestinal Rehab 7 statements

Open the Intestinal Rehab collection →

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Quotation Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis? Open
Quotation Does this information change your practice at all? Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Quotation What is the optimal initial management of an infant with gastroschisis? Open
Quotation Does this information change your practice at all? Open

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Quotation How big of a problem are intestinal strictures after conservative management of necrotizing enterocolitis? Open
Quotation Does this information change your practice at all? Open

Quick Literature Updates Ep 22

Quotation Does this information change your practice at all? Open
Alex's statements about Necrotizing Enterocolitis 4 statements

Open the Necrotizing Enterocolitis collection →

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Quotation Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis? Open
Quotation Does this information change your practice at all? Open

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Quotation How big of a problem are intestinal strictures after conservative management of necrotizing enterocolitis? Open
Quotation Does this information change your practice at all? Open
Alex's statements about Pancreatitis 9 statements

Open the Pancreatitis collection →

Multi-Institutional Analysis of Choledocholithiasis in Pediatric vs Adult Patients

Quotation Can a surgery first approach be used for the management of cholodocholithiasis in children? Open
Statement Dantes et al. performed a multi-center retrospective review of pediatric and adult patients treated for choledocholithiasis between 2018 and 2024 Open
Statement 724 patients were included in the study Open
Statement Surgery first approach with upfront laparoscopic cholecystectomy with intraoperative cholangiogram was performed in 201 pediatric patients and 169 adult patients Open
Statement Laparoscopic common bile duct exploration was attempted in 84 children and 140 adults in the surgery first group Open
Statement Common bile duct exploration success was higher in pediatric than adult patients Open
Statement Complication rates were similar between pediatric and adult patients in the surgery first approach Open
Statement A surgery first approach can be a safe and effective tool for managing choledocholithiasis in pediatric patients Open
Quotation Does this information change your practice? Open
Alex's statements about Pectus Excavatum 21 statements

Open the Pectus Excavatum collection →

Cost and outcomes of intercostal nerve cryoablation versus thoracic epidural following the Nuss procedure

Statement Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum Open
Quotation Thoracic epidural and intercostal nerve coagabulations are two options for pain control in patients undergoing a NUS procedure for pectus excavatum. Open
Statement Dr. Tsai and his team from Penn State conducted a retrospective chart review looking at kids who underwent a Nuss procedure between 2002 and 2020 Open
Statement The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had higher total hospitalization cost than the thoracic epidural group Open
Statement Both intercostal nerve cryoablation and thoracic epidural have pros and cons for pain control following Nuss procedure Open
Quotation So it seems like both of these options have their pros and cons with the intercostal nerve co ablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost. Open

Vacuum Bell Therapy for Pectus Excavatum: Long-term Experience at a Single Center

Quotation What factors affect outcomes in patients with pectus excavatum treated with vacuum valve therapy? Open
Statement The study was a single institution retrospective chart review conducted from 2012 to 2023 Open
Statement 278 patients were included in the analysis Open
Statement 247 patients had non-excellent corrections with vacuum bell therapy Open
Statement 31 patients had excellent corrections with vacuum bell therapy Open
Statement Initial chest depth less than 1.5 centimeters is a predictor of positive outcomes Open
Statement Excellent correction was more common in children 8 to 12.9 years old Open
Statement Chest wall flexibility is a predictor of positive outcomes Open
Statement Improved outcomes are seen in younger patients with more mild defects and greater chest wall flexibility Open
Statement Excellent correction in children with pectus excavatum treated with vacuum bell therapy is uncommon Open
Quotation Does this information change your practice? Open
Alex's statements about Peritoneal Dialysis Access 7 statements

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Early Peritoneal Dialysis and Postoperative Outcomes in Infants After Pediatric Cardiac Surgery

Quotation Can early initiation of peritoneal dialysis after pediatric cardiac surgery improve outcomes? Open
Statement Dr. Dudike and his team performed a systematic review and meta-analysis on early peritoneal dialysis after pediatric cardiac surgery Open
Statement Five studies were included in the meta-analysis Open
Statement Early initiation of peritoneal dialysis was associated with decreased postoperative mortality Open
Statement Early initiation of peritoneal dialysis may benefit infants after pediatric cardiac surgery Open
Statement Early initiation of peritoneal dialysis shortened duration of mechanical ventilation Open
Statement Early initiation of peritoneal dialysis shortened length of stay in the ICU Open
Alex's statements about Sarcoma (Ewing/Rhabdo) 20 statements

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Female Fertility Cryopreservation Outcomes in Childhood Cancer: A Systematic Review

Quotation What does the current literature say about outcomes of female fertility cryopreservation in children with cancer? Open
Statement Gillippelli et al. performed a systematic retrospective review of female fertility cryopreservation outcomes in children with cancer Open
Statement 12 studies were included in the final systematic review Open
Statement The review initially examined 104 abstracts and 34 full text articles Open
Statement 5.9% of patients who underwent ovarian tissue cryopreservation later received ovarian tissue transplantation Open
Statement Ovarian tissue cryopreservation was performed in 501 patients across the included studies Open
Statement 33% of patients who underwent ovarian tissue transplantation were able to become pregnant Open
Quotation So, it seems like ovarian tissue cryopreservation has great advantages for pediatric cancer patients, but needs to be studied further. Open
Statement Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further Open
Quotation Does this information change your practice at all? Open

Same-Day Discharge for Elective Pediatric Laparoscopic Gastrostomy Tube Insertion is Safe and Increasing in Frequency; A NSQIP Pediatric Retrospective Review 2017 to 2021

Quotation What are the trends and outcomes of same-day discharge after pediatric elective laparoscopic gastrostomy? Open
Statement The study analyzed the ACS NSQIP Pediatric database from 2017 to 2021 Open
Statement 5,947 pediatric patients underwent elective laparoscopic gastrostomy tube placement in the study period Open
Statement 4.7% of patients were discharged the same day after laparoscopic gastrostomy tube placement Open
Statement There were no significant differences in 30-day unplanned readmissions between same-day discharge and 1-2 day discharge patients Open
Statement There were no significant differences in any other complications between same-day discharge and 1-2 day discharge patients Open
Statement There were no significant differences in reoperations between same-day discharge and 1-2 day discharge patients Open
Statement Same-day discharge for pediatric patients after elective laparoscopic gastrostomy appears to be safe Open
Quotation So, it seems like same day discharge for pediatric patients after elective laparoscopic gastrostomy is safe, but not commonly done. Open
Statement Same-day discharge after pediatric laparoscopic gastrostomy is not commonly done Open
Alex's statements about Surgical Site Infections 8 statements

Open the Surgical Site Infections collection →

Standardized perioperative care reduces colorectal surgical site infection in children

Quotation Surgical site infections are a major cause of perioperative morbidity in children undergoing colorectal surgery. Open
Statement Surgical site infections are a major cause of perioperative morbidity in children undergoing colorectal surgery Open
Statement The Western Pediatric Surgery Research Consortium conducted a prospective cohort study on children undergoing colorectal surgery across 10 hospitals in the US Open
Statement Children were split into either a high or low compliance group based on adherence to the care bundle Open
Statement The study utilized an 8-part perioperative care bundle Open
Quotation They found that children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group, showing that standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery. Open
Statement Standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery Open
Statement Children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group Open
Alex's statements about Trisomy 21 8 statements

Open the Trisomy 21 collection →

Quick Literature Updates Episode 14

Statement Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing Nuss procedure for pectus excavatum Open
Statement The study was a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020 Open
Statement The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural Open
Statement The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural Open
Quotation So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost. Open
Alex's statements about Wilms Tumor 1 statement

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Quick Literature Updates Ep 21

Quotation Does this information change your practice at all? Open

Summaries Alex gave as host · 341 summaries

Recaps of other experts' statements, not Alex's own clinical position.

Summaries Alex gave as host · Abdominal Wall Defects 42 summaries

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Quick Literature Updates Episode 11

Host summary Alex Halpern summarizing a resource: Pain control after appendectomy for perforated appendicitis can be a huge problem in kids. Open
Host summary Alex Halpern summarizing a resource: Could Gabapentin help with pain control in these kids? Open
Host summary Alex Halpern summarizing a resource: Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay. Open
Host summary Alex Halpern summarizing a resource: Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use. Open

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Host summary Alex Halpern summarizing a resource: McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes. Open
Host summary Alex Halpern summarizing a resource: Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis. Open

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Host summary Alex Halpern summarizing a resource: Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device. Open
Host summary Alex Halpern summarizing a resource: The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No patients developed abdominal compartment syndrome in the study. Open
Host summary Alex Halpern summarizing a resource: No ventral hernias occurred after a median follow-up of 12 months. Open
Host summary Alex Halpern summarizing a resource: Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects. Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Host summary Alex Halpern summarizing a resource: The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Delivery after 37 weeks is optimal for infants with gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe and effective. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients. Open
Host summary Alex Halpern summarizing a resource: There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis. Open

Quick Literature Updates Episode 16

Host summary Alex Halpern summarizing a resource: The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake. Open
Host summary Alex Halpern summarizing a resource: In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay. Open
Host summary Alex Halpern summarizing a resource: So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis. Open

Quick Literature Updates Episode 20

Host summary Alex Halpern summarizing a resource: Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric). Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device. Open
Host summary Alex Halpern summarizing a resource: No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric. Open
Host summary Alex Halpern summarizing a resource: No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric. Open
Host summary Alex Halpern summarizing a resource: So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients. Open

Quick Literature Updates Ep 22

Host summary Alex Halpern summarizing a resource: The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis. Open
Host summary Alex Halpern summarizing a resource: For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants. Open
Summaries Alex gave as host · Anorectal Malformation 23 summaries

Open the Anorectal Malformation collection →

Quick Literature Updates Episode 14

Host summary Alex Halpern summarizing a resource: Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum. Open
Host summary Alex Halpern summarizing a resource: Now, what are the benefits of each? Open
Host summary Alex Halpern summarizing a resource: Dr. Tsai and his team from Penn State conducted a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020, comparing outcomes and costs of intercostal nerve cryoablation and epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost. Open
Host summary Alex Halpern summarizing a resource: Both intercostal nerve cryoablation and thoracic epidural have pros and cons, with cryoablation showing decreased total opioid use and decreased length of stay but increased operating room times and increased total cost. Open

Quick Literature Updates Episode 18

Host summary Alex Halpern summarizing a resource: A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions. Open
Host summary Alex Halpern summarizing a resource: Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence. Open
Host summary Alex Halpern summarizing a resource: Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion. Open
Host summary Alex Halpern summarizing a resource: No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older. Open
Host summary Alex Halpern summarizing a resource: No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care. Open

Quick Literature Updates Ep 23

Host summary Alex Halpern summarizing a resource: A working group of pediatric surgeons from Europe created 19 case scenarios with unexpected events to validate the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: Surgeons within the European Reference Network of inherited and congenital anomalies rated scenarios based on the Clavien-Dindo classification or the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: A total of 59 surgeons completed the questionnaire. Open
Host summary Alex Halpern summarizing a resource: The Clavian-Matti classification showed significantly better agreement rates and was less frequently considered inaccurate. Open
Host summary Alex Halpern summarizing a resource: The Clavien-Madadi classification showed significantly better agreement rates and was less frequently considered inaccurate compared to Clavien-Dindo. Open
Host summary Alex Halpern summarizing a resource: More pediatric surgeons preferred using the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: The Clavien-Madadi classification is both an accurate and useful tool in grading unexpected events in pediatric surgery. Open
Host summary Alex Halpern summarizing a resource: So it seems like the Clavian-Matti classification is both an accurate and useful tool in grading unexpected events in pediatric surgery. Open
Summaries Alex gave as host · Appendicitis 6 summaries

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Quick Literature Updates Episode 11

Host summary Alex Halpern summarizing a resource: Pain control after appendectomy for perforated appendicitis can be a huge problem in kids. Open
Host summary Alex Halpern summarizing a resource: Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery. Open
Host summary Alex Halpern summarizing a resource: Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay. Open
Host summary Alex Halpern summarizing a resource: Could Gabapentin help with pain control in these kids? Open
Summaries Alex gave as host · Colorectal / ARM & Hirschsprung 40 summaries

Open the Colorectal / ARM & Hirschsprung collection →

Quick Literature Updates Episode 14

Host summary Alex Halpern summarizing a resource: Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum. Open
Host summary Alex Halpern summarizing a resource: Now, what are the benefits of each? Open
Host summary Alex Halpern summarizing a resource: Dr. Tsai and his team from Penn State conducted a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020, comparing outcomes and costs of intercostal nerve cryoablation and epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural. Open
Host summary Alex Halpern summarizing a resource: Both intercostal nerve cryoablation and thoracic epidural have pros and cons, with cryoablation showing decreased total opioid use and decreased length of stay but increased operating room times and increased total cost. Open
Host summary Alex Halpern summarizing a resource: So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost. Open

Quick Literature Updates Episode 17

Host summary Alex Halpern summarizing a resource: The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study included 679 patients from 14 different sites. Open
Host summary Alex Halpern summarizing a resource: Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. Open
Host summary Alex Halpern summarizing a resource: Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through. Open

Quick Literature Updates Episode 18

Host summary Alex Halpern summarizing a resource: A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions. Open
Host summary Alex Halpern summarizing a resource: Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion. Open
Host summary Alex Halpern summarizing a resource: Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence. Open
Host summary Alex Halpern summarizing a resource: No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older. Open
Host summary Alex Halpern summarizing a resource: No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care. Open

Quick Literature Updates Ep 22

Host summary Alex Halpern summarizing a resource: The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis. Open
Host summary Alex Halpern summarizing a resource: For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants. Open

Quick Literature Updates Ep 23

Host summary Alex Halpern summarizing a resource: A working group of pediatric surgeons from Europe created 19 case scenarios with unexpected events to validate the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: Surgeons within the European Reference Network of inherited and congenital anomalies rated scenarios based on the Clavien-Dindo classification or the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: A total of 59 surgeons completed the questionnaire. Open
Host summary Alex Halpern summarizing a resource: The Clavien-Madadi classification showed significantly better agreement rates and was less frequently considered inaccurate compared to Clavien-Dindo. Open
Host summary Alex Halpern summarizing a resource: The Clavian-Matti classification showed significantly better agreement rates and was less frequently considered inaccurate. Open
Host summary Alex Halpern summarizing a resource: More pediatric surgeons preferred using the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: So it seems like the Clavian-Matti classification is both an accurate and useful tool in grading unexpected events in pediatric surgery. Open
Host summary Alex Halpern summarizing a resource: The Clavien-Madadi classification is both an accurate and useful tool in grading unexpected events in pediatric surgery. Open

Quick Literature Updates Ep 26

Host summary Alex Halpern summarizing a resource: Zoo et al. used the PHIS database and performed a multi-institutional cohort study of all ARM patients between 2016 and 2022 Open
Host summary Alex Halpern summarizing a resource: In ARM patients, the rates of actual diagnoses across all hospital encounters were 45.4% vertebral spinal, 77.4% cardiac, 10.2% TEF, 39.9% renal and 15.7% limb Open
Host summary Alex Halpern summarizing a resource: 25.8% of female patients with anorectal malformations had a congenital gynecologic malformation diagnosed Open
Host summary Alex Halpern summarizing a resource: So it seems like the most common anomalies associated with ARMs are cardiac, vertebrospinal, renal, and gynecologic. Open
Host summary Alex Halpern summarizing a resource: The most common anomalies associated with ARMs are cardiac, vertebrospinal, renal, and gynecologic Open
Host summary Alex Halpern summarizing a resource: The authors of the ARM screening study suggest changing the VACTERL acronym to VACTERL-GS Open
Summaries Alex gave as host · Congenital Diaphragmatic Hernia 6 summaries

Open the Congenital Diaphragmatic Hernia collection →

Quick Literature Updates Episode 20

Host summary Alex Halpern summarizing a resource: Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric). Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device. Open
Host summary Alex Halpern summarizing a resource: No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric. Open
Host summary Alex Halpern summarizing a resource: No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric. Open
Host summary Alex Halpern summarizing a resource: So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients. Open
Summaries Alex gave as host · Congenital Lung Lesions (CPAM) 5 summaries

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Quick Literature Updates Episode 18

Host summary Alex Halpern summarizing a resource: A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions. Open
Host summary Alex Halpern summarizing a resource: Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion. Open
Host summary Alex Halpern summarizing a resource: Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence. Open
Host summary Alex Halpern summarizing a resource: No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older. Open
Host summary Alex Halpern summarizing a resource: No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care. Open
Summaries Alex gave as host · Esophageal Atresia 11 summaries

Open the Esophageal Atresia collection →

Quick Literature Updates Episode 17

Host summary Alex Halpern summarizing a resource: The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study included 679 patients from 14 different sites. Open
Host summary Alex Halpern summarizing a resource: Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. Open
Host summary Alex Halpern summarizing a resource: Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through. Open

Quick Literature Updates Ep 27

Host summary Alex Halpern summarizing a resource: Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis. Open
Host summary Alex Halpern summarizing a resource: So it seems like post-neck strictures are a common occurrence after conservative management of neck. Open
Summaries Alex gave as host · Etiologies (Gastroschisis/NEC/Atresia/Volvulus) 57 summaries

Open the Etiologies (Gastroschisis/NEC/Atresia/Volvulus) collection →

Quick Literature Updates Episode 11

Host summary Alex Halpern summarizing a resource: Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay. Open
Host summary Alex Halpern summarizing a resource: Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use. Open
Host summary Alex Halpern summarizing a resource: Pain control after appendectomy for perforated appendicitis can be a huge problem in kids. Open
Host summary Alex Halpern summarizing a resource: Could Gabapentin help with pain control in these kids? Open

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Host summary Alex Halpern summarizing a resource: McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes. Open
Host summary Alex Halpern summarizing a resource: Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis. Open

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Host summary Alex Halpern summarizing a resource: Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device. Open
Host summary Alex Halpern summarizing a resource: The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No patients developed abdominal compartment syndrome in the study. Open
Host summary Alex Halpern summarizing a resource: No ventral hernias occurred after a median follow-up of 12 months. Open
Host summary Alex Halpern summarizing a resource: Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects. Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Host summary Alex Halpern summarizing a resource: The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Delivery after 37 weeks is optimal for infants with gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe and effective. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients. Open
Host summary Alex Halpern summarizing a resource: There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis. Open

Quick Literature Updates Episode 16

Host summary Alex Halpern summarizing a resource: The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay. Open
Host summary Alex Halpern summarizing a resource: Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake. Open
Host summary Alex Halpern summarizing a resource: So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis. Open

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Host summary Alex Halpern summarizing a resource: A retrospective review by Men et al examined all patients who underwent conservative management of modified Bell stage 2A or greater NEC at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of NEC in the study period. Open
Host summary Alex Halpern summarizing a resource: 24 of 126 patients (19%) who underwent conservative management of NEC eventually required surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: So, it seems like post neck strictures are a common occurrence after conservative management of neck. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of NEC. Open

Remote Ischemic Conditioning (RIC) Decreases the Incidence and Severity of Necrotizing Enterocolitis (NEC) - Validation in a Large Animal Model

Host summary Alex Halpern summarizing a resource: RIC has been shown to decrease rates of necrotizing enterocolitis in a rat model. Open
Host summary Alex Halpern summarizing a resource: Gadal used an established piglet NEC model to test RIC. Open
Host summary Alex Halpern summarizing a resource: Piglets were randomly assigned to receive RIC or serve as controls. Open
Host summary Alex Halpern summarizing a resource: RIC was initiated at 24 hours of life and consisted of 4 cycles of 4 minutes of arterial occlusion followed by reperfusion. Open
Host summary Alex Halpern summarizing a resource: Cycles were repeated every 24 hours in the low frequency group and every 12 hours in the high frequency group. Open
Host summary Alex Halpern summarizing a resource: 38 piglets were randomized into the control group, 26 into the low frequency group, and 22 into the high frequency group. Open
Host summary Alex Halpern summarizing a resource: High frequency RIC significantly reduced the incidence of NEC when compared to controls. Open
Host summary Alex Halpern summarizing a resource: Low frequency RIC did not significantly reduce the incidence of NEC. Open
Host summary Alex Halpern summarizing a resource: High frequency RIC protects against NEC in a piglet model. Open
Host summary Alex Halpern summarizing a resource: So it seems like high frequency Rick protects against neck in a piglet model. Open

Quick Literature Updates Ep 22

Host summary Alex Halpern summarizing a resource: The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis. Open
Host summary Alex Halpern summarizing a resource: For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants. Open

Quick Literature Updates Ep 27

Host summary Alex Halpern summarizing a resource: Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: So it seems like post-neck strictures are a common occurrence after conservative management of neck. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis. Open
Summaries Alex gave as host · Gastroschisis 22 summaries

Open the Gastroschisis collection →

Quick Literature Updates Episode 11

Host summary Alex Halpern summarizing a resource: Pain control after appendectomy for perforated appendicitis can be a huge problem in kids. Open
Host summary Alex Halpern summarizing a resource: Could Gabapentin help with pain control in these kids? Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use. Open
Host summary Alex Halpern summarizing a resource: Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019. Open
Host summary Alex Halpern summarizing a resource: Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery. Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Host summary Alex Halpern summarizing a resource: The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Delivery after 37 weeks is optimal for infants with gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe and effective. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients. Open
Host summary Alex Halpern summarizing a resource: There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis. Open

Quick Literature Updates Episode 16

Host summary Alex Halpern summarizing a resource: The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake. Open
Host summary Alex Halpern summarizing a resource: In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay. Open
Host summary Alex Halpern summarizing a resource: So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis. Open

Quick Literature Updates Ep 22

Host summary Alex Halpern summarizing a resource: The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis. Open
Host summary Alex Halpern summarizing a resource: For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants. Open
Summaries Alex gave as host · Giant Omphalocele 7 summaries

Open the Giant Omphalocele collection →

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Host summary Alex Halpern summarizing a resource: Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device. Open
Host summary Alex Halpern summarizing a resource: The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No patients developed abdominal compartment syndrome in the study. Open
Host summary Alex Halpern summarizing a resource: No ventral hernias occurred after a median follow-up of 12 months. Open
Host summary Alex Halpern summarizing a resource: Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects. Open
Summaries Alex gave as host · Hirschsprung disease 19 summaries

Open the Hirschsprung disease collection →

Quick Literature Updates Episode 17

Host summary Alex Halpern summarizing a resource: The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study included 679 patients from 14 different sites. Open
Host summary Alex Halpern summarizing a resource: Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. Open
Host summary Alex Halpern summarizing a resource: Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through. Open
Host summary Alex Halpern summarizing a resource: The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision. Open

Quick Literature Updates Ep 22

Host summary Alex Halpern summarizing a resource: The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis. Open
Host summary Alex Halpern summarizing a resource: For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay. Open
Host summary Alex Halpern summarizing a resource: The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants. Open

Quick Literature Updates Ep 23

Host summary Alex Halpern summarizing a resource: A working group of pediatric surgeons from Europe created 19 case scenarios with unexpected events to validate the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: Surgeons within the European Reference Network of inherited and congenital anomalies rated scenarios based on the Clavien-Dindo classification or the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: A total of 59 surgeons completed the questionnaire. Open
Host summary Alex Halpern summarizing a resource: The Clavian-Matti classification showed significantly better agreement rates and was less frequently considered inaccurate. Open
Host summary Alex Halpern summarizing a resource: The Clavien-Madadi classification showed significantly better agreement rates and was less frequently considered inaccurate compared to Clavien-Dindo. Open
Host summary Alex Halpern summarizing a resource: More pediatric surgeons preferred using the Clavien-Madadi classification. Open
Host summary Alex Halpern summarizing a resource: The Clavien-Madadi classification is both an accurate and useful tool in grading unexpected events in pediatric surgery. Open
Host summary Alex Halpern summarizing a resource: So it seems like the Clavian-Matti classification is both an accurate and useful tool in grading unexpected events in pediatric surgery. Open
Summaries Alex gave as host · Intestinal Rehab 57 summaries

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Quick Literature Updates Episode 11

Host summary Alex Halpern summarizing a resource: Could Gabapentin help with pain control in these kids? Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay. Open
Host summary Alex Halpern summarizing a resource: Pain control after appendectomy for perforated appendicitis can be a huge problem in kids. Open
Host summary Alex Halpern summarizing a resource: Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery. Open
Host summary Alex Halpern summarizing a resource: Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019. Open
Host summary Alex Halpern summarizing a resource: In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use. Open

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Host summary Alex Halpern summarizing a resource: McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis. Open

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Host summary Alex Halpern summarizing a resource: Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device. Open
Host summary Alex Halpern summarizing a resource: The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele. Open
Host summary Alex Halpern summarizing a resource: Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No ventral hernias occurred after a median follow-up of 12 months. Open
Host summary Alex Halpern summarizing a resource: No patients developed abdominal compartment syndrome in the study. Open
Host summary Alex Halpern summarizing a resource: Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects. Open

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Host summary Alex Halpern summarizing a resource: The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Delivery after 37 weeks is optimal for infants with gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe and effective. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients. Open
Host summary Alex Halpern summarizing a resource: There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis. Open

Quick Literature Updates Episode 16

Host summary Alex Halpern summarizing a resource: The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay. Open
Host summary Alex Halpern summarizing a resource: Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake. Open
Host summary Alex Halpern summarizing a resource: So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis. Open

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Host summary Alex Halpern summarizing a resource: A retrospective review by Men et al examined all patients who underwent conservative management of modified Bell stage 2A or greater NEC at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of NEC in the study period. Open
Host summary Alex Halpern summarizing a resource: 24 of 126 patients (19%) who underwent conservative management of NEC eventually required surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of NEC. Open
Host summary Alex Halpern summarizing a resource: So, it seems like post neck strictures are a common occurrence after conservative management of neck. Open

Remote Ischemic Conditioning (RIC) Decreases the Incidence and Severity of Necrotizing Enterocolitis (NEC) - Validation in a Large Animal Model

Host summary Alex Halpern summarizing a resource: RIC has been shown to decrease rates of necrotizing enterocolitis in a rat model. Open
Host summary Alex Halpern summarizing a resource: Gadal used an established piglet NEC model to test RIC. Open
Host summary Alex Halpern summarizing a resource: Piglets were randomly assigned to receive RIC or serve as controls. Open
Host summary Alex Halpern summarizing a resource: RIC was initiated at 24 hours of life and consisted of 4 cycles of 4 minutes of arterial occlusion followed by reperfusion. Open
Host summary Alex Halpern summarizing a resource: Cycles were repeated every 24 hours in the low frequency group and every 12 hours in the high frequency group. Open
Host summary Alex Halpern summarizing a resource: 38 piglets were randomized into the control group, 26 into the low frequency group, and 22 into the high frequency group. Open
Host summary Alex Halpern summarizing a resource: High frequency RIC significantly reduced the incidence of NEC when compared to controls. Open
Host summary Alex Halpern summarizing a resource: Low frequency RIC did not significantly reduce the incidence of NEC. Open
Host summary Alex Halpern summarizing a resource: So it seems like high frequency Rick protects against neck in a piglet model. Open
Host summary Alex Halpern summarizing a resource: High frequency RIC protects against NEC in a piglet model. Open

Quick Literature Updates Ep 22

Host summary Alex Halpern summarizing a resource: The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis. Open
Host summary Alex Halpern summarizing a resource: For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure. Open
Host summary Alex Halpern summarizing a resource: Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay. Open
Host summary Alex Halpern summarizing a resource: Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit. Open
Host summary Alex Halpern summarizing a resource: The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants. Open

Quick Literature Updates Ep 27

Host summary Alex Halpern summarizing a resource: Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: So it seems like post-neck strictures are a common occurrence after conservative management of neck. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis. Open
Summaries Alex gave as host · Necrotizing Enterocolitis 23 summaries

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Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Host summary Alex Halpern summarizing a resource: McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis. Open
Host summary Alex Halpern summarizing a resource: Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis. Open

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Host summary Alex Halpern summarizing a resource: A retrospective review by Men et al examined all patients who underwent conservative management of modified Bell stage 2A or greater NEC at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of NEC in the study period. Open
Host summary Alex Halpern summarizing a resource: 24 of 126 patients (19%) who underwent conservative management of NEC eventually required surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of NEC. Open
Host summary Alex Halpern summarizing a resource: So, it seems like post neck strictures are a common occurrence after conservative management of neck. Open

Remote Ischemic Conditioning (RIC) Decreases the Incidence and Severity of Necrotizing Enterocolitis (NEC) - Validation in a Large Animal Model

Host summary Alex Halpern summarizing a resource: RIC has been shown to decrease rates of necrotizing enterocolitis in a rat model. Open
Host summary Alex Halpern summarizing a resource: Gadal used an established piglet NEC model to test RIC. Open
Host summary Alex Halpern summarizing a resource: Piglets were randomly assigned to receive RIC or serve as controls. Open
Host summary Alex Halpern summarizing a resource: RIC was initiated at 24 hours of life and consisted of 4 cycles of 4 minutes of arterial occlusion followed by reperfusion. Open
Host summary Alex Halpern summarizing a resource: Cycles were repeated every 24 hours in the low frequency group and every 12 hours in the high frequency group. Open
Host summary Alex Halpern summarizing a resource: 38 piglets were randomized into the control group, 26 into the low frequency group, and 22 into the high frequency group. Open
Host summary Alex Halpern summarizing a resource: High frequency RIC significantly reduced the incidence of NEC when compared to controls. Open
Host summary Alex Halpern summarizing a resource: Low frequency RIC did not significantly reduce the incidence of NEC. Open
Host summary Alex Halpern summarizing a resource: High frequency RIC protects against NEC in a piglet model. Open
Host summary Alex Halpern summarizing a resource: So it seems like high frequency Rick protects against neck in a piglet model. Open
Summaries Alex gave as host · Non-perforated Appendicitis 6 summaries

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Quick Literature Updates Ep 26

Host summary Alex Halpern summarizing a resource: Zoo et al. used the PHIS database and performed a multi-institutional cohort study of all ARM patients between 2016 and 2022 Open
Host summary Alex Halpern summarizing a resource: In ARM patients, the rates of actual diagnoses across all hospital encounters were 45.4% vertebral spinal, 77.4% cardiac, 10.2% TEF, 39.9% renal and 15.7% limb Open
Host summary Alex Halpern summarizing a resource: 25.8% of female patients with anorectal malformations had a congenital gynecologic malformation diagnosed Open
Host summary Alex Halpern summarizing a resource: So it seems like the most common anomalies associated with ARMs are cardiac, vertebrospinal, renal, and gynecologic. Open
Host summary Alex Halpern summarizing a resource: The most common anomalies associated with ARMs are cardiac, vertebrospinal, renal, and gynecologic Open
Host summary Alex Halpern summarizing a resource: The authors of the ARM screening study suggest changing the VACTERL acronym to VACTERL-GS Open
Summaries Alex gave as host · Pectus Excavatum 4 summaries

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Quick Literature Updates Episode 13

Host summary Alex Halpern summarizing a resource: Early initiation of peritoneal dialysis was associated with decreased post-operative mortality in infants after pediatric cardiac surgery. Open
Host summary Alex Halpern summarizing a resource: Early initiation of peritoneal dialysis shortened length of stay in the ICU in infants after pediatric cardiac surgery. Open
Host summary Alex Halpern summarizing a resource: Early initiation of peritoneal dialysis shortened duration of mechanical ventilation in infants after pediatric cardiac surgery. Open
Host summary Alex Halpern summarizing a resource: So it seems that early initiation of peritoneal dialysis may benefit infants after pediatric cardiac surgery. Open
Summaries Alex gave as host · Peritoneal Dialysis Access 4 summaries

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Quick Literature Updates Episode 13

Host summary Alex Halpern summarizing a resource: Early initiation of peritoneal dialysis was associated with decreased post-operative mortality in infants after pediatric cardiac surgery. Open
Host summary Alex Halpern summarizing a resource: Early initiation of peritoneal dialysis shortened duration of mechanical ventilation in infants after pediatric cardiac surgery. Open
Host summary Alex Halpern summarizing a resource: Early initiation of peritoneal dialysis shortened length of stay in the ICU in infants after pediatric cardiac surgery. Open
Host summary Alex Halpern summarizing a resource: So it seems that early initiation of peritoneal dialysis may benefit infants after pediatric cardiac surgery. Open
Summaries Alex gave as host · Tracheomalacia 5 summaries

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Quick Literature Updates Ep 27

Host summary Alex Halpern summarizing a resource: Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022. Open
Host summary Alex Halpern summarizing a resource: 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture. Open
Host summary Alex Halpern summarizing a resource: Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery. Open
Host summary Alex Halpern summarizing a resource: Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis. Open
Host summary Alex Halpern summarizing a resource: So it seems like post-neck strictures are a common occurrence after conservative management of neck. Open
Summaries Alex gave as host · Wilms Tumor 4 summaries

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Quick Literature Updates Ep 21

Host summary Alex Halpern summarizing a resource: Gillielli et al. reviewed 104 abstracts and 34 full text articles, ultimately including 12 studies in their systematic review of female fertility cryopreservation in childhood cancer. Open
Host summary Alex Halpern summarizing a resource: Ovarian tissue cryopreservation was performed in 501 pediatric cancer patients, with 5.9% undergoing ovarian tissue transplantation. Open
Host summary Alex Halpern summarizing a resource: After ovarian tissue transplantation, 33% of pediatric cancer patients were able to become pregnant. Open
Host summary Alex Halpern summarizing a resource: Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further. Open