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Curated by Dr. Miguel Guelfand From 3 sources across the library

Abdominal Wall Defects: Omphalocele & Gastroschisis

items total cited expert statements Updated Oct 20, 2026
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The technique uses a 20 × 20 cm (8 × 8 inch) thick hydrocolloid dressing (Duoderm GRF) shaped into a T, with the stem attached to the skin and the flaps wrapped around the omphalocele. — Miguel Guelfand, EUPSA Webinar "GIANT OMPHALOCELE II" · 13:00

Giant Omphalocele2 items
Management of giant omphalocele with a simple and efficient nonsurgical silo
The staged silo management of giant omphalocele in this series is safe and effective and reduces the time to closure and potential morbidity and mortality compared with traditional surgical or medical management.
article · Jun 2026
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EUPSA Webinar "GIANT OMPHALOCELE II"
Marlinde van den Kamp (The Netherlands) Miguel Guelfand (USA) Moderated by Martin Lacher (Germany) Augusto Zani (Canada)
video1:04:07 · Jul 2026
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If the surgical technique for omphalocele closure involves exposing the intestines, it may be worth considering a Ladd procedure, but not worth going through the sac if the technique maintains the sac. Gastroschisis - Clinical Practice Updates · 10:31

Gastroschisis - Clinical Practice Updates
This clip from the 2020 Pediatric Surgery Update Course features, Miguel Guelfand, MD; Shawn St. Peter, MD; and Saleem Islam, MD; presenting challenging cases for review by our panelists. Highlighted Topics Include: - Omphalocele - Pul
video · Sep 2020
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Gastroschisis
This clip from the 2020 Pediatric Surgery Update Course features, Miguel Guelfand, MD; Shawn St. Peter, MD; and Saleem Islam, MD; presenting challenging cases for review by our panelists.Highlighted Topics Include:- Omphalocele- Pulmanary h
video · Jun 2026
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Complex gastroschisis is almost a different disease from simple variety; everything is worse including hospital length of stay, requirement for further operations, and sepsis rates Update Course Rewind: Omphalocele & Gastroschisis 2020 · 12:25

Update Course Rewind: Omphalocele & Gastroschisis 2020
Abdominal wall defects like omphalocele and gastroschisis can present in interesting ways. At last year
podcast15:18 · Jun 2026
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Gastroschisis - Clinical Practice Updates
Giant omphalocele (≥5 cm or liver in sac) patients had greater time to full feeds, required more TPN, had greater risk of respiratory insufficiency, and higher incidence of chromosomal anomalies compared to routine omphalocele in a two-center 20-year retrospective study of 97 survivors.
56 of 97 giant omphalocele patients were identified as having pulmonary hypertension, with most diagnosed within the first week of life.
Five patients with giant omphalocele had no signs of pulmonary hypertension on initial echo within first seven days but subsequently developed severe pulmonary hypertension after sepsis episodes, with two deaths and one requiring pulmonary vasodilator for more than a year.
One patient developed severe pulmonary hypertension 52 days after initial echo showed no pulmonary hypertension, triggered by a single episode of sepsis.
The sac-preserving active reduction technique developed by Dr. Abello from Colombia has been used in almost 40 patients over three years by Miguel Gilfoid's group.
Miguel Guelfand5:00
Using the sac-preserving technique with hydrocolloid dressing, 97% of patients achieved closure within 30 days and 92% within 15 days.
Miguel Guelfand5:00
All patients treated with the sac-preserving technique are kept in ICU, ventilated and completely paralyzed during the reduction process.
Miguel Guelfand5:00
The hydrocolloid dressing should ideally be applied within the first 24 hours after birth so the sac doesn't become very stiff, and it keeps the sac very smooth and hydrated.
Miguel Guelfand6:47
Three patients with ruptured omphalocele sac at birth were sutured and then had the hydrocolloid dressing applied successfully.
Miguel Guelfand6:47
Compressions can usually start within 48 hours after hydrocolloid application once the baby is stable.
Miguel Guelfand8:01
In a study by Amy Wegner comparing omphalocele and gastroschisis, gastroschisis had higher risk of adhesive bowel obstruction, but omphalocele had higher risk of midgut volvulus.
Patients with omphalocele have non-rotation or malrotation and will not have the same adhesions as gastroschisis patients.
If the surgical technique for omphalocele closure involves exposing the intestines, it may be worth considering a Ladd procedure, but not worth going through the sac if the technique maintains the sac.
Expert opinion10:31
During diaphragmatic hernia repair, the key move to decrease volvulus risk is to unroll the cecum and proximal bowel if they are rolled together like a scroll, ensuring small bowel is to the right, colon to the left, and anterior surface of mesentery is exposed.
Non-rotation does not exclude the possibility of having anatomy with a narrow base of mesentery and the two ends being fairly close together, creating volvulus risk.
In gastroschisis, the liver is not expected to be herniated outside the abdomen.
For massive abdominal wall defects where there is no amnion and nothing to sew, Miguel Gilfoid uses a prolene mesh that stays in place until closure can be achieved, protecting it with a plastic bag around the bowel.
Miguel Guelfand19:10
With giant abdominal wall defects, when a spring-loaded (tech) silo is placed and pushed down, the forces go outward and can actually make the defect much bigger over time.
Biologic mesh can be used as a scaffold that sticks to the bowel and allows skin to epithelialize over massive defects.
Miguel Gilfoid reports that 80% of massive gastroschisis cases can be closed within two to three months using prolene mesh that remains in place for months.
Miguel Guelfand23:21
Tissue expanders placed inside the belly without any domain would push all contents up and out rather than creating useful space, according to plastic surgery colleagues.
Host summaryThe host summarizing the discussion — not the host's own clinical position26:33
Component separation technique involves separating tissue at the external oblique about a centimeter beyond the rectus sheath bilaterally, then dissecting between external oblique and the transversus/internal oblique, which creates substantial room for closure.
An incision on top of the anterior rectus sheath can provide another centimeter of advancement during component separation.
A group from UT Houston (Cogen, Rich, and Recy) reported using component separation in nine children aged 7 days to 10 years, majority with omphalocele and giant defects, achieving fascial closure in almost every case, with some requiring mesh to bridge defects.
Host summaryThe host summarizing the discussion — not the host's own clinical position26:33
Update Course Rewind: Omphalocele & Gastroschisis 2020
Giant omphalocele is typically defined as five centimeters or greater or liver in the sac
In a two-center retrospective study encompassing 20 years with 97 survivors of giant omphalocele, patients had greater time to full feeds, required more TPN, had more chromosomal anomalies, and had higher incidence of respiratory insufficiency
56 patients of 97 giant omphalocele survivors were identified as having pulmonary hypertension, most diagnosed within the first week of life
Five patients out of 56 with pulmonary hypertension had no signs in their first echo within the first seven days of life, then subsequently developed severe pulmonary hypertension after an episode of sepsis; two died and one required pulmonary vasodilator for more than a year
Even in omphalocele patients without signs of respiratory compromise early, sepsis later puts these patients at high risk for pulmonary hypertension
Dr. Miguel Guelfand uses hydrocolloid dressing to make a silo for giant omphalocele without painting the sac, achieving closure in 97% within 30 days and 92% within 15 days in 40 patients
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