Female Fertility Cryopreservation Outcomes in Childhood Cancer: A Systematic Review
Gillippelli et al. performed a systematic retrospective review of female fertility cryopreservation outcomes in children with cancer
The review initially examined 104 abstracts and 34 full text articles
12 studies were included in the final systematic review
Ovarian tissue cryopreservation was performed in 501 patients across the included studies
5.9% of patients who underwent ovarian tissue cryopreservation later received ovarian tissue transplantation
33% of patients who underwent ovarian tissue transplantation were able to become pregnant
Ovarian tissue cryopreservation has great advantages for pediatric cancer patients but needs to be studied further
Expert opinionAlex Halpern0:44
The systematic review aimed to highlight outcomes of cryopreservation in pediatric female patients with cancer
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:11
The review included 12 studies with 612 patients total
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:20
501 patients underwent ovarian tissue cryopreservation
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:26
Only 30 of the 501 patients received ovarian tissue transplantation
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:31
Of the 30 patients who received transplantation, 9 got pregnant
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:36
Only 6 of the 9 pregnancies resulted in live birth
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:40
More high quality studies are needed to understand cryopreservation better and improve its outcomes
Host summaryCecilia Gigena summarizing a resource — not the host's own clinical position0:43
ACS Icons in Surgery | Jeffrey L. Ponsky, MD, FACS
Basil Morrison in England was marking the tips of polyps with India ink to track polyp behavior over time.
Endoscopic marking of colonic lesions with India ink was developed in 1975 to enable surgeons to locate polypectomy sites when pathology revealed cancer.
India ink tattooing remains useful in the laparoscopic era when surgeons cannot palpate the colon to locate lesion sites.
The first endoscope cost $5,200 in 1974.
In the mid-1970s, endoscopes were cleaned with green soap before use.
Transillumination of the abdominal wall during pediatric endoscopy, where the endoscope light shone through the belly and finger indentation was visible, led to development of the PEG procedure.
Jacques Perrisat presented a video on laparoscopic cholecystectomy at a SAGES meeting in Louisville, Kentucky in 1989.
Dr. Jeff Ponsky's impact on surgical endoscopy has been foundational through academic advancement of technology and technique, mentorship, and leadership in professional organizations like ASGE and SAGES to bring gastroenterology and surgery together in endoscopy.
Host summaryThe host summarizes what Dr. Jeffrey L. Ponsky said — not the host's own clinical position11:19
The American Board of Surgery asked SAGES to nominate three members for a board director position representing minimally invasive surgery.
Ponsky contributed to the American Board of Surgery by developing educational components for minimally invasive surgery, creating examination questions, and establishing endoscopy training requirements for surgical residents.
Dr. Ponsky served as director and chair of the American Board of Surgery, president of both ASGE and SAGES, and vice president of the American Surgical Association and SSAT.
Host summaryThe host summarizes what Dr. Jeffrey L. Ponsky said — not the host's own clinical position14:36
Dr. Ponsky trained 35 endoscopic surgery fellows who now carry on his legacy.
Host summaryThe host summarizes what Dr. Jeffrey L. Ponsky said — not the host's own clinical position14:59
The endoscope should be conceptualized as a vehicle like a car or bus that transports surgeons to operative sites rather than primarily as a tool for mucosal inspection.
Expert opinionJeffrey L. Ponsky19:23
Surgeons use the endoscope as a vehicle to reach sites for operations including POEM, POP, Zenker's procedures, and NOTES.
Best of the Best Gen Surg - Limited Health Literacy is Associated with Reduced Adherence to ERP Components. - Dr. Shao
Health literacy is defined as the degree to which an individual has the capacity to obtain, communicate, process, and understand basic health information and services to make appropriate health decisions.
Cites a guidelineConnie Chow0:24
Health literacy is modifiable and health literacy-based interventions have been shown to improve outcomes and patient experience.