Alex Halpern

555 timestamped statements across 23 collections — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Abdominal Wall Defects · guest expert Colorectal / ARM & Hirschsprung · guest expert Congenital Lung Lesions (CPAM) · guest expert Etiologies (Gastroschisis/NEC/Atresia/Volvulus) · guest expert Intestinal Rehab · guest expert Pancreatitis · episode host Pectus Excavatum · episode host Peritoneal Dialysis Access · guest expert Sarcoma (Ewing/Rhabdo) · episode host Wilms Tumor · guest expert

Featured diaries

Ep 134 · 0:41
They found that children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group, showing that standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery.
Ep 48 · 3:14
So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
Ep 149 · 3:14
So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
Ep 32 · 0:51
So it seems like both of these options have their pros and cons with the intercostal nerve co ablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
Ep 9 · 3:14
So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
quote · Trisomy 21
Ep 56 · 2:33
No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older.

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Quick Literature Updates Episode 11

Ep 32 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use.
Ep 32 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay.
Ep 32 · 2:11
host_summary Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery.
Ep 32 · 2:11
quote Pain control after appendectomy for perforated appendicitis can be a huge problem in kids.
Ep 32 · 2:11
quote Could Gabapentin help with pain control in these kids?
Ep 32 · 2:11
host_summary Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019.

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Ep 35 · 0:00
quote Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis?
Ep 35 · 0:13
host_summary McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes.
Ep 35 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis.
Ep 35 · 0:24
host_summary Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis.
Ep 35 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis.
Ep 35 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis.
Ep 35 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis.
Ep 35 · 0:44
host_summary Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis.
Ep 35 · 0:52
quote Does this information change your practice at all?

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Ep 38 · 0:14
host_summary Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device.
Ep 38 · 0:24
host_summary The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device.
Ep 38 · 0:29
host_summary Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele.
Ep 38 · 0:36
host_summary Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis.
Ep 38 · 0:39
host_summary No patients developed abdominal compartment syndrome in the study.
Ep 38 · 0:39
host_summary No ventral hernias occurred after a median follow-up of 12 months.
Ep 38 · 0:46
host_summary Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects.

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Ep 40 · 0:00
quote What is the optimal initial management of an infant with gastroschisis?
Ep 40 · 0:10
host_summary The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis.
Ep 40 · 0:17
host_summary Delivery after 37 weeks is optimal for infants with gastroschisis.
Ep 40 · 0:21
host_summary Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis.
Ep 40 · 0:27
host_summary Sutureless repair for gastroschisis is safe and effective.
Ep 40 · 0:27
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 40 · 0:37
host_summary Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients.
Ep 40 · 0:41
host_summary There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis.
Ep 40 · 0:50
quote Does this information change your practice at all?

Quick Literature Updates Episode 16

Ep 41 · 2:08
host_summary The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis.
Ep 41 · 2:17
host_summary Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake.
Ep 41 · 2:17
host_summary In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay.
Ep 41 · 2:38
quote So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis.

Quick Literature Updates Episode 20

Ep 43 · 1:58
host_summary Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric).
Ep 43 · 1:58
epidemiological Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric).
Ep 43 · 2:13
clinical Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device.
Ep 43 · 2:13
host_summary Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device.
Ep 43 · 2:13
clinical Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device.
Ep 43 · 2:13
host_summary Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device.
Ep 43 · 2:23
host_summary No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric.
Ep 43 · 2:23
host_summary No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric.
Ep 43 · 2:23
clinical No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric.
Ep 43 · 2:23
clinical No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric.
Ep 43 · 2:29
quote So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients.
Ep 43 · 2:29
quote So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients.

Quick Literature Updates Ep 22

Ep 44 · 2:11
host_summary The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis.
Ep 44 · 2:21
host_summary For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure.
Ep 44 · 2:28
host_summary Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay.
Ep 44 · 2:28
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 44 · 2:42
host_summary The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants.
Ep 44 · 2:51
quote Does this information change your practice at all?

Quick Literature Updates Episode 14

Ep 48 · 2:30
host_summary Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum.
Ep 48 · 2:40
quote Now, what are the benefits of each?
Ep 48 · 2:42
host_summary Dr. Tsai and his team from Penn State conducted a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020, comparing outcomes and costs of intercostal nerve cryoablation and epidural.
Ep 48 · 2:56
host_summary The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural.
Ep 48 · 2:56
host_summary The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural.
Ep 48 · 2:56
host_summary The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural.
Ep 48 · 3:07
host_summary The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural.
Ep 48 · 3:07
host_summary The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural.
Ep 48 · 3:14
quote So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
Ep 48 · 3:14
host_summary Both intercostal nerve cryoablation and thoracic epidural have pros and cons, with cryoablation showing decreased total opioid use and decreased length of stay but increased operating room times and increased total cost.

Transition From Pediatric to Adult Healthcare for Colorectal Conditions: A Systematic Review

Ep 52 · 0:00
clinical Patients with anorectal malformations and Hirschsprung's disease need transfer from pediatric to adult providers to manage their colorectal conditions
Ep 52 · 0:22
epidemiological A team from Melbourne, Australia performed a systematic review and meta-analysis on transition of care for these conditions
Ep 52 · 0:28
epidemiological Eight studies were found on the topic of transition care for anorectal malformations and Hirschsprung's disease
Ep 52 · 0:30
epidemiological Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion
Ep 52 · 0:30
guideline Studies agreed that transitional care should start early in adolescence
Ep 52 · 0:40
epidemiological No models of transition care were identified in the systematic review
Ep 52 · 0:43
opinion More work is needed to ensure children with anorectal malformations and Hirschsprung's disease continue to receive optimal care as they grow older
Ep 52 · 0:53
quote Does this information change your practice at all?

Quick Literature Updates Episode 18

Ep 56 · 2:15
host_summary A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions.
Ep 56 · 2:24
host_summary Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion.
Ep 56 · 2:24
host_summary Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence.
Ep 56 · 2:33
host_summary No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care.
Ep 56 · 2:33
quote No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older.

Quick Literature Updates Ep 23

Ep 64 · 2:01
host_summary A working group of pediatric surgeons from Europe created 19 case scenarios with unexpected events to validate the Clavien-Madadi classification.
Ep 64 · 2:10
host_summary Surgeons within the European Reference Network of inherited and congenital anomalies rated scenarios based on the Clavien-Dindo classification or the Clavien-Madadi classification.
Ep 64 · 2:23
host_summary A total of 59 surgeons completed the questionnaire.
Ep 64 · 2:27
host_summary The Clavien-Madadi classification showed significantly better agreement rates and was less frequently considered inaccurate compared to Clavien-Dindo.
Ep 64 · 2:27
quote The Clavian-Matti classification showed significantly better agreement rates and was less frequently considered inaccurate.
Ep 64 · 2:34
host_summary More pediatric surgeons preferred using the Clavien-Madadi classification.
Ep 64 · 2:38
host_summary The Clavien-Madadi classification is both an accurate and useful tool in grading unexpected events in pediatric surgery.
Ep 64 · 2:38
quote So it seems like the Clavian-Matti classification is both an accurate and useful tool in grading unexpected events in pediatric surgery.
Appendicitis 6 entries

Quick Literature Updates Episode 11

Ep 10 · 2:11
quote Could Gabapentin help with pain control in these kids?
Ep 10 · 2:11
quote Pain control after appendectomy for perforated appendicitis can be a huge problem in kids.
Ep 10 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay.
Ep 10 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use.
Ep 10 · 2:11
host_summary Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019.
Ep 10 · 2:11
host_summary Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery.

Multi-Institutional Analysis of Choledocholithiasis in Pediatric vs Adult Patients

Ep 3 · 0:00
quote Can a surgery first approach be used for the management of cholodocholithiasis in children?
Ep 3 · 0:11
epidemiological Dantes et al. performed a multi-center retrospective review of pediatric and adult patients treated for choledocholithiasis between 2018 and 2024
Ep 3 · 0:22
epidemiological 724 patients were included in the study
Ep 3 · 0:25
clinical Surgery first approach with upfront laparoscopic cholecystectomy with intraoperative cholangiogram was performed in 201 pediatric patients and 169 adult patients
Ep 3 · 0:35
clinical Laparoscopic common bile duct exploration was attempted in 84 children and 140 adults in the surgery first group
Ep 3 · 0:43
clinical Common bile duct exploration success was higher in pediatric than adult patients
Ep 3 · 0:43
clinical Complication rates were similar between pediatric and adult patients in the surgery first approach
Ep 3 · 0:49
opinion A surgery first approach can be a safe and effective tool for managing choledocholithiasis in pediatric patients
Ep 3 · 0:55
quote Does this information change your practice?

Standardized perioperative care reduces colorectal surgical site infection in children

Ep 134 · 0:00
epidemiological Surgical site infections are a major cause of perioperative morbidity in children undergoing colorectal surgery
Ep 134 · 0:00
quote Surgical site infections are a major cause of perioperative morbidity in children undergoing colorectal surgery.
Ep 134 · 0:20
clinical The Western Pediatric Surgery Research Consortium conducted a prospective cohort study on children undergoing colorectal surgery across 10 hospitals in the US
Ep 134 · 0:32
clinical The study utilized an 8-part perioperative care bundle
Ep 134 · 0:32
clinical Children were split into either a high or low compliance group based on adherence to the care bundle
Ep 134 · 0:41
clinical Children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group
Ep 134 · 0:41
quote They found that children in the high compliance group had a statistically significant decrease in rates of superficial surgical site infection when compared to children in the low compliance group, showing that standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery.
Ep 134 · 0:41
opinion Standardization of perioperative care may decrease morbidity and improve outcomes in colorectal surgery

Quick Literature Updates Episode 14

Ep 149 · 2:30
host_summary Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum.
Ep 149 · 2:30
clinical Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum.
Ep 149 · 2:40
quote Now, what are the benefits of each?
Ep 149 · 2:40
quote Now, what are the benefits of each?
Ep 149 · 2:42
host_summary Dr. Tsai and his team from Penn State conducted a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020, comparing outcomes and costs of intercostal nerve cryoablation and epidural.
Ep 149 · 2:42
epidemiological Dr. Tsai and his team from Penn State conducted a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020, comparing outcomes and costs of intercostal nerve cryoablation and epidural.
Ep 149 · 2:56
host_summary The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural.
Ep 149 · 2:56
clinical The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural.
Ep 149 · 2:56
clinical The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural.
Ep 149 · 2:56
clinical The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural.
Ep 149 · 2:56
host_summary The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural.
Ep 149 · 2:56
host_summary The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural.
Ep 149 · 3:07
host_summary The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural.
Ep 149 · 3:07
clinical The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural.
Ep 149 · 3:07
clinical The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural.
Ep 149 · 3:07
host_summary The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural.
Ep 149 · 3:14
host_summary Both intercostal nerve cryoablation and thoracic epidural have pros and cons, with cryoablation showing decreased total opioid use and decreased length of stay but increased operating room times and increased total cost.
Ep 149 · 3:14
quote So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
Ep 149 · 3:14
opinion Both intercostal nerve cryoablation and thoracic epidural have pros and cons, with cryoablation showing decreased total opioid use and decreased length of stay but increased operating room times and increased total cost.
Ep 149 · 3:14
quote So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.

Transition From Pediatric to Adult Healthcare for Colorectal Conditions: A Systematic Review

Ep 163 · 0:00
clinical Patients with anorectal malformations and Hirschsprung's disease need transfer from pediatric to adult providers to manage their colorectal conditions
Ep 163 · 0:22
epidemiological A team from Melbourne, Australia performed a systematic review and meta-analysis on transition of care for these conditions
Ep 163 · 0:28
epidemiological Eight studies were found on the topic of transition care for anorectal malformations and Hirschsprung's disease
Ep 163 · 0:30
epidemiological Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion
Ep 163 · 0:30
guideline Studies agreed that transitional care should start early in adolescence
Ep 163 · 0:40
epidemiological No models of transition care were identified in the systematic review
Ep 163 · 0:43
opinion More work is needed to ensure children with anorectal malformations and Hirschsprung's disease continue to receive optimal care as they grow older
Ep 163 · 0:53
quote Does this information change your practice at all?

Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Ep 165 · 0:00
quote Does delayed diagnosis of Hirschrung disease affect postoperative and functional outcomes?
Ep 165 · 0:12
clinical The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes.
Ep 165 · 0:23
epidemiological The study included 679 patients with Hirschsprung disease from 14 different sites.
Ep 165 · 0:29
clinical Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 165 · 0:39
clinical Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 165 · 0:49
clinical No association was found between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 165 · 0:49
clinical No association was found between age at diagnosis and need for pull-through revision.
Ep 165 · 0:58
clinical Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients.
Ep 165 · 1:04
quote Does this information change your practice at all?

Quick Literature Updates Episode 17

Ep 172 · 2:05
host_summary The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease.
Ep 172 · 2:05
clinical The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease.
Ep 172 · 2:16
clinical The Hirschsprung study included 679 patients from 14 different sites.
Ep 172 · 2:16
host_summary The Hirschsprung study included 679 patients from 14 different sites.
Ep 172 · 2:22
host_summary Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 172 · 2:22
clinical Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 172 · 2:32
clinical Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 172 · 2:32
host_summary Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 172 · 2:42
host_summary The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 172 · 2:42
host_summary The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision.
Ep 172 · 2:42
clinical The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision.
Ep 172 · 2:42
clinical The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 172 · 2:51
quote So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients.
Ep 172 · 2:51
opinion Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients.
Ep 172 · 2:51
opinion Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients.
Ep 172 · 2:51
quote So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients.

Quick Literature Updates Episode 18

Ep 174 · 2:15
epidemiological A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions.
Ep 174 · 2:24
clinical Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion.
Ep 174 · 2:24
guideline Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence.
Ep 174 · 2:33
quote No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older.
Ep 174 · 2:33
clinical No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care.

Quick Literature Updates Ep 22

Ep 184 · 2:11
host_summary The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis.
Ep 184 · 2:21
host_summary For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure.
Ep 184 · 2:28
host_summary Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay.
Ep 184 · 2:28
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 184 · 2:42
host_summary The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants.
Ep 184 · 2:51
quote Does this information change your practice at all?

Quick Literature Updates Ep 23

Ep 185 · 2:01
clinical A working group of pediatric surgeons from Europe created 19 case scenarios with unexpected events to validate the Clavien-Madadi classification.
Ep 185 · 2:10
clinical Surgeons within the European Reference Network of inherited and congenital anomalies rated scenarios based on the Clavien-Dindo classification or the Clavien-Madadi classification.
Ep 185 · 2:23
epidemiological A total of 59 surgeons completed the questionnaire.
Ep 185 · 2:27
clinical The Clavien-Madadi classification showed significantly better agreement rates and was less frequently considered inaccurate compared to Clavien-Dindo.
Ep 185 · 2:27
quote The Clavian-Matti classification showed significantly better agreement rates and was less frequently considered inaccurate.
Ep 185 · 2:34
clinical More pediatric surgeons preferred using the Clavien-Madadi classification.
Ep 185 · 2:38
quote So it seems like the Clavian-Matti classification is both an accurate and useful tool in grading unexpected events in pediatric surgery.
Ep 185 · 2:38
opinion The Clavien-Madadi classification is both an accurate and useful tool in grading unexpected events in pediatric surgery.

Quick Literature Updates Ep 26

Ep 188 · 2:16
clinical Zoo et al. used the PHIS database and performed a multi-institutional cohort study of all ARM patients between 2016 and 2022
Ep 188 · 2:25
epidemiological In ARM patients, the rates of actual diagnoses across all hospital encounters were 45.4% vertebral spinal, 77.4% cardiac, 10.2% TEF, 39.9% renal and 15.7% limb
Ep 188 · 2:40
epidemiological 25.8% of female patients with anorectal malformations had a congenital gynecologic malformation diagnosed
Ep 188 · 2:45
clinical The most common anomalies associated with ARMs are cardiac, vertebrospinal, renal, and gynecologic
Ep 188 · 2:45
quote So it seems like the most common anomalies associated with ARMs are cardiac, vertebrospinal, renal, and gynecologic.
Ep 188 · 2:53
opinion The authors of the ARM screening study suggest changing the VACTERL acronym to VACTERL-GS

Quick Literature Updates Episode 20

Ep 12 · 1:58
host_summary Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric).
Ep 12 · 2:13
host_summary Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device.
Ep 12 · 2:13
host_summary Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device.
Ep 12 · 2:23
host_summary No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric.
Ep 12 · 2:23
host_summary No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric.
Ep 12 · 2:29
quote So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients.

Quick Literature Updates Episode 18

Ep 32 · 2:15
host_summary A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions.
Ep 32 · 2:15
epidemiological A systematic review found 8 studies examining transition from pediatric to adult healthcare for colorectal conditions.
Ep 32 · 2:24
host_summary Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence.
Ep 32 · 2:24
guideline Studies on transition care for colorectal conditions agreed that transitional care should start early in adolescence.
Ep 32 · 2:24
host_summary Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion.
Ep 32 · 2:24
clinical Studies found little evidence that transfer from pediatric to adult care for colorectal conditions is happening in a coordinated or timely fashion.
Ep 32 · 2:33
clinical No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care.
Ep 32 · 2:33
quote No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older.
Ep 32 · 2:33
host_summary No models of transition care were identified for children with anorectal malformations and Hirschsprung disease transitioning to adult care.
Ep 32 · 2:33
quote No models of transition care were identified, so it seems like more work is needed to ensure that these children with anorectal malformations and Hirschbung's disease continue to receive optimal care as they grow older.

Quick Literature Updates Episode 18

Ep 9 · 2:21
epidemiological Eight studies were found examining transition from pediatric to adult healthcare for colorectal conditions
Ep 9 · 2:24
epidemiological Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion
Ep 9 · 2:24
guideline Studies agreed that transitional care should start early in adolescence
Ep 9 · 2:33
epidemiological No models of transition care were identified for patients with anorectal malformations and Hirschsprung's disease
Constipation 9 entries

Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Ep 6 · 0:00
quote Does delayed diagnosis of Hirschrung disease affect postoperative and functional outcomes?
Ep 6 · 0:12
clinical The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes.
Ep 6 · 0:23
epidemiological The study included 679 patients with Hirschsprung disease from 14 different sites.
Ep 6 · 0:29
clinical Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 6 · 0:39
clinical Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 6 · 0:49
clinical No association was found between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 6 · 0:49
clinical No association was found between age at diagnosis and need for pull-through revision.
Ep 6 · 0:58
clinical Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients.
Ep 6 · 1:04
quote Does this information change your practice at all?
Esophageal Atresia 13 entries

Quick Literature Updates Episode 17

Ep 19 · 2:05
host_summary The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease.
Ep 19 · 2:16
host_summary The Hirschsprung study included 679 patients from 14 different sites.
Ep 19 · 2:22
host_summary Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 19 · 2:32
host_summary Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 19 · 2:42
host_summary The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision.
Ep 19 · 2:42
host_summary The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 19 · 2:51
opinion Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients.
Ep 19 · 2:51
quote So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients.

Quick Literature Updates Ep 27

Ep 26 · 2:05
host_summary Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022.
Ep 26 · 2:20
host_summary 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture.
Ep 26 · 2:29
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 26 · 2:33
host_summary Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis.
Ep 26 · 2:33
quote So it seems like post-neck strictures are a common occurrence after conservative management of neck.

Quick Literature Updates Episode 11

Ep 52 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use.
Ep 52 · 2:11
host_summary Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery.
Ep 52 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay.
Ep 52 · 2:11
host_summary Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019.
Ep 52 · 2:11
quote Could Gabapentin help with pain control in these kids?
Ep 52 · 2:11
quote Pain control after appendectomy for perforated appendicitis can be a huge problem in kids.

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Ep 55 · 0:00
quote Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis?
Ep 55 · 0:13
host_summary McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes.
Ep 55 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis.
Ep 55 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis.
Ep 55 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis.
Ep 55 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis.
Ep 55 · 0:24
host_summary Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis.
Ep 55 · 0:44
host_summary Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis.
Ep 55 · 0:52
quote Does this information change your practice at all?

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Ep 58 · 0:14
host_summary Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device.
Ep 58 · 0:24
host_summary The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device.
Ep 58 · 0:29
host_summary Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele.
Ep 58 · 0:36
host_summary Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis.
Ep 58 · 0:39
host_summary No patients developed abdominal compartment syndrome in the study.
Ep 58 · 0:39
host_summary No ventral hernias occurred after a median follow-up of 12 months.
Ep 58 · 0:46
host_summary Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects.

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Ep 60 · 0:00
quote What is the optimal initial management of an infant with gastroschisis?
Ep 60 · 0:10
host_summary The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis.
Ep 60 · 0:17
host_summary Delivery after 37 weeks is optimal for infants with gastroschisis.
Ep 60 · 0:21
host_summary Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis.
Ep 60 · 0:27
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 60 · 0:27
host_summary Sutureless repair for gastroschisis is safe and effective.
Ep 60 · 0:37
host_summary Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients.
Ep 60 · 0:41
host_summary There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis.
Ep 60 · 0:50
quote Does this information change your practice at all?

Quick Literature Updates Episode 16

Ep 61 · 2:08
host_summary The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis.
Ep 61 · 2:17
host_summary In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay.
Ep 61 · 2:17
host_summary Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake.
Ep 61 · 2:38
quote So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis.

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Ep 62 · 0:00
quote How big of a problem are intestinal strictures after conservative management of necrotizing enterocolitis?
Ep 62 · 0:13
host_summary A retrospective review by Men et al examined all patients who underwent conservative management of modified Bell stage 2A or greater NEC at a single institution from 2011 to 2022.
Ep 62 · 0:27
host_summary 126 patients underwent conservative management of NEC in the study period.
Ep 62 · 0:27
host_summary 24 of 126 patients (19%) who underwent conservative management of NEC eventually required surgery for a post-NEC stricture.
Ep 62 · 0:36
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 62 · 0:40
host_summary Post-NEC strictures are a common occurrence after conservative management of NEC.
Ep 62 · 0:40
quote So, it seems like post neck strictures are a common occurrence after conservative management of neck.
Ep 62 · 0:46
quote Does this information change your practice at all?

Remote Ischemic Conditioning (RIC) Decreases the Incidence and Severity of Necrotizing Enterocolitis (NEC) - Validation in a Large Animal Model

Ep 64 · 0:00
host_summary RIC has been shown to decrease rates of necrotizing enterocolitis in a rat model.
Ep 64 · 0:16
host_summary Gadal used an established piglet NEC model to test RIC.
Ep 64 · 0:20
host_summary Piglets were randomly assigned to receive RIC or serve as controls.
Ep 64 · 0:24
host_summary RIC was initiated at 24 hours of life and consisted of 4 cycles of 4 minutes of arterial occlusion followed by reperfusion.
Ep 64 · 0:31
host_summary Cycles were repeated every 24 hours in the low frequency group and every 12 hours in the high frequency group.
Ep 64 · 0:37
host_summary 38 piglets were randomized into the control group, 26 into the low frequency group, and 22 into the high frequency group.
Ep 64 · 0:45
host_summary High frequency RIC significantly reduced the incidence of NEC when compared to controls.
Ep 64 · 0:50
host_summary Low frequency RIC did not significantly reduce the incidence of NEC.
Ep 64 · 0:53
quote So it seems like high frequency Rick protects against neck in a piglet model.
Ep 64 · 0:53
host_summary High frequency RIC protects against NEC in a piglet model.

Quick Literature Updates Ep 22

Ep 68 · 2:11
host_summary The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis.
Ep 68 · 2:21
host_summary For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure.
Ep 68 · 2:28
host_summary Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay.
Ep 68 · 2:28
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 68 · 2:42
host_summary The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants.
Ep 68 · 2:51
quote Does this information change your practice at all?

Quick Literature Updates Ep 27

Ep 69 · 2:05
host_summary Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022.
Ep 69 · 2:20
host_summary 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture.
Ep 69 · 2:29
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 69 · 2:33
host_summary Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis.
Ep 69 · 2:33
quote So it seems like post-neck strictures are a common occurrence after conservative management of neck.
Gastroschisis 25 entries

Quick Literature Updates Episode 11

Ep 20 · 2:11
host_summary Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery.
Ep 20 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use.
Ep 20 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay.
Ep 20 · 2:11
quote Pain control after appendectomy for perforated appendicitis can be a huge problem in kids.
Ep 20 · 2:11
quote Could Gabapentin help with pain control in these kids?
Ep 20 · 2:11
host_summary Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019.

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Ep 24 · 0:00
quote What is the optimal initial management of an infant with gastroschisis?
Ep 24 · 0:10
host_summary The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis.
Ep 24 · 0:17
host_summary Delivery after 37 weeks is optimal for infants with gastroschisis.
Ep 24 · 0:21
host_summary Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis.
Ep 24 · 0:27
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 24 · 0:27
host_summary Sutureless repair for gastroschisis is safe and effective.
Ep 24 · 0:37
host_summary Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients.
Ep 24 · 0:41
host_summary There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis.
Ep 24 · 0:50
quote Does this information change your practice at all?

Quick Literature Updates Episode 16

Ep 25 · 2:08
host_summary The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis.
Ep 25 · 2:17
host_summary Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake.
Ep 25 · 2:17
host_summary In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay.
Ep 25 · 2:38
quote So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis.

Quick Literature Updates Ep 22

Ep 27 · 2:11
host_summary The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis.
Ep 27 · 2:21
host_summary For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure.
Ep 27 · 2:28
host_summary Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay.
Ep 27 · 2:28
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 27 · 2:42
host_summary The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants.
Ep 27 · 2:51
quote Does this information change your practice at all?
Giant Omphalocele 13 entries

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Ep 5 · 0:14
host_summary Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device.
Ep 5 · 0:24
host_summary The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device.
Ep 5 · 0:29
host_summary Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele.
Ep 5 · 0:36
host_summary Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis.
Ep 5 · 0:39
host_summary No ventral hernias occurred after a median follow-up of 12 months.
Ep 5 · 0:39
host_summary No patients developed abdominal compartment syndrome in the study.
Ep 5 · 0:46
host_summary Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects.

Quick Literature Updates Episode 20

Ep 6 · 1:58
epidemiological Ziegler et al. prospective study included 10 patients with giant omphalocele and 6 with complicated gastroschisis using a traction-assisted abdominal wall closure device (Fascia Tense Pediatric).
Ep 6 · 2:13
clinical Complete fascial closure was achieved after a median of 5 days in children with complicated gastroschisis using the Fascia Tense Pediatric device.
Ep 6 · 2:13
clinical Complete fascial closure was achieved after a median of 7 days in children with giant omphalocele using the Fascia Tense Pediatric device.
Ep 6 · 2:23
clinical No ventral hernias occurred after a median follow-up of 12 months in patients who underwent traction-assisted closure with Fascia Tense Pediatric.
Ep 6 · 2:23
clinical No patients developed abdominal compartment syndrome after traction-assisted closure with Fascia Tense Pediatric.
Ep 6 · 2:29
quote So it seems like fascia tense pediatric helps facilitate early fascial closure in these patients.

Transition From Pediatric to Adult Healthcare for Colorectal Conditions: A Systematic Review

Ep 70 · 0:00
clinical Patients with anorectal malformations and Hirschsprung's disease need transfer from pediatric to adult providers to manage their colorectal conditions
Ep 70 · 0:22
epidemiological A team from Melbourne, Australia performed a systematic review and meta-analysis on transition of care for these conditions
Ep 70 · 0:28
epidemiological Eight studies were found on the topic of transition care for anorectal malformations and Hirschsprung's disease
Ep 70 · 0:30
epidemiological Little evidence exists that transfer from pediatric to adult care is happening in a coordinated or timely fashion
Ep 70 · 0:30
guideline Studies agreed that transitional care should start early in adolescence
Ep 70 · 0:40
epidemiological No models of transition care were identified in the systematic review
Ep 70 · 0:43
opinion More work is needed to ensure children with anorectal malformations and Hirschsprung's disease continue to receive optimal care as they grow older
Ep 70 · 0:53
quote Does this information change your practice at all?

Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Ep 72 · 0:00
quote Does delayed diagnosis of Hirschrung disease affect postoperative and functional outcomes?
Ep 72 · 0:12
clinical The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes.
Ep 72 · 0:23
epidemiological The study included 679 patients with Hirschsprung disease from 14 different sites.
Ep 72 · 0:29
clinical Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 72 · 0:39
clinical Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 72 · 0:49
clinical No association was found between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 72 · 0:49
clinical No association was found between age at diagnosis and need for pull-through revision.
Ep 72 · 0:58
clinical Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients.
Ep 72 · 1:04
quote Does this information change your practice at all?

Quick Literature Updates Episode 17

Ep 75 · 2:05
host_summary The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease.
Ep 75 · 2:05
clinical The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining delayed diagnosis of Hirschsprung disease.
Ep 75 · 2:16
host_summary The Hirschsprung study included 679 patients from 14 different sites.
Ep 75 · 2:16
clinical The Hirschsprung study included 679 patients from 14 different sites.
Ep 75 · 2:22
host_summary Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 75 · 2:22
clinical Increased age at diagnosis of Hirschsprung disease was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure.
Ep 75 · 2:32
clinical Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 75 · 2:32
host_summary Increasing age at diagnosis of Hirschsprung disease was associated with an increased risk of constipation or incontinence requiring intervention postoperatively.
Ep 75 · 2:42
clinical The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 75 · 2:42
clinical The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision.
Ep 75 · 2:42
host_summary The Hirschsprung study did not find an association between age at diagnosis and 30-day complication rate after initial pull-through.
Ep 75 · 2:42
host_summary The Hirschsprung study did not find an association between age at diagnosis and need for pull-through revision.
Ep 75 · 2:51
opinion Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients.
Ep 75 · 2:51
quote So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients.
Ep 75 · 2:51
opinion Delayed diagnosis of Hirschsprung disease does affect certain outcomes in these patients.
Ep 75 · 2:51
quote So, it seems like delayed diagnosis of Hirschrung's disease does affect certain outcomes in these patients.

Quick Literature Updates Ep 22

Ep 79 · 2:11
host_summary The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis.
Ep 79 · 2:21
host_summary For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure.
Ep 79 · 2:28
host_summary Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay.
Ep 79 · 2:28
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 79 · 2:42
host_summary The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants.
Ep 79 · 2:51
quote Does this information change your practice at all?

Quick Literature Updates Ep 23

Ep 80 · 2:01
clinical A working group of pediatric surgeons from Europe created 19 case scenarios with unexpected events to validate the Clavien-Madadi classification.
Ep 80 · 2:10
clinical Surgeons within the European Reference Network of inherited and congenital anomalies rated scenarios based on the Clavien-Dindo classification or the Clavien-Madadi classification.
Ep 80 · 2:23
epidemiological A total of 59 surgeons completed the questionnaire.
Ep 80 · 2:27
clinical The Clavien-Madadi classification showed significantly better agreement rates and was less frequently considered inaccurate compared to Clavien-Dindo.
Ep 80 · 2:27
quote The Clavian-Matti classification showed significantly better agreement rates and was less frequently considered inaccurate.
Ep 80 · 2:34
clinical More pediatric surgeons preferred using the Clavien-Madadi classification.
Ep 80 · 2:38
opinion The Clavien-Madadi classification is both an accurate and useful tool in grading unexpected events in pediatric surgery.
Ep 80 · 2:38
quote So it seems like the Clavian-Matti classification is both an accurate and useful tool in grading unexpected events in pediatric surgery.
Intestinal Rehab 64 entries

Quick Literature Updates Episode 11

Ep 76 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative opioid use.
Ep 76 · 2:11
host_summary Gabapentin is an anticonvulsant often used off-label as part of multimodal pain control after major surgery.
Ep 76 · 2:11
host_summary In the Lascano et al. study, kids who received gabapentin had decreased postoperative length of stay.
Ep 76 · 2:11
host_summary Lascano et al. performed a retrospective cohort study at Children's Hospital of LA looking at kids age 2 to 18 who underwent appendectomy for perforated appendicitis between 2014 and 2019.
Ep 76 · 2:11
quote Pain control after appendectomy for perforated appendicitis can be a huge problem in kids.
Ep 76 · 2:11
quote Could Gabapentin help with pain control in these kids?

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Ep 84 · 0:00
quote Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis?
Ep 84 · 0:13
host_summary McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes.
Ep 84 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis.
Ep 84 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis.
Ep 84 · 0:24
host_summary Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis.
Ep 84 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis.
Ep 84 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis.
Ep 84 · 0:44
host_summary Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis.
Ep 84 · 0:52
quote Does this information change your practice at all?

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients

Ep 87 · 0:14
host_summary Ziegler et al. performed a prospective study in 10 patients with giant omphalocele and 6 with complicated gastroschisis evaluating a vertical traction device.
Ep 87 · 0:24
host_summary The study utilized Fascia Tenses Pediatric, a traction-assisted abdominal wall closure device.
Ep 87 · 0:29
host_summary Complete fascial closure was achieved after a median time of 7 days in children with giant omphalocele.
Ep 87 · 0:36
host_summary Complete fascial closure was achieved after a median time of 5 days in children with complicated gastroschisis.
Ep 87 · 0:39
host_summary No patients developed abdominal compartment syndrome in the study.
Ep 87 · 0:39
host_summary No ventral hernias occurred after a median follow-up of 12 months.
Ep 87 · 0:46
host_summary Fascia Tenses Pediatric helps facilitate early fascial closure in patients with congenital abdominal wall defects.

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations

Ep 90 · 0:00
quote What is the optimal initial management of an infant with gastroschisis?
Ep 90 · 0:10
host_summary The ABSA Outcomes and Evidence-based Practice Committee performed a systematic review on optimal initial management of gastroschisis.
Ep 90 · 0:17
host_summary Delivery after 37 weeks is optimal for infants with gastroschisis.
Ep 90 · 0:21
host_summary Prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure in gastroschisis.
Ep 90 · 0:27
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 90 · 0:27
host_summary Sutureless repair for gastroschisis is safe and effective.
Ep 90 · 0:37
host_summary Sutureless repair does not delay feeding or increase length of stay in gastroschisis patients.
Ep 90 · 0:41
host_summary There is a need for high quality randomized controlled trials to help provide evidence-based care for infants with gastroschisis.
Ep 90 · 0:50
quote Does this information change your practice at all?

Quick Literature Updates Episode 16

Ep 91 · 2:08
host_summary The McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis.
Ep 91 · 2:17
host_summary In uncomplicated gastroschisis, there were no significant differences between exclusive breast milk and formula groups in time to reach full enteral feeds, duration of parenteral nutrition, rates of necrotizing enterocolitis, and length of hospital stay.
Ep 91 · 2:17
host_summary Infants with uncomplicated gastroschisis who received exclusive breast milk had similar outcomes to those with supplemental or exclusive formula intake.
Ep 91 · 2:38
quote So it seems like formula intake versus exclusive breast milk intake does not really affect outcomes in uncomplicated gastroschisis.

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Ep 92 · 0:00
quote How big of a problem are intestinal strictures after conservative management of necrotizing enterocolitis?
Ep 92 · 0:13
host_summary A retrospective review by Men et al examined all patients who underwent conservative management of modified Bell stage 2A or greater NEC at a single institution from 2011 to 2022.
Ep 92 · 0:27
host_summary 126 patients underwent conservative management of NEC in the study period.
Ep 92 · 0:27
host_summary 24 of 126 patients (19%) who underwent conservative management of NEC eventually required surgery for a post-NEC stricture.
Ep 92 · 0:36
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 92 · 0:40
quote So, it seems like post neck strictures are a common occurrence after conservative management of neck.
Ep 92 · 0:40
host_summary Post-NEC strictures are a common occurrence after conservative management of NEC.
Ep 92 · 0:46
quote Does this information change your practice at all?

Remote Ischemic Conditioning (RIC) Decreases the Incidence and Severity of Necrotizing Enterocolitis (NEC) - Validation in a Large Animal Model

Ep 95 · 0:00
host_summary RIC has been shown to decrease rates of necrotizing enterocolitis in a rat model.
Ep 95 · 0:16
host_summary Gadal used an established piglet NEC model to test RIC.
Ep 95 · 0:20
host_summary Piglets were randomly assigned to receive RIC or serve as controls.
Ep 95 · 0:24
host_summary RIC was initiated at 24 hours of life and consisted of 4 cycles of 4 minutes of arterial occlusion followed by reperfusion.
Ep 95 · 0:31
host_summary Cycles were repeated every 24 hours in the low frequency group and every 12 hours in the high frequency group.
Ep 95 · 0:37
host_summary 38 piglets were randomized into the control group, 26 into the low frequency group, and 22 into the high frequency group.
Ep 95 · 0:45
host_summary High frequency RIC significantly reduced the incidence of NEC when compared to controls.
Ep 95 · 0:50
host_summary Low frequency RIC did not significantly reduce the incidence of NEC.
Ep 95 · 0:53
host_summary High frequency RIC protects against NEC in a piglet model.
Ep 95 · 0:53
quote So it seems like high frequency Rick protects against neck in a piglet model.

Quick Literature Updates Ep 22

Ep 99 · 2:11
host_summary The APSA Outcomes and Evidence-based Practice Committee systematic review by Slidell et al. found that delivery after 37 weeks is optimal for gastroschisis.
Ep 99 · 2:21
host_summary For gastroschisis, prophylactic antibiotics covering skin flora are adequate to reduce infection risk until closure.
Ep 99 · 2:28
host_summary Sutureless repair for gastroschisis is safe, effective, and does not delay feeding or increase length of stay.
Ep 99 · 2:28
host_summary Studies support primary fascial repair for gastroschisis as long as hemodynamics and abdominal domain permit.
Ep 99 · 2:42
host_summary The APSA systematic review concluded that there is a need for high quality randomized controlled trials to help provide evidence-based care for gastroschisis infants.
Ep 99 · 2:51
quote Does this information change your practice at all?

Quick Literature Updates Ep 27

Ep 100 · 2:05
host_summary Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022.
Ep 100 · 2:20
host_summary 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture.
Ep 100 · 2:29
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 100 · 2:33
quote So it seems like post-neck strictures are a common occurrence after conservative management of neck.
Ep 100 · 2:33
host_summary Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis.

Association of Exclusive Breast Milk Intake and Outcomes in Infants With Uncomplicated Gastroschisis: A National Cohort Study

Ep 15 · 0:00
quote Does exclusive breast milk intake affect outcomes and uncomplicated gastroschisis?
Ep 15 · 0:13
host_summary McMaster University team performed a retrospective review of infants born between 2014 and 2022 with uncomplicated gastroschisis examining feeding outcomes.
Ep 15 · 0:24
host_summary Infants with exclusive breast milk intake and those with supplemental or exclusive formula intake had similar outcomes in uncomplicated gastroschisis.
Ep 15 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in duration of parenteral nutrition in infants with uncomplicated gastroschisis.
Ep 15 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in time to reach full enteral feeds in infants with uncomplicated gastroschisis.
Ep 15 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in rates of necrotizing enterocolitis in infants with uncomplicated gastroschisis.
Ep 15 · 0:24
host_summary No significant differences were found between exclusive breast milk and formula groups in length of hospital stay in infants with uncomplicated gastroschisis.
Ep 15 · 0:44
host_summary Formula intake versus exclusive breast milk intake does not appear to affect outcomes in uncomplicated gastroschisis.
Ep 15 · 0:52
quote Does this information change your practice at all?

Conservative Management of Necrotizing Enterocolitis in Newborns: Incidence and Management of Intestinal Strictures

Ep 16 · 0:00
quote How big of a problem are intestinal strictures after conservative management of necrotizing enterocolitis?
Ep 16 · 0:13
host_summary A retrospective review by Men et al examined all patients who underwent conservative management of modified Bell stage 2A or greater NEC at a single institution from 2011 to 2022.
Ep 16 · 0:27
host_summary 24 of 126 patients (19%) who underwent conservative management of NEC eventually required surgery for a post-NEC stricture.
Ep 16 · 0:27
host_summary 126 patients underwent conservative management of NEC in the study period.
Ep 16 · 0:36
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 16 · 0:40
quote So, it seems like post neck strictures are a common occurrence after conservative management of neck.
Ep 16 · 0:40
host_summary Post-NEC strictures are a common occurrence after conservative management of NEC.
Ep 16 · 0:46
quote Does this information change your practice at all?

Remote Ischemic Conditioning (RIC) Decreases the Incidence and Severity of Necrotizing Enterocolitis (NEC) - Validation in a Large Animal Model

Ep 18 · 0:00
host_summary RIC has been shown to decrease rates of necrotizing enterocolitis in a rat model.
Ep 18 · 0:16
host_summary Gadal used an established piglet NEC model to test RIC.
Ep 18 · 0:20
host_summary Piglets were randomly assigned to receive RIC or serve as controls.
Ep 18 · 0:24
host_summary RIC was initiated at 24 hours of life and consisted of 4 cycles of 4 minutes of arterial occlusion followed by reperfusion.
Ep 18 · 0:31
host_summary Cycles were repeated every 24 hours in the low frequency group and every 12 hours in the high frequency group.
Ep 18 · 0:37
host_summary 38 piglets were randomized into the control group, 26 into the low frequency group, and 22 into the high frequency group.
Ep 18 · 0:45
host_summary High frequency RIC significantly reduced the incidence of NEC when compared to controls.
Ep 18 · 0:50
host_summary Low frequency RIC did not significantly reduce the incidence of NEC.
Ep 18 · 0:53
quote So it seems like high frequency Rick protects against neck in a piglet model.
Ep 18 · 0:53
host_summary High frequency RIC protects against NEC in a piglet model.
Pancreatitis 9 entries

Multi-Institutional Analysis of Choledocholithiasis in Pediatric vs Adult Patients

Ep 22 · 0:00
quote Can a surgery first approach be used for the management of cholodocholithiasis in children?
Ep 22 · 0:11
epidemiological Dantes et al. performed a multi-center retrospective review of pediatric and adult patients treated for choledocholithiasis between 2018 and 2024
Ep 22 · 0:22
epidemiological 724 patients were included in the study
Ep 22 · 0:25
clinical Surgery first approach with upfront laparoscopic cholecystectomy with intraoperative cholangiogram was performed in 201 pediatric patients and 169 adult patients
Ep 22 · 0:35
clinical Laparoscopic common bile duct exploration was attempted in 84 children and 140 adults in the surgery first group
Ep 22 · 0:43
clinical Common bile duct exploration success was higher in pediatric than adult patients
Ep 22 · 0:43
clinical Complication rates were similar between pediatric and adult patients in the surgery first approach
Ep 22 · 0:49
opinion A surgery first approach can be a safe and effective tool for managing choledocholithiasis in pediatric patients
Ep 22 · 0:55
quote Does this information change your practice?
Pectus Excavatum 25 entries

Cost and outcomes of intercostal nerve cryoablation versus thoracic epidural following the Nuss procedure

Ep 32 · 0:00
quote Thoracic epidural and intercostal nerve coagabulations are two options for pain control in patients undergoing a NUS procedure for pectus excavatum.
Ep 32 · 0:00
clinical Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing a Nuss procedure for pectus excavatum
Ep 32 · 0:19
clinical Dr. Tsai and his team from Penn State conducted a retrospective chart review looking at kids who underwent a Nuss procedure between 2002 and 2020
Ep 32 · 0:21
clinical The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural
Ep 32 · 0:21
clinical The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural
Ep 32 · 0:21
clinical The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural
Ep 32 · 0:44
clinical The intercostal nerve cryoablation group had higher total hospitalization cost than the thoracic epidural group
Ep 32 · 0:44
clinical The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural
Ep 32 · 0:51
opinion Both intercostal nerve cryoablation and thoracic epidural have pros and cons for pain control following Nuss procedure
Ep 32 · 0:51
quote So it seems like both of these options have their pros and cons with the intercostal nerve co ablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.

Quick Literature Updates Episode 13

Ep 37 · 2:35
host_summary Early initiation of peritoneal dialysis was associated with decreased post-operative mortality in infants after pediatric cardiac surgery.
Ep 37 · 2:41
host_summary Early initiation of peritoneal dialysis shortened length of stay in the ICU in infants after pediatric cardiac surgery.
Ep 37 · 2:41
host_summary Early initiation of peritoneal dialysis shortened duration of mechanical ventilation in infants after pediatric cardiac surgery.
Ep 37 · 2:49
quote So it seems that early initiation of peritoneal dialysis may benefit infants after pediatric cardiac surgery.

Vacuum Bell Therapy for Pectus Excavatum: Long-term Experience at a Single Center

Ep 48 · 0:00
quote What factors affect outcomes in patients with pectus excavatum treated with vacuum valve therapy?
Ep 48 · 0:13
clinical The study was a single institution retrospective chart review conducted from 2012 to 2023
Ep 48 · 0:20
epidemiological 278 patients were included in the analysis
Ep 48 · 0:23
clinical 247 patients had non-excellent corrections with vacuum bell therapy
Ep 48 · 0:23
clinical 31 patients had excellent corrections with vacuum bell therapy
Ep 48 · 0:29
clinical Chest wall flexibility is a predictor of positive outcomes
Ep 48 · 0:29
clinical Initial chest depth less than 1.5 centimeters is a predictor of positive outcomes
Ep 48 · 0:29
clinical Excellent correction was more common in children 8 to 12.9 years old
Ep 48 · 0:41
opinion Excellent correction in children with pectus excavatum treated with vacuum bell therapy is uncommon
Ep 48 · 0:41
clinical Improved outcomes are seen in younger patients with more mild defects and greater chest wall flexibility
Ep 48 · 0:54
quote Does this information change your practice?

Early Peritoneal Dialysis and Postoperative Outcomes in Infants After Pediatric Cardiac Surgery

Ep 6 · 0:00
quote Can early initiation of peritoneal dialysis after pediatric cardiac surgery improve outcomes?
Ep 6 · 0:14
clinical Dr. Dudike and his team performed a systematic review and meta-analysis on early peritoneal dialysis after pediatric cardiac surgery
Ep 6 · 0:19
clinical Five studies were included in the meta-analysis
Ep 6 · 0:24
clinical Early initiation of peritoneal dialysis was associated with decreased postoperative mortality
Ep 6 · 0:30
clinical Early initiation of peritoneal dialysis shortened duration of mechanical ventilation
Ep 6 · 0:30
opinion Early initiation of peritoneal dialysis may benefit infants after pediatric cardiac surgery
Ep 6 · 0:30
clinical Early initiation of peritoneal dialysis shortened length of stay in the ICU

Quick Literature Updates Episode 13

Ep 7 · 2:35
host_summary Early initiation of peritoneal dialysis was associated with decreased post-operative mortality in infants after pediatric cardiac surgery.
Ep 7 · 2:41
host_summary Early initiation of peritoneal dialysis shortened length of stay in the ICU in infants after pediatric cardiac surgery.
Ep 7 · 2:41
host_summary Early initiation of peritoneal dialysis shortened duration of mechanical ventilation in infants after pediatric cardiac surgery.
Ep 7 · 2:49
quote So it seems that early initiation of peritoneal dialysis may benefit infants after pediatric cardiac surgery.

Female Fertility Cryopreservation Outcomes in Childhood Cancer: A Systematic Review

Ep 27 · 0:00
quote What does the current literature say about outcomes of female fertility cryopreservation in children with cancer?
Ep 27 · 0:13
clinical Gillippelli et al. performed a systematic retrospective review of female fertility cryopreservation outcomes in children with cancer
Ep 27 · 0:19
clinical 12 studies were included in the final systematic review
Ep 27 · 0:19
clinical The review initially examined 104 abstracts and 34 full text articles
Ep 27 · 0:27
epidemiological 5.9% of patients who underwent ovarian tissue cryopreservation later received ovarian tissue transplantation
Ep 27 · 0:27
epidemiological Ovarian tissue cryopreservation was performed in 501 patients across the included studies
Ep 27 · 0:38
clinical 33% of patients who underwent ovarian tissue transplantation were able to become pregnant
Ep 27 · 0:44
quote So, it seems like ovarian tissue cryopreservation has great advantages for pediatric cancer patients, but needs to be studied further.
Ep 27 · 0:44
opinion Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further
Ep 27 · 0:52
quote Does this information change your practice at all?

Same-Day Discharge for Elective Pediatric Laparoscopic Gastrostomy Tube Insertion is Safe and Increasing in Frequency; A NSQIP Pediatric Retrospective Review 2017 to 2021

Ep 29 · 0:00
quote What are the trends and outcomes of same-day discharge after pediatric elective laparoscopic gastrostomy?
Ep 29 · 0:13
clinical The study analyzed the ACS NSQIP Pediatric database from 2017 to 2021
Ep 29 · 0:21
epidemiological 5,947 pediatric patients underwent elective laparoscopic gastrostomy tube placement in the study period
Ep 29 · 0:29
epidemiological 4.7% of patients were discharged the same day after laparoscopic gastrostomy tube placement
Ep 29 · 0:33
clinical There were no significant differences in reoperations between same-day discharge and 1-2 day discharge patients
Ep 29 · 0:33
clinical There were no significant differences in any other complications between same-day discharge and 1-2 day discharge patients
Ep 29 · 0:33
clinical There were no significant differences in 30-day unplanned readmissions between same-day discharge and 1-2 day discharge patients
Ep 29 · 0:46
epidemiological Same-day discharge after pediatric laparoscopic gastrostomy is not commonly done
Ep 29 · 0:46
quote So, it seems like same day discharge for pediatric patients after elective laparoscopic gastrostomy is safe, but not commonly done.
Ep 29 · 0:46
opinion Same-day discharge for pediatric patients after elective laparoscopic gastrostomy appears to be safe
Tracheomalacia 5 entries

Quick Literature Updates Ep 27

Ep 7 · 2:05
host_summary Mina et al. performed a retrospective review of all patients who underwent conservative management of modified Bell stage 2A or greater necrotizing enterocolitis at a single institution from 2011 to 2022.
Ep 7 · 2:20
host_summary 126 patients underwent conservative management of necrotizing enterocolitis, and 24 of those patients eventually underwent surgery for a post-NEC stricture.
Ep 7 · 2:29
host_summary Primary resection and anastomosis was performed in all cases of post-NEC stricture requiring surgery.
Ep 7 · 2:33
host_summary Post-NEC strictures are a common occurrence after conservative management of necrotizing enterocolitis.
Ep 7 · 2:33
quote So it seems like post-neck strictures are a common occurrence after conservative management of neck.
Trisomy 21 8 entries

Quick Literature Updates Episode 14

Ep 9 · 2:30
clinical Thoracic epidural and intercostal nerve cryoablation are two options for pain control in patients undergoing Nuss procedure for pectus excavatum
Ep 9 · 2:42
epidemiological The study was a retrospective chart review of kids who underwent Nuss procedure between 2002 and 2020
Ep 9 · 2:56
clinical The intercostal nerve cryoablation group had shorter length of stay in the hospital compared to thoracic epidural
Ep 9 · 2:56
clinical The intercostal nerve cryoablation group had lower total morphine milligram equivalent requirement compared to thoracic epidural
Ep 9 · 2:56
clinical The intercostal nerve cryoablation group had lower rates of PCA use compared to thoracic epidural
Ep 9 · 3:07
clinical The intercostal nerve cryoablation group had higher total hospitalization cost compared to thoracic epidural
Ep 9 · 3:07
clinical The intercostal nerve cryoablation group had longer operative times compared to thoracic epidural
Ep 9 · 3:14
quote So it seems like both of these options have their pros and cons with the intercostal nerve carablation group having a decreased total opioid use and decreased length of stay in the hospital, but increased operating room times and increased total cost.
Wilms Tumor 10 entries

Quick Literature Updates Ep 21

Ep 16 · 2:04
host_summary Gillielli et al. reviewed 104 abstracts and 34 full text articles, ultimately including 12 studies in their systematic review of female fertility cryopreservation in childhood cancer.
Ep 16 · 2:04
epidemiological Gillielli et al. reviewed 104 abstracts and 34 full text articles, ultimately including 12 studies in their systematic review of female fertility cryopreservation in childhood cancer.
Ep 16 · 2:16
epidemiological Ovarian tissue cryopreservation was performed in 501 pediatric cancer patients, with 5.9% undergoing ovarian tissue transplantation.
Ep 16 · 2:16
host_summary Ovarian tissue cryopreservation was performed in 501 pediatric cancer patients, with 5.9% undergoing ovarian tissue transplantation.
Ep 16 · 2:27
host_summary After ovarian tissue transplantation, 33% of pediatric cancer patients were able to become pregnant.
Ep 16 · 2:27
clinical After ovarian tissue transplantation, 33% of pediatric cancer patients were able to become pregnant.
Ep 16 · 2:33
opinion Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further.
Ep 16 · 2:33
host_summary Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further.
Ep 16 · 2:41
quote Does this information change your practice at all?
Ep 16 · 2:41
quote Does this information change your practice at all?