Quality of Life Outcomes for Patients Who Underwent Conventional Resection and Liver Transplantation for Locally Advanced Hepatoblastoma

Survival for hepatoblastoma continues to improve.

Long-term quality of life is becoming a more important outcome as hepatoblastoma survival improves.

This is a single institution cross-sectional study using validated pediatric quality of life surveys to evaluate long-term survivors of hepatoblastoma.

Overall quality of life outcomes were similar between liver transplant and resection groups for hepatoblastoma.

There was no significant difference in emotional, social, physical, or school functioning outcomes between transplant and resection groups.

Patients who underwent resection had lower overall procedure anxiety scores than transplant patients.

The finding of lower procedural anxiety in resection patients was mirrored in the parents' surveys.

Long-term quality of life outcomes appear comparable between patients who undergo resection and liver transplantation for hepatoblastoma.

Surgical strategy for hepatoblastoma can be focused on oncologic control given comparable quality of life outcomes.