Malrotation
In the first two months of life, about 70% of volvulus cases occur, and by the first two years of life, 90% of volvulus cases that are going to occur do occur
In 20% of cases with true malrotations of the fore and mid-gut, you have a normal barium enema
A normal ultrasound does not rule out volvulus, supported by multiple studies
Ladd's bands do not cause midgut volvulus
Ladd's bands are thought to be an attempt of the body to fuse the cecum to the lateral peritoneal wall
The key reason to operate on an asymptomatic patient is to avoid midgut volvulus
The critical measurement is the distance between the ligament of Treitz and the ileocecal junction to prevent volvulus, though nobody knows the exact distance required
In patients with heterotaxy syndromes who have asymptomatic malrotations and undergo operations, the complication rate is remarkably high, between 30 and 50%
In a study from Edmonton on heterotaxy patients who underwent procedures for malrotation, the complication rate was about 50%
Host summaryThe host summarizing the discussion — not the host's own clinical position24:59
In a study by Papillon from Children's LA of about 200 heterotaxy patients, a quarter got screening upper GIs and three quarters did nothing; in 4 years there was only one case of volvulus, and in patients without bilious emesis and symptoms, no cases of volvulus
Host summaryThe host summarizing the discussion — not the host's own clinical position25:12
In the heterotaxy subgroup, the risk of volvulus in the early period (4-5 years) is actually very low if patients are not symptomatic
When bowel loops are dilated, this will always give you a low-lying ligament of Treitz
Atypical malrotation with a low-lying ligament of Treitz has some data showing lower risk of volvulus, though the data is not strong
In patients with rotation abnormalities, reversed mesenteric vessels may or may not be seen; it doesn't definitively indicate malrotation
In Jack's series of several hundred patients, there was never a case where the vessels were normal in a patient who had risk for volvulus (narrow base mesentery), so they use it as a screening test in sick patients
Upper GI is clearly better than ultrasound for diagnosing malrotation, but in a sick patient who can't get to radiology, ultrasound can be useful
Laparoscopic Ladd's procedure can be very effective even in a newborn, though if there's too much twist and no room, conversion to open may be necessary
In cardiac patients between first stage and Glenn procedure who get G-tubes, Nissen fundoplication is often requested because they vomit and are too small for PEGs
A 45-minute Nissen at pressures of 8 is tolerated by cardiac patients between stages
In a published study combining experience with Kansas City, the cardiac risk group did not stratify out to be at higher risk for reflux complications; neurologically impaired CP kids maybe, but not cardiac kids
Host summaryTodd Ponsky summarizing the discussion — not the host's own clinical position15:15
Yama does not operate on asymptomatic malrotation as long as the patient has non-bilious vomiting, is gaining weight, and is clinically well
Host summaryTodd Ponsky summarizing the discussion — not the host's own clinical position35:20
If a patient has a narrow pedicle, the patient always has vomiting and is symptomatic
Host summaryTodd Ponsky summarizing a resource — not the host's own clinical position36:16
Ladd's bands themselves are not risky; the risk is bilious vomiting and narrowing of the pedicle
Host summaryTodd Ponsky summarizing a resource — not the host's own clinical position36:39
In situs inversus or ambiguous cases, measuring the distance between ligament of Treitz and ileocecal junction matters regardless of where the bowels are; if less than half the diameter of the abdominal cavity, intervention is needed
Malrotation - Volvulus - Meconium Ileus - Solid Organ Injury: Update Course 2015
In heterotaxy syndrome with right atrial isomerism, there is a higher incidence of malrotation compared to left atrial isomerism.
In a Texas Children's series of 95 consecutive heterotaxy patients with malrotation, three-quarters underwent Ladd's procedure with no post-operative volvulus but 11% developed small bowel obstruction requiring admission and often surgery.
Host summaryKenneth Azarow summarizing a resource — not the host's own clinical position5:57
In the same Texas Children's series, 25% of heterotaxy patients were observed without surgery and had no small bowel obstruction or volvulus during 10-15 year follow-up.
Host summaryKenneth Azarow summarizing a resource — not the host's own clinical position6:20
Appendectomy carries a slight long-term complication rate from adhesions.
A low-lying ligament of Treitz defines malrotation, not simply the duodenum crossing midline, because a floppy duodenum can cross midline without malrotation.
Current literature shows overall success rates for meconium ileus enema reduction are declining on first attempts.
Host summaryKenneth Azarow summarizing a resource — not the host's own clinical position14:41