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A structured ERAS pathway meaningfully improves recovery even after complex neuroblastoma resections — Sophia Schermerhorn, Enhanced Recovery After Surgery (ERAS) Improves Length of Stay and Decreases Complications After Resection of Abdominal Neuroblastoma · 0:51
The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report
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Tom Monclair, Garrett M Brodeur, Peter F Ambros, Hervé J Brisse, Giovanni Cecchetto, Keith Holmes, Michio Kaneko, Wendy B London, Katherine K Matthay, Jed G Nuchtern, Dietrich von Schweinitz, Thorsten Simon, Susan L Cohn, Andrew D J Pearson
video0:59 · Mar 2026
Enhanced Recovery After Surgery (ERAS) Improves Length of Stay and Decreases Complications After Resection of Abdominal Neuroblastoma
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Sara A Mansfield, Meera Kotagal, Stephen J Hartman, Andrew J Murphy, Brady Hogan, Darren Ha, Doralina L Anghelescu, Marc Mecoli, Nicholas G Cost, Andrew M Davidoff, Kyle O RoveBackground: Enhanced recovery after surgery (ERAS) pathways are
video1:02 · Feb 2026
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Enhanced Recovery After Surgery (ERAS) Improves Length of Stay and Decreases Complications After Resection of Abdominal Neuroblastoma
A multi-center prospective study evaluated a structured ERAS pathway for children undergoing abdominal neuroblastoma resection
Sophia Schermerhorn0:03
The ERAS protocol included 20 evidence-based elements spanning the entire perioperative process
Sophia Schermerhorn0:13
ERAS protocol elements included preoperative counseling, hydrate loading, standardized multimodal analgesia, early feeding, and early mobilization
Sophia Schermerhorn0:13
Length of stay decreased from about 7 days to 3.7 days
Sophia Schermerhorn0:28
Post-operative opioid use dropped by over half
Sophia Schermerhorn0:32
Patients resumed regular diets and ambulated about 3 days earlier
Sophia Schermerhorn0:32
The proportion of patients experiencing any postoperative complication decreased by over 50%
Sophia Schermerhorn0:39
Patients were cleared to resume adjuvant chemotherapy earlier at around 8 days as opposed to 10 days
Sophia Schermerhorn0:46
A structured ERAS pathway meaningfully improves recovery even after complex neuroblastoma resections
ERAS represents a tangible opportunity to standardize perioperative care for neuroblastoma resection
The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report
IDRFs are necessary knowledge for clinicians treating neuroblastoma to determine safety of surgical intervention
Sophia Schermerhorn0:00
IDRFs are imaging findings on CT or MRI that predict when neuroblastoma may be difficult or dangerous to remove surgically
Sophia Schermerhorn0:14
The IDRF concept was first introduced in 2009 by the International Neuroblastoma Risk Group
The International Neuroblastoma Risk Group defined 20 specific imaging risk factors
Most IDRFs relate to how the tumor interacts with critical anatomy
Sophia Schermerhorn0:29
In the abdomen, a tumor that infiltrates the portahepati or hepatoduodenal ligament is considered to contain an IDRF
Sophia Schermerhorn0:34
The presence of an IDRF does not mean a tumor cannot be resected
Sophia Schermerhorn0:41
IDRF presence signals that surgery may be technically more complex
Sophia Schermerhorn0:41
Patients with IDRFs often receive neoadjuvant therapy first to try to shrink the tumor
Sophia Schermerhorn0:41
Surgeons use IDRFs to predict surgical risk and guide the safest treatment approach using imaging
Sophia Schermerhorn0:52