Long-Term Follow-Up of Surgical Outcomes for Patients With Wilms Tumor and Neuroblastoma

This single institution cohort followed survivors for a mean of 27 years after open oncologic resection for Wilms tumor and neuroblastoma

14% of patients required a repeat laparotomy

The most common indications for repeat laparotomy were small bowel obstruction or tumor recurrence

In Wilms tumor, obstruction typically occurred within the first year

In neuroblastoma, obstruction often developed more than a decade later, well beyond routine follow-up

Radiation dose was not associated with re-operation risk

Secondary malignancy was uncommon in this cohort

Hypertension after nephrectomy was not increased compared to population norms

Scoliosis occurred in roughly 10 to 13% of patients, higher than the general population

Scoliosis has multi-factorial contributors including surgery and possibly radiation

Even decades after treatment, these patients remain at risk for late complications that warrant long-term counseling and follow-up